ID   J7QUI7_ENTFC            Unreviewed;       621 AA.
AC   J7QUI7;
DT   31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   31-OCT-2012, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=Relaxase {ECO:0000313|EMBL:CCJ27804.1};
OS   Enterococcus faecium (Streptococcus faecium).
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC   Enterococcus.
OX   NCBI_TaxID=1352 {ECO:0000313|EMBL:CCJ27804.1};
RN   [1] {ECO:0000313|EMBL:CCJ27804.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=MM5-F9a {ECO:0000313|EMBL:CCJ27804.1};
RX   PubMed=24078615; DOI=10.1128/JB.02165-12;
RA   Bjorkeng E.K., Hjerde E., Pedersen T., Sundsfjord A., Hegstad K.;
RT   "ICESluvan, a 94-Kilobase Mosaic Integrative Conjugative Element Conferring
RT   Interspecies Transfer of VanB-Type Glycopeptide Resistance, a Novel
RT   Bacitracin Resistance Locus, and a Toxin-Antitoxin Stabilization System.";
RL   J. Bacteriol. 195:5381-5390(2013).
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DR   EMBL; HE963029; CCJ27804.1; -; Genomic_DNA.
DR   AlphaFoldDB; J7QUI7; -.
DR   InterPro; IPR005094; Endonuclease_MobA/VirD2.
DR   InterPro; IPR021112; LtrB_C.
DR   InterPro; IPR048299; LtrB_central.
DR   NCBIfam; NF040665; relax_SAG1250; 1.
DR   Pfam; PF03432; Relaxase; 1.
DR   Pfam; PF11083; Relaxase_C; 1.
DR   Pfam; PF20874; Relaxase_M; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils}.
FT   DOMAIN          12..258
FT                   /note="MobA/VirD2-like nuclease"
FT                   /evidence="ECO:0000259|Pfam:PF03432"
FT   DOMAIN          384..469
FT                   /note="Group II intron-interrupted relaxase LtrB central"
FT                   /evidence="ECO:0000259|Pfam:PF20874"
FT   DOMAIN          483..605
FT                   /note="Group II intron-interrupted relaxase LtrB C-
FT                   terminal"
FT                   /evidence="ECO:0000259|Pfam:PF11083"
FT   COILED          263..300
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          482..543
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   621 AA;  74216 MW;  E96CF6CB5B9707FA CRC64;
     MVVTKHFATH GKKYRRRLIK YILNPDKTDN LKLVSDFGMS NYLDFPSYEE MVEMYNVNFT
     NNDKLYESRN DRQEKHQQNI HAHHLVQSFS PEDNLTPEEI NRIGYETMME LTGGRFRFIV
     ATHTDKNHVH NHILINAIDR NSDKKLIWNY ALERNLRMIS DRISKVAGAK IIEKRFSYRD
     YQKYRKISHK FELKQRLYFL MQQSKSFDDF LEKAVQLHVH IDFSQKHSRF MMTDRAMTKP
     IRGRQLSKRD LYDEEFFRTH FAKQEIESRL EFLLNLVNSL EELLTKAKEL NLTIDLKQKN
     VIFILEDNGN QFSLSHKKIS DKKLYDVNFF QDYFKNKEVG DSEGLENLKE QYHAFQEERD
     KDKVSTEKIE ETFETFREKR DAVHEFEVEL AEHQIEKLVD EGVYIKVSFG IKQSGLIFIP
     NYQLDILEEE NQTKYKVYIR ETTSYFVYNK EHSDKNQYIK GRTLIRQLTN DNRMIPYRRP
     TVERLQEKIS EINLLIELTE TDKQYQDIKD ELVSEIAELD IKLNQTNEKI ATLNKMAEVL
     INLKNEDASN RKLARYDFSK LNLTESITAE QVTEEIRVLQ EDLGHYLDEY EGLARKLDTF
     VKLLNTDKEQ SHNLRDDFQV E
//