ID J7S439_KAZNA Unreviewed; 1453 AA.
AC J7S439;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=RNA helicase {ECO:0008006|Google:ProtNLM};
GN Name=KNAG0B06360 {ECO:0000313|EMBL:CCK69064.1};
GN OrderedLocusNames=KNAG_0B06360 {ECO:0000313|EMBL:CCK69064.1};
OS Kazachstania naganishii (strain ATCC MYA-139 / BCRC 22969 / CBS 8797 / KCTC
OS 17520 / NBRC 10181 / NCYC 3082 / Yp74L-3) (Yeast) (Saccharomyces
OS naganishii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Kazachstania.
OX NCBI_TaxID=1071383 {ECO:0000313|EMBL:CCK69064.1, ECO:0000313|Proteomes:UP000006310};
RN [1] {ECO:0000313|EMBL:CCK69064.1, ECO:0000313|Proteomes:UP000006310}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-139 / BCRC 22969 / CBS 8797 / CCRC 22969 / KCTC 17520
RC / NBRC 10181 / NCYC 3082 {ECO:0000313|Proteomes:UP000006310};
RX PubMed=22123960; DOI=10.1073/pnas.1112808108;
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Evolutionary erosion of yeast sex chromosomes by mating-type switching
RT accidents.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011).
RN [2] {ECO:0000313|Proteomes:UP000006310}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-139 / BCRC 22969 / CBS 8797 / CCRC 22969 / KCTC 17520
RC / NBRC 10181 / NCYC 3082 {ECO:0000313|Proteomes:UP000006310};
RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., Byrne K.P.,
RA Wolfe K.H.;
RT "Genome sequence of Kazachstania naganishii.";
RL Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; HE978315; CCK69064.1; -; Genomic_DNA.
DR STRING; 1071383.J7S439; -.
DR eggNOG; KOG0920; Eukaryota.
DR HOGENOM; CLU_001832_4_0_1; -.
DR OMA; WLKFKAT; -.
DR OrthoDB; 53793at2759; -.
DR Proteomes; UP000006310; Chromosome 2.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProt.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0008186; F:ATP-dependent activity, acting on RNA; IEA:UniProt.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0022613; P:ribonucleoprotein complex biogenesis; IEA:UniProt.
DR GO; GO:0006396; P:RNA processing; IEA:UniProt.
DR CDD; cd17917; DEXHc_RHA-like; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR006575; RWD_dom.
DR InterPro; IPR015940; UBA.
DR InterPro; IPR009060; UBA-like_sf.
DR InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF145; ATP-DEPENDENT RNA HELICASE DHX29; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR Pfam; PF05773; RWD; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46934; UBA-like; 1.
DR SUPFAM; SSF54495; UBC-like; 1.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50908; RWD; 1.
DR PROSITE; PS50030; UBA; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000006310}.
FT DOMAIN 373..414
FT /note="UBA"
FT /evidence="ECO:0000259|PROSITE:PS50030"
FT DOMAIN 440..541
FT /note="RWD"
FT /evidence="ECO:0000259|PROSITE:PS50908"
FT DOMAIN 624..789
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 865..1033
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..45
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 197..252
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 20..44
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 197..212
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 213..248
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1453 AA; 163932 MW; 895641AC7B203C5E CRC64;
MAKKGKKNGA SPSPEVAPGK KGKKGSKSEE PAILTKEEQR AQQQAHRAKV TSTASWTGKL
PHTLLHEFCV KKKWNKVEYD MRRHGDKGMV ATAVLSWTDP KTKEVLKVKM NDPTFDRTTG
TGLLLPQETA AEARHMAAVV ALSRVAFNKN LQMMLPPNHK KLWYDLEDYR KLISKSDPRS
CARLFDLEPF TSMVEEKKTR EKAEEEFKAK QNQAEKTQQI PILITNASSS KPSSSSRRAG
NDRNKPSDGQ ITKIVKPAKT RRSLVKFPRK VWERASFVDL EESTRQMIEA TLKPVINWES
EMYKETPEKH AERAELEVKL VGIGFRQIHV KEAMQFKDPL SFLLFNLPDD DLPPFFHKRK
EDSKNKVEIA SLPLSTRLVV ERLTELGVSE DEAHYSLQEA RMNENEAVAI LMSEFVTVPP
SSADHSTEIS EEESLEMWRQ ELESLQCIDE SKVEDIVTDL SYSVVLEGGL KLKARLYRTQ
GYPYKLPGII VSTFDKKYKL PNYIKKQILS KLVNYLVEGN LIGDMLVYNI IEWLEDNIQN
IIDNPGSLLS QNDLATSSHS DTIRGNHAKS VYNKKKNSRN VSLSPQQLDS LHTEYLNRQK
TKQYKEMQEV RALLPAWKKQ DEIVELIEQN DVVLITGETG SGKSTQVVQF ILDALQNLKR
STKIICTQPR RISAIGLAER VADERCVTCG DEVGYTIRGV NMTKATTRIR FMTTGVLVRI
LQGDQSLLND SIVVIDEVHE RSIDTDLVVT LLKNLLGKVK GLKIVLMSAT VNVDLFSKFF
PQLGRCHIEG RTFPIKDYFL DDILEALDFK IKKNEKPQLY RYEDTDDLDN GSQGGDDGYI
RPGPDSNFFK SGQINYDLLC QVALHVDQEL KSGSNDGSII IFLPGVAEID KSCRMLKEMD
TSHRFVVLPL HSALTPEDQK KVFRRYGSKR KIVVSTNIAE TSITIDDCVA TIDTGRAKTM
YYNPRENTTR LIESFISKAE AKQRRGRAGR VRKGVSYKLF SKRLFEEDMV DMPAPEIKRV
ALESLYISVK AMGVKDVTSF LASGLESPPL QSLRKAERML TTVGLLEEDD RSLTQLGRYI
SLMPVMDSKQ GKLLIYSIIF GVTDLGVLTA SILSSGSQMF IGGRDNRDAI KKVLLRYQAR
GDLLAMVEIL RQYLSIEDKA AKRQFMRDNM LSYNKVSEIL SARAQYYSIL RDVGFLPMSY
RPWNGSPTFN ANESNSSVVE IILTGSFYPN VARVQLPDPK FLATSSGAIE KDPEAKTIKY
WVRNEEYVDK LSELRQTQTA SGSVDMDDMP LPSTRAFIHP SSVLFSDRNV NVEEIRALEG
AAEEGAADKY ASRNPMLKLP FLVYNSSHCT SKLFLNGITP TSTLSLLLFG GPISYDIHGE
QHSPGIVVDD WLPVRTWCKN AVLIKRLRQQ LDVSIREVLQ RPRYDSRPSD ARSDSDTATA
TSVIDLVVKI VGA
//
