ID J7SI30_STRSL Unreviewed; 1633 AA.
AC J7SI30;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 24-JAN-2024, entry version 50.
DE SubName: Full=Alpha-C protein {ECO:0000313|EMBL:EJO16087.1};
GN ORFNames=RSSL_02204 {ECO:0000313|EMBL:EJO16087.1};
OS Streptococcus salivarius K12.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=1200793 {ECO:0000313|EMBL:EJO16087.1, ECO:0000313|Proteomes:UP000006983};
RN [1] {ECO:0000313|EMBL:EJO16087.1, ECO:0000313|Proteomes:UP000006983}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Streptococcus salivarius K12
RC {ECO:0000313|Proteomes:UP000006983};
RX PubMed=23045482; DOI=10.1128/JB.01268-12;
RA Barretto C., Alvarez-Martin P., Foata F., Renault P., Berger B.;
RT "Genome Sequence of the Lantibiotic Bacteriocin Producer Streptococcus
RT salivarius Strain K12.";
RL J. Bacteriol. 194:5959-5960(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJO16087.1}.
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DR EMBL; ALIF01000003; EJO16087.1; -; Genomic_DNA.
DR PATRIC; fig|1200793.3.peg.1376; -.
DR Proteomes; UP000006983; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.10.20.890; -; 3.
DR Gene3D; 2.60.40.10; Immunoglobulins; 7.
DR InterPro; IPR044024; aRib.
DR InterPro; IPR041498; Big_6.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR019931; LPXTG_anchor.
DR InterPro; IPR012706; Rib_alpha_Esp_rpt.
DR InterPro; IPR005877; YSIRK_signal_dom.
DR NCBIfam; NF033510; Ca_tandemer; 3.
DR NCBIfam; TIGR01167; LPXTG_anchor; 1.
DR NCBIfam; TIGR02331; rib_alpha; 3.
DR NCBIfam; TIGR01168; YSIRK_signal; 1.
DR Pfam; PF18938; aRib; 1.
DR Pfam; PF17936; Big_6; 5.
DR Pfam; PF00746; Gram_pos_anchor; 1.
DR Pfam; PF08428; Rib; 3.
DR Pfam; PF04650; YSIRK_signal; 1.
DR PROSITE; PS50847; GRAM_POS_ANCHORING; 1.
PE 4: Predicted;
KW Cell wall {ECO:0000256|ARBA:ARBA00022512};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Peptidoglycan-anchor {ECO:0000256|ARBA:ARBA00023088};
KW Secreted {ECO:0000256|ARBA:ARBA00022512};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1607..1627
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1600..1633
FT /note="Gram-positive cocci surface proteins LPxTG"
FT /evidence="ECO:0000259|PROSITE:PS50847"
FT REGION 67..211
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 546..573
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 779..824
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 857..895
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 933..978
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1085..1106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1180..1206
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1347..1381
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1433..1454
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 787..812
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 866..881
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1088..1106
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1348..1375
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1434..1454
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1633 AA; 166775 MW; 5D4AB9E4DCC6D6BA CRC64;
MITCLGGNMG KDIFSKKSRF SIRKLNIGVC SVLLGTLIMI GHTAQADETT SDGATVAATA
VSASQGEGVP AATSPSTASE SVSTTTVTPA VTETVAATSV EPTSSAPANS VATSTSQAVA
SEATGSTNVS TAKPATASEV PASEASRSVT ASTTSSTTAS SEITNTNNIT VSETPNAPRV
RSRRSIAQGE TRSASTETRA SDGAQNLDYS NKENVQDYVQ ISYEVDKANN VLHWTVLDNP
GRKANSASGY VYFTIPKDSV GAPTNWNVVQ TDKNGKVVNT RNYWKDNDGS YLMGQNGRMN
TYTGAEMTKR LTQLYKDTKN PAIKGNEAAV AAQTAERSQA LYTMTADNNA LRNVMWTITF
DTPIVDKSKP LDYVAGMQGT GVIGGRTNIM TGFTDNFIDN ESSKFQAVAV KEKYTAKVGG
SFDADPATYV TNKAGTPEFP NNYRGATTFA WKDGQAPTAT QAGTHTKTVM VTYPAHYNQA
PQEVTVTFEV EEEATPAPEI TSDLSGKAST PADVTVKAPA GSTVKLYNND GVVIGEAVAN
DQGVATITPT NSLPEGEVTA TATPAGGSES AKSAPITVTK SPVTGEEGGL SRGSDNTQLL
VRKSHITVYP GDPVNVDVIA AATAIEKFWV PKNPTAISGV LPVGAFLTTA GSNTYRQRNA
AFQGTVAETQ PAGDTVVTFA VKSKKNVTVT RDLKVTVLET AKKYDPTSGE AKVEVADVSN
VSEAEKTKII DAVKAANTSL PSSATYSVDE KGNLVITYAD KSIDKIAAAY LVTPVKDXRS
DAEKNDPTAK AQTVTPGSTP TAQDSIGNAG DLPSGTTFAF KKPVDTATEG EKDATVVVTY
PDGTTDEVPV KVTVKDPRSD AEKNDPTAKA QTVTPGXTPT XXDSIGNXXD LPSGTTFEFK
TPVDTTTPGE KDATVVVTYP DGSKDEVPVK VTVKDPSAPA TDADKNTPVA KDQTVKPGDK
PSAKDSIGNV DDLPKGTTVE FKTPVDTTTP GEKDATVVVT YPDGSKDEVP VKVTVKDPST
PAKPVVATDL TDKAGTKTPV EVSAEPGSKV ELFDKDGNKI GEATADENGK ATITPTVAIP
AGNVTAKATD PAGNTSDASD PMVATTDTTA PAKPVVATDL TDKAGTKTPV EVSAEPGSKV
ELFDKDGNKI GEATADENGK ATITPTVAIP AGNVTAKATD PAGNVSDASD PMVATTDTTA
PAKPVVNPVK VGDTAITGTA EAGSTVEVTL PDGSKVSAKA DQDGNFSVPV SGLKEGDTVS
VTATDDAGNK SDATTATVAK AADTIAPDAP VVNPVKAGTT AVTGTAEAGS TVEVTIPDGS
KVSAKADQDG NFSVPVSGLK EGDTVSVTAT DDAGNTSNPT SVTVGKGTDT TAPSAPVVNP
VKAGTTEVTG TAEAGSTVEV TLPDGSKVSA KADQDGNFSV PVSGLKEGDT VSVTATDDAG
NTSSPTSVTV GKGIDTTAPS APVVNTDLTG KAGTRTPINV IAEPGSKVEL FDKDGNKIGE
ATADEKGLAV VVPTVNIPEG SVTARATDLA GNVSEASAPM FATTSGTVDS FNNGKGSENT
PTVVKPSLSG KVESSTTLAN HMNLKARANI SSTEKDASTL PETGDEVSIG GVVLGGILAA
AGLGLVGKRK KED
//
