ID   J9BDV0_WUCBA            Unreviewed;       494 AA.
AC   J9BDV0;
DT   31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   31-OCT-2012, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   RecName: Full=VWFA domain-containing protein {ECO:0008006|Google:ProtNLM};
DE   Flags: Fragment;
GN   ORFNames=WUBG_03694 {ECO:0000313|EMBL:EJW85395.1};
OS   Wuchereria bancrofti.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Wuchereria.
OX   NCBI_TaxID=6293 {ECO:0000313|EMBL:EJW85395.1, ECO:0000313|Proteomes:UP000004810};
RN   [1] {ECO:0000313|Proteomes:UP000004810}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NA {ECO:0000313|Proteomes:UP000004810};
RA   Nutman T.B., Fink D.L., Russ C., Young S., Zeng Q., Koehrsen M.,
RA   Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA   Goldberg J., Griggs A., Gujja S., Heilman E.R., Heiman D., Hepburn T.,
RA   Howarth C., Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M.,
RA   Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S.,
RA   Walk T., White J., Yandava C., Haas B., Henn M.R., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Wuchereria bancrofti.";
RL   Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EJW85395.1}.
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DR   EMBL; ADBV01001166; EJW85395.1; -; Genomic_DNA.
DR   AlphaFoldDB; J9BDV0; -.
DR   Proteomes; UP000004810; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   InterPro; IPR001507; ZP_dom.
DR   PANTHER; PTHR22907:SF47; CUTICLIN-6; 1.
DR   PANTHER; PTHR22907; UNCHARACTERIZED; 1.
DR   Pfam; PF00092; VWA; 1.
DR   SMART; SM00327; VWA; 1.
DR   SMART; SM00241; ZP; 1.
DR   SUPFAM; SSF53300; vWA-like; 1.
DR   PROSITE; PS50234; VWFA; 1.
DR   PROSITE; PS51034; ZP_2; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        462..486
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          1..151
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
FT   DOMAIN          168..411
FT                   /note="ZP"
FT                   /evidence="ECO:0000259|PROSITE:PS51034"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:EJW85395.1"
SQ   SEQUENCE   494 AA;  55880 MW;  156EC2B0592C9D23 CRC64;
     LNFTVHILRR INITEEGSRM GIIQYAENPQ LEITLNQYSH SNQMEWAIQR IKYLSGATNT
     GAALKFALER GFQNARGGSI PKVAVVVTDG QSQDSVAESA QQLRDAHVMV YAVGVTNLVN
     VHQLHQIAGN PARVLTVESF DDLSKTLADS LTWDMCKTEF RPGTPDIICG PDRIGVRAST
     KNPFDGYVFI MDHFHKKECR AGPEEFPDAR SIGITIPFTE CNIHRYRSLS PRGIFVEMTV
     VFMFHALFMT KVDQMVKVQC FYMEADKSVS VPMEVSMITT QFRETMYEMP LCQYTLRRGS
     QNGPVVEYAQ LGENVYHRWE CHDQTDTFGM LVHSCYVDNG FGDRVDILDS RGCGVDAVLL
     MTPEYDETLR LATKPYHVFK YADRPITLCL KLDAGCIGLT PPNCPKLEHN HIHNHDHAHE
     QNEIRRARSA LEFNTLDVFT PQLHIVENLP QCSNPTIQFP SFYVVITVTS IILNILLSTL
     ISVPFLRSRK NGNV
//