ID J9ENK3_WUCBA Unreviewed; 572 AA.
AC J9ENK3;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=ATP-dependent Clp protease {ECO:0000313|EMBL:EJW84066.1, ECO:0000313|WBParaSite:maker-PairedContig_975-snap-gene-0.9-mRNA-1};
GN ORFNames=WUBG_05024 {ECO:0000313|EMBL:EJW84066.1};
OS Wuchereria bancrofti.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Wuchereria.
OX NCBI_TaxID=6293 {ECO:0000313|EMBL:EJW84066.1, ECO:0000313|Proteomes:UP000004810};
RN [1] {ECO:0000313|Proteomes:UP000004810}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NA {ECO:0000313|Proteomes:UP000004810};
RA Nutman T.B., Fink D.L., Russ C., Young S., Zeng Q., Koehrsen M.,
RA Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E.R., Heiman D., Hepburn T.,
RA Howarth C., Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M.,
RA Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S.,
RA Walk T., White J., Yandava C., Haas B., Henn M.R., Nusbaum C., Birren B.;
RT "The Genome Sequence of Wuchereria bancrofti.";
RL Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EJW84066.1}
RP NUCLEOTIDE SEQUENCE.
RG The Broad Institute Genome Sequencing Platform;
RG Broad Institute Genome Sequencing Center for Infectious Disease;
RA Nutman T.B., Fink D.L., Russ C., Young S., Zeng Q., Koehrsen M.,
RA Alvarado L., Berlin A., Borenstein D., Chapman S.B., Chen Z., Engels R.,
RA Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S., Heilman E.R.,
RA Heiman D., Hepburn T., Howarth C., Jen D., Larson L., Lewis B., Mehta T.,
RA Park D., Pearson M., Richards J., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Walk T., White J., Yandava C., Haas B.,
RA Henn M.R., Nusbaum C., Birren B.;
RT "The Genome Sequence of Wuchereria bancrofti.";
RL Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|WBParaSite:maker-PairedContig_975-snap-gene-0.9-mRNA-1}
RP IDENTIFICATION.
RC STRAIN=pt0022
RC {ECO:0000313|WBParaSite:maker-PairedContig_975-snap-gene-0.9-mRNA-1};
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
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DR EMBL; ADBV01001837; EJW84066.1; -; Genomic_DNA.
DR STRING; 6293.J9ENK3; -.
DR WBParaSite; maker-PairedContig_975-snap-gene-0.9-mRNA-1; maker-PairedContig_975-snap-gene-0.9-mRNA-1; maker-PairedContig_975-snap-gene-0.9.
DR Proteomes; UP000004810; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd19497; RecA-like_ClpX; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR48102:SF7; ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR48102; ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:EJW84066.1};
KW Protease {ECO:0000313|EMBL:EJW84066.1}.
FT DOMAIN 254..416
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 470..562
FT /note="Clp ATPase C-terminal"
FT /evidence="ECO:0000259|SMART:SM01086"
FT REGION 189..208
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 572 AA; 62980 MW; 4CE745419E1DDB52 CRC64;
MVCPSSAVVI ARRQCQSFLI VRTVRYIAKG GGSSNDSGSS TDDWENNNTS SEHILFRQRI
ALHAPVPLTG KHVTTRWNIW RTSSSNSRCD ECGKPLKNIP SSTPSSRYLI CENCRRLFSC
GPPDEDDEKG SILRASEADK KPPYPKEIYG FLNKYIIGQE QAKKTLSVGV YQHYLRLYHN
IENNVSSPAM NNAEGNRPRT GASSSGVLYQ EDYSRTSRAD IRFFSEVTAP QQKYRIASPV
FRPLPENDVP IRLEKSNILL LGPSGVGKTF ITQTLARILD VPIALCDCTS MTQAGYVGED
VESVVQKLVQ NAGGNVERAQ QGIVFLDEID KIAAAHNVQS HAFRDVSGEG VQHALLKLVE
GTLVNVKSSR KSMSTQQDFV QVDTTDILFV ASGAFTALDR IVGKRLDRKT LGLGAKSGMQ
RITDDDKLEA AISKKRDDLL RQADQGDLIS FGIVPELVGR FPVIVPFHSL DKGMLVRVLT
EPTNSLLAQK KLEFAMDGAD LSFSSDALDE IAALALERRT GARALRSIVE KVLLEAKFTV
PGSDIESVHI NRECVQGKAD YVYTRRAQQA TG
//
