ID   J9F0H0_WUCBA            Unreviewed;       482 AA.
AC   J9F0H0;
DT   31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   31-OCT-2012, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   RecName: Full=Elongator complex protein 2 {ECO:0000256|ARBA:ARBA00020267};
DE   Flags: Fragment;
GN   ORFNames=WUBG_08221 {ECO:0000313|EMBL:EJW80869.1};
OS   Wuchereria bancrofti.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Wuchereria.
OX   NCBI_TaxID=6293 {ECO:0000313|EMBL:EJW80869.1, ECO:0000313|Proteomes:UP000004810};
RN   [1] {ECO:0000313|Proteomes:UP000004810}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NA {ECO:0000313|Proteomes:UP000004810};
RA   Nutman T.B., Fink D.L., Russ C., Young S., Zeng Q., Koehrsen M.,
RA   Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA   Goldberg J., Griggs A., Gujja S., Heilman E.R., Heiman D., Hepburn T.,
RA   Howarth C., Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M.,
RA   Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S.,
RA   Walk T., White J., Yandava C., Haas B., Henn M.R., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Wuchereria bancrofti.";
RL   Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA
CC       biosynthesis. {ECO:0000256|ARBA:ARBA00005043}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC       Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the WD repeat ELP2 family.
CC       {ECO:0000256|ARBA:ARBA00005881}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EJW80869.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; ADBV01004130; EJW80869.1; -; Genomic_DNA.
DR   AlphaFoldDB; J9F0H0; -.
DR   UniPathway; UPA00988; -.
DR   Proteomes; UP000004810; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0033588; C:elongator holoenzyme complex; IEA:InterPro.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0002098; P:tRNA wobble uridine modification; IEA:InterPro.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 3.
DR   InterPro; IPR037289; Elp2.
DR   InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_rpt.
DR   PANTHER; PTHR44111; ELONGATOR COMPLEX PROTEIN 2; 1.
DR   PANTHER; PTHR44111:SF1; ELONGATOR COMPLEX PROTEIN 2; 1.
DR   Pfam; PF00400; WD40; 5.
DR   SMART; SM00320; WD40; 6.
DR   SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR   PROSITE; PS50082; WD_REPEATS_2; 3.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE   3: Inferred from homology;
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT   REPEAT          13..45
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          110..141
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          375..406
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:EJW80869.1"
FT   NON_TER         482
FT                   /evidence="ECO:0000313|EMBL:EJW80869.1"
SQ   SEQUENCE   482 AA;  54396 MW;  E750FB282415CFDD CRC64;
     ITYTINVTLQ GVLNAHEDWI YSVEWHTSKL QLLSASNDKT IIIWEPSESA AGLWFDSVRV
     GDVGGQAVGF FGACFSPDGY AILAYSYFGG FCSWQIEKEG SSYWKSVSTF GGHSGQVRDI
     TWDPTGSYLL SCSHDQTTRC YAPSANHDVI IEVARPQVHG YDLTSIASIS SSRFVSGADE
     KILRVFAAPR NFVETLKVVS KYDCQKLFPD PTQIVGYNAA IPALGLSNKI TSVVNIQSNE
     NSSADDTLNE NVPFMKGVPI EECLMQDTLW PEIHKLYGHG FEVFTVASNH SGTLIASACK
     ASRVESATII IWDNKQWRRR CELQCHKLTV VQLAFSNNDL FLLSVSRDRT FAISVRSLQD
     PFQWKLQLTS EQKYSKVHSR IIWCCAWTPD DKYFVTGARD KKLCLWRFDG NDIQLIAERK
     HLHAVTAVDF APKLWNKHYI LAVGFENGEI EIEKWNLHQN DINTSDNCLK RWLAHSQTIN
     RL
//