ID J9FE53_WUCBA Unreviewed; 363 AA.
AC J9FE53;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=Zinc finger Ran-binding domain-containing protein 2 {ECO:0000256|ARBA:ARBA00017543};
GN ORFNames=WBA_LOCUS2568 {ECO:0000313|EMBL:VDM09182.1}, WUBG_03458
GN {ECO:0000313|EMBL:EJW85634.1};
OS Wuchereria bancrofti.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Wuchereria.
OX NCBI_TaxID=6293 {ECO:0000313|EMBL:EJW85634.1, ECO:0000313|Proteomes:UP000004810};
RN [1] {ECO:0000313|EMBL:EJW85634.1}
RP NUCLEOTIDE SEQUENCE.
RG The Broad Institute Genome Sequencing Platform;
RG Broad Institute Genome Sequencing Center for Infectious Disease;
RA Nutman T.B., Fink D.L., Russ C., Young S., Zeng Q., Koehrsen M.,
RA Alvarado L., Berlin A., Borenstein D., Chapman S.B., Chen Z., Engels R.,
RA Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S., Heilman E.R.,
RA Heiman D., Hepburn T., Howarth C., Jen D., Larson L., Lewis B., Mehta T.,
RA Park D., Pearson M., Richards J., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Walk T., White J., Yandava C., Haas B.,
RA Henn M.R., Nusbaum C., Birren B.;
RT "The Genome Sequence of Wuchereria bancrofti.";
RL Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000004810}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NA {ECO:0000313|Proteomes:UP000004810};
RA Nutman T.B., Fink D.L., Russ C., Young S., Zeng Q., Koehrsen M.,
RA Alvarado L., Berlin A., Chapman S.B., Chen Z., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heilman E.R., Heiman D., Hepburn T.,
RA Howarth C., Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M.,
RA Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S.,
RA Walk T., White J., Yandava C., Haas B., Henn M.R., Nusbaum C., Birren B.;
RT "The Genome Sequence of Wuchereria bancrofti.";
RL Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|WBParaSite:maker-PairedContig_2166-snap-gene-1.13-mRNA-1, ECO:0000313|WBParaSite:maker-PairedContig_4939-snap-gene-0.11-mRNA-1}
RP IDENTIFICATION.
RC STRAIN=pt0022
RC {ECO:0000313|WBParaSite:maker-PairedContig_2166-snap-gene-1.13-mRNA-1,
RC ECO:0000313|WBParaSite:maker-PairedContig_4939-snap-gene-0.11-mRNA-1};
RG WormBaseParasite;
RL Submitted (NOV-2016) to UniProtKB.
RN [4] {ECO:0000313|EMBL:VDM09182.1, ECO:0000313|Proteomes:UP000270924}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the ZRANB2 family.
CC {ECO:0000256|ARBA:ARBA00025731}.
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DR EMBL; ADBV01001061; EJW85634.1; -; Genomic_DNA.
DR EMBL; UYWW01000730; VDM09182.1; -; Genomic_DNA.
DR STRING; 6293.J9FE53; -.
DR WBParaSite; maker-PairedContig_2166-snap-gene-1.13-mRNA-1; maker-PairedContig_2166-snap-gene-1.13-mRNA-1; maker-PairedContig_2166-snap-gene-1.13.
DR WBParaSite; maker-PairedContig_4939-snap-gene-0.11-mRNA-1; maker-PairedContig_4939-snap-gene-0.11-mRNA-1; maker-PairedContig_4939-snap-gene-0.11.
DR OMA; DLWGDNE; -.
DR Proteomes; UP000004810; Unassembled WGS sequence.
DR Proteomes; UP000270924; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR Gene3D; 4.10.1060.10; Zinc finger, RanBP2-type; 2.
DR InterPro; IPR001876; Znf_RanBP2.
DR InterPro; IPR036443; Znf_RanBP2_sf.
DR InterPro; IPR017337; ZRANB2.
DR PANTHER; PTHR12999:SF17; ZINC FINGER RAN-BINDING DOMAIN-CONTAINING PROTEIN 2; 1.
DR PANTHER; PTHR12999; ZINC FINGER RAN-BINDING DOMAIN-CONTAINING PROTEIN 2 ZRANB2-RELATED; 1.
DR Pfam; PF00641; zf-RanBP; 1.
DR PIRSF; PIRSF037956; UCP037956_ZnF_Ran; 1.
DR SMART; SM00547; ZnF_RBZ; 2.
DR SUPFAM; SSF90209; Ran binding protein zinc finger-like; 2.
DR PROSITE; PS01358; ZF_RANBP2_1; 2.
DR PROSITE; PS50199; ZF_RANBP2_2; 2.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000270924};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00322};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00322}.
FT DOMAIN 32..63
FT /note="RanBP2-type"
FT /evidence="ECO:0000259|PROSITE:PS50199"
FT DOMAIN 85..114
FT /note="RanBP2-type"
FT /evidence="ECO:0000259|PROSITE:PS50199"
FT REGION 146..224
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 244..363
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 146..201
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 202..221
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 246..265
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 278..363
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 363 AA; 41615 MW; 0D8DC976E2B86622 CRC64;
MNSDDASRYL ERQRQMASNV VTAPSTHRRA LRDGEWACID AKCAYINADR VSVCERCGKA
KPRSKNRVGR EIGKDAAEKS KGLFAAEDWA CTKCGNVNWA RRTACNICNA PKLGDLEVRT
GYGGGYMDRQ NVEYIEREDD EEFDEFGRKK KRRKLDSKAE EEQKVGGPEE CVKYSEKESE
EGKEKIEEIE SDTKQAVSGD NDEEVEAEED DEDENDADLD KYDLSADEFE VENLKAKIAA
RKAALASSVT KTQVRSESRC SSDCSCSCSG GECSCEESEN EEERKRSSRD VEREKEKGDT
RIKDRDSARD KEKEKERDRE RRDERSSKDE RDRNRHSQRN SQCRDNSPRR HHSSSAHRDK
DRR
//
