ID J9G5S6_9SPIT Unreviewed; 5200 AA.
AC J9G5S6;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=DENN domain containing protein {ECO:0000313|EMBL:EJY85661.1};
GN ORFNames=OXYTRI_16354 {ECO:0000313|EMBL:EJY85661.1};
OS Oxytricha trifallax.
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata; Spirotrichea;
OC Stichotrichia; Sporadotrichida; Oxytrichidae; Oxytrichinae; Oxytricha.
OX NCBI_TaxID=1172189 {ECO:0000313|EMBL:EJY85661.1};
RN [1] {ECO:0000313|EMBL:EJY85661.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JRB310 {ECO:0000313|EMBL:EJY85661.1};
RX PubMed=23382650; DOI=10.1371/journal.pbio.1001473;
RA Swart E.C., Bracht J.R., Magrini V., Minx P., Chen X., Zhou Y.,
RA Khurana J.S., Goldman A.D., Nowacki M., Schotanus K., Jung S., Fulton R.S.,
RA Ly A., McGrath S., Haub K., Wiggins J.L., Storton D., Matese J.C.,
RA Parsons L., Chang W.J., Bowen M.S., Stover N.A., Jones T.A., Eddy S.R.,
RA Herrick G.A., Doak T.G., Wilson R.K., Mardis E.R., Landweber L.F.;
RT "The Oxytricha trifallax Macronuclear Genome: A Complex Eukaryotic Genome
RT with 16,000 Tiny Chromosomes.";
RL PLoS Biol. 11:E1001473-E1001473(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJY85661.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AMCR01002886; EJY85661.1; -; Genomic_DNA.
DR EnsemblProtists; EJY85661; EJY85661; OXYTRI_16354.
DR OrthoDB; 2914316at2759; -.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR Gene3D; 3.40.50.11500; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR040848; AAA_lid_7.
DR InterPro; IPR011704; ATPase_dyneun-rel_AAA.
DR InterPro; IPR001194; cDENN_dom.
DR InterPro; IPR043153; DENN_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR031248; RNF213.
DR InterPro; IPR037516; Tripartite_DENN.
DR PANTHER; PTHR22605:SF1; RZ-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR22605; UNCHARACTERIZED; 1.
DR Pfam; PF07728; AAA_5; 1.
DR Pfam; PF17867; AAA_lid_7; 1.
DR Pfam; PF02141; DENN; 1.
DR SMART; SM00382; AAA; 2.
DR SMART; SM00799; DENN; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50211; DENN; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}.
FT DOMAIN 4746..5200
FT /note="UDENN"
FT /evidence="ECO:0000259|PROSITE:PS50211"
FT COILED 1230..1257
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 5200 AA; 616468 MW; E3610BB4020A7AE7 CRC64;
MVDHYISNQL SEYARIEDKF DAQNISDDDL DDKCIHFYLI TTKQEQKTAF RLKFRNLPSL
KDPVIKMDRL QDGNIFHVLV QLPTQDLRTI TDLKYSFIKT GTSGEDQVET GESEQERTKA
KKFLKLNSFF DIYQNKKQII NSLIINQKKE YYDALIRFFF NNYEDKEKHY GVPQIFNEFQ
DFINCEGGSY PISPTLKILT EYYLNVADDV EINLYMFELL SYFDGKILLK KSDSLKSLLQ
RMIELPFGFL RKIILDTKDL INHERILKGF KNLIQLEALI GLEFFDNINV ISDQKKFLNK
QLSLKDEFRF NKFKDIIRNA RTSNTYNDQS VQLLIYHALM ESKSLDNFLT NVEYLEKFAT
SNVIQDACKD IKQRQNKNYN YSAFIKQYLE RLLVIPQFKM VFAQEIRDCI DINLKNNFNS
PYFPQLLLDN PDLLTHSFLD KLVHHSKNFY LQANYMELMV KHIPMRKQQR PFKDIKSLIT
QNFYFQLFSC KNIPEQYQVL SKQIDYINNP VFEMIDKFDK EYLYKTMKQH MFTVFRQQYA
IQWMLDTLIR VRNNPDEQIF KVKLLSEVIH DVIKEHTMDN TNIKTIIKML FPRPQYRLTF
KEFKDIADIA LNGLGKLIEK ERRNLYEDDL VLCAIKIGQN YQENEVIVKI RSIVIEFIKK
LRDETITLRE VNQTIVANKK NLKEIILLFD PDFDLNQLEE LKKINQIFKH QIEIHQIYLL
WASKSFLNVS IKNYQSKLDK IILAQEQQLQ ARNAKNQDHF VQFQAFKTID KIYHFRDSKV
FENLFHSLPD EIAKNNVHFE ENKDLETGVY QIRMEGYDKA VQEYLFGKIV KDHFKNLTEY
PQTQIQQQEI WKFWKNIQPD DVQNEIQIIK DFLKLPDLNN FNGSIKTELN DQLEADIKNF
TMQELFRVRS EIINYLQIYT GKESNQNLDS SQSLKRMIQF QDQMKNSNPQ ESLESVSKRV
SKITEDFTNI DSYYNINWSH LEEYVRSKDT YEFCIQVSGF EFNSLYEYMD DSAAMNNRTI
ESISAASTFF DQLYKKIESS NFNEFERLME LLSSELQQQI EKDSDFSGKL VNCLENLQEI
KHMTSSSRNA SENTLQIIES ALENGIFVFQ LKHGKFQFFL EIMIKQRSKT EDNKSAIKDE
QQNSVNVSSL ILQKEKIYQH SSRAKLFIHS KTTSLQRQQQ VKVIDKIFTQ SVDLCKEIYQ
FILNLNQYGH LDYQDDQEFF RVPIQRENIV ADLQIKYKHL KDQYESLKKS LDIQRKRFYF
LNYVPNQLVA QLNYPFQDHQ QLEKVVQQLI KSKVFKNYFR IQSDIKDNIQ ILQELQDFWE
KENQINTEQE IEQSLRKDYG YQLQSGRVQH KLVSDNISLI KAVCSIFAIS KMYPTFDRVL
FCEEQTQLVE LQTFVNRSIM YPSGPKASKP YVIANFQKLP FAVQYLCYEY IMSNQGVYDL
QNTYFTLYIL SIQTPNQTTR LIELLRNSPP YQQYIKDDYM RDYFKYYENI KVVRSPQCGL
GKTQFIKQQA IKYHAQILRI PIYGEIQKQK IIKIFEDNLS KIQDGKKFII HYDVYPCGKE
DLNVILFELL ILKCLNYQFQ EIFSIPSSSG LKVFIEISYG LNEKLTSLFI HDNLKYVEQR
WDFASINVKL ESNDKFQKVC RYLLALQQKP KKYDPKELLQ PKQPLNEIDC QVILRNSFSR
MLRNQNYYFV NSFVDFVGDQ IRRMEESIFF TQENLERQMT GFLGFQVAKK ARKFHREIIS
QLINLSQRIS IVEKFSDIHE PSQNLERRAL EEEQANRFRD LEWDIFNHPF IVFNDGGNIT
PIYKDVKSVP EAVIDYHKNA NRHNKQNQQL KLYDDLSQDE FIEKILEICV SDSRREKIRK
MKDLKNLVFT LDNFMKLVLI YLRIRNFQPI VLMGETGVGK TSLVEYLAKI IDAEFQVLNI
HAGISENYII NFVKNANDIA KCQAGDSIEQ RRKIILFFDE INTNENINGL LKEIFIDRHI
NGQPIQRNIC LVAACNPFKL RRQEISGLTS GLKMNDRDTT MSRLVYRVIP LPESLVPFIW
DYKSLNRNEE IQYIRKMIEK TFDESLIFGQ GLNLVYMWAG DKNQNQKQKS KAQLYVAEIK
RIADTVFQAQ SIIKEQEDSP WAVSLRDVSR FCKLFVYFYQ NNSNQDKRSK PRGPNDQIFG
NRDIALVLSL YFCYVIRISE QDKRNSFISK LHKTLGVQAN NCINPQNFKT IVNQEQNRFI
REMEIKKGIG MSQTLKENIF VIITCILNNI PLIITGKPGS SKTLAMNLIT KSFKGLLSSK
AFFQQFPSIV PFYYQGSEQT TSKSIEKIYK KAIKAKEKLK DKNSRVVVVF DEIGLAEQSI
HNPLKVLHSL LEPPQVAFVG ISNWSLDASK MNRVITLSRY DPDQYDLLET ALSIARNYNP
NYSQKQLIPL VDWYLEYMDK QRRSQQNENF HGLRDFYSLI KYISPRMNSS EENNEKVILK
GVQRNFGGLN SNDAISLLDD KLNFKYIEDL YSCKPDQLII ENLLDQESRH LMIITDNFEN
SLQFIQDQCQ KQTREIEILY GSDFPDDQNE DATYEQINEI IFNMESGTLC VFLNLKNVYQ
SFYDMLNQNY TEIGTQNTQK YSKVAVGADQ SLFLVHQNFK CILVVDQNQI KDLDGPLKNR
FEKQLYTEEI STTLSHRQIK DEISQWTYQI SKVHRFEKKQ MFPTIDEKQS YQQLIIQSKD
LYGDNDEIIK QECKKSLIRV ATFQGIIRSQ LSQVVDKNIW YKEYFNQPHH FDLYQLIDHY
YNNWKDEKCF QNLSGFNLIT YTFSSLLDQK VLKDKYKDKI EDSIELSNIH KKKQFKQLIE
SYFNKENKNE LLLIFADMMV MNITKNIINL CRSKINSERT KRSLLPDSDQ LVNKHICFII
KLDFTKESND HYVSFGKDWR QYMVDLLNGR GHQEITIKQL FDNNIESLIK ISSSKKTMFE
QALVEGLSKI FYKKPQKFIT ERLEKIQNIF NQVSNNEFLT ELIVCKFQKN PMYDSIMNSW
RSDVVCNDFL MKSNLTFHGA ALEFIKTELV NHLAFVISYL EQDGIITSYE NEDLFEMAKG
YFTNLFRNNI INNRFLNVYY LNFNFDRIRF PLARVIHQQF SQLRVQFMKN DKQFDDSKIN
LYQKSQNDND FIDLNSIELS LDDLPHERQM SSKQKENQRL IYIKKKEILQ KDKHLSRNID
NLNSWCVLYF PKEYINKKML TENNMQYLED FSYLINNQES KQFTDSSVDY YKRYLSNSIK
YFLKEKIITD KTMSKSKIYG IYWKYENLFL NVWKIIYENQ KYKPYIEIEE KLIKEILKNP
HYLDTDFKYL PKEAFVESVI KVFFEIYYPS EQVFDFVVWE NNVKSTFQRL NDLSFYYQGV
TQTQESRVII FLLRYYQEII KYGGVKANTN NFIEFAKNIK EIFQMPQLLV QYLLELMEET
WLQKKDLELK KRIFKIACEY IIESYQLLEN IDFNFLINKV LVLLISNKSE LYSLQHKDSY
KFTLQSLITI VTSIIRSQNY GVTDKSCFSE IIEGDQVNYD TNVEKYHLVK ILNDFVIAYS
HSISRSDPLI ISLTDQLIDF IKYDPFDHLP RMKNALDHIR HIFTNSNMDH VSLQQLIAVA
AFKKIAKIQV QEIEYLSKDD DTMAVDLAVI IDQFFQCDNE QQRISMQPFA IYLMKLLYQK
YDFERKDRDF LRPLVGWFDQ FQKIDFERDI ISFSYIRQSE FNQVYEKFQS QLPVIDESVH
KKSPLNKFLQ ILALIDSFYI QKRKQEVPKN QIDIFAKNQC LTQDPNLQDF LRPFVDQVFD
KVPRNMFLRI DDLKGEKYHY KLLSMMIGSA GFANQNLFFY QFFVSPQKMK DSFVPFVQNF
IGDSEYQKMF KNNDKLSCLE CIHCKRQTLR IELSDYNSAS QKTLTHGERR CRHKDPNQSD
KVCNNKLINK QEPISSLKNV RSGVESFIIK NTNELAKKSY IPFERESYNQ VQIRKLNRYQ
LATGRILLHC MLMFCLSFCK QDNAMLEIIL TDYLYSGKKY EEYLADALKY LSYCINQDWE
FLKTVYFLND EKVSQIIQFI IVEIVKTQNG AYDYEKLRTI DGRKHMEQNF KVISDQIFGD
LKMFFTTKVQ QSSPLEMYLL ENNKLQQNDY YHLLRSINQT SIVHFERFVI EDWRDDTNFF
RMLFEQKESI KNLRQLKYLV EWARYIFDKY STQLTYDEAN EMTIQEAMER DFQQNQASRE
YRKKKQKDFK KFKQAWNTFT GLIIKDKDVE VVIPEISEQS KLMLCCLTKD KKDQLGQVFY
ILIKYLTQKQ DKVLKEAEKL FKEHSVNSIR FPKIQLLNLK QESVIYFREK QKIIDKRERA
LTAKVSELQE NQLEEMQFDE ELIDTRQQNL QIQEAKKLEE ELFEELIIKN SACSLQYSKG
MFVEYDIDKI KTQTIEILLK GKHMIELDDQ NSGLNFQFVN LGNLYSQIQE VCELIPQERS
SLSKALISQI RSDLDIYDIV QDFKTAFNYL TQCAVDSDQN LNLFLLEYKL EKFTRAINNE
FILQELKLKH ILDVYQKFEG RIFHIVLDLI HEKYQEKVTK IQQDWLVYIL DQEVLMIPKL
LKAIGRLCAR LLSSNYVLVD PNTNLFEFIT SQEMNLLFNA SDDIDFDLYQ IILSQSDVLV
SQSLEIYKIL SKLLKRNTKR IAQLKSQQNE ENKEDQYISN DEQIQVIKVQ DPFQDSFINE
QSEESKSSQI NRQTIRESQI MQAISRYSSS LFESIAPSSL ETKNINHKEM LFNEFFIVSG
DLTQIKHDQL VSNNQNQTYI DSKILFLHSE KNPNTSDARK IQAKCFCFPN GVLAKQVKDQ
QISSNLRQFN TNYSKKNSFI FTIPTSEEDG FDTKVQSHYY FICIIKDELV DVQVGKKRYY
YTVQKAYCLM TLYKYFDFHL QVLNSILSLY KAEKVKLENQ LRKQIFSDLD LEKEVAIKMP
LITKDIEKLL DNYFQLKPIQ NNLRVSFPES SKEINFNVPI QKTSIELNDL FWYAPFFMMT
IKIDEFYRLL SAVLMEVSVI FISDSLPMLS SAAIGIQCFL EPFQWCHTSI PILPKDLLEI
TAAPTPFIVG ILRDQESEIE WDEITNQCLL VDIKIDAQTV EITESGGKYP KPHFNGLKNI
LRQQFVKLNN EEIDYQLDNQ TMKQTLQRIY EFVKYSIQIF VINKLPLDLL QGKRKLADLD
EVKGLIKSQT SEADLPFVEI LLETQMFQYY VDGKYCQISQ
//
