ID   J9GJK4_9ZZZZ            Unreviewed;       555 AA.
AC   J9GJK4;
DT   31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   31-OCT-2012, sequence version 1.
DT   13-SEP-2023, entry version 38.
DE   SubName: Full=Aspartate--tRNA ligase {ECO:0000313|EMBL:EJW99779.1};
GN   ORFNames=EVA_12109 {ECO:0000313|EMBL:EJW99779.1};
OS   gut metagenome.
OC   unclassified sequences; metagenomes; organismal metagenomes.
OX   NCBI_TaxID=749906 {ECO:0000313|EMBL:EJW99779.1};
RN   [1] {ECO:0000313|EMBL:EJW99779.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=23251564; DOI=10.1371/journal.pone.0051521;
RA   Alcaide M., Messina E., Richter M., Bargiela R., Peplies J., Huws S.A.,
RA   Newbold C.J., Golyshin P.N., Simon M.A., Lopez G., Yakimov M.M., Ferrer M.;
RT   "Gene sets for utilization of primary and secondary nutrition supplies in
RT   the distal gut of endangered iberian lynx.";
RL   PLoS ONE 7:E51521-E51521(2012).
CC   -!- SIMILARITY: Belongs to the class-II aminoacyl-tRNA synthetase family.
CC       Type 1 subfamily. {ECO:0000256|ARBA:ARBA00006303}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EJW99779.1}.
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DR   EMBL; AMCI01003655; EJW99779.1; -; Genomic_DNA.
DR   AlphaFoldDB; J9GJK4; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0004812; F:aminoacyl-tRNA ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0006418; P:tRNA aminoacylation for protein translation; IEA:InterPro.
DR   CDD; cd00777; AspRS_core; 1.
DR   CDD; cd04317; EcAspRS_like_N; 1.
DR   Gene3D; 3.30.1360.30; GAD-like domain; 1.
DR   Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR   HAMAP; MF_00044; Asp_tRNA_synth_type1; 1.
DR   InterPro; IPR004364; Aa-tRNA-synt_II.
DR   InterPro; IPR006195; aa-tRNA-synth_II.
DR   InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR   InterPro; IPR004524; Asp-tRNA-ligase_1.
DR   InterPro; IPR047089; Asp-tRNA-ligase_1_N.
DR   InterPro; IPR002312; Asp/Asn-tRNA-synth_IIb.
DR   InterPro; IPR047090; AspRS_core.
DR   InterPro; IPR004115; GAD-like_sf.
DR   InterPro; IPR029351; GAD_dom.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR004365; NA-bd_OB_tRNA.
DR   NCBIfam; TIGR00459; aspS_bact; 1.
DR   PANTHER; PTHR22594:SF5; ASPARTATE--TRNA LIGASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR22594; ASPARTYL/LYSYL-TRNA SYNTHETASE; 1.
DR   Pfam; PF02938; GAD; 1.
DR   Pfam; PF00152; tRNA-synt_2; 1.
DR   Pfam; PF01336; tRNA_anti-codon; 1.
DR   PRINTS; PR01042; TRNASYNTHASP.
DR   SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR   SUPFAM; SSF55261; GAD domain-like; 1.
DR   SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR   PROSITE; PS50862; AA_TRNA_LIGASE_II; 1.
PE   3: Inferred from homology;
KW   Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146};
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:EJW99779.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917}.
FT   DOMAIN          110..536
FT                   /note="Aminoacyl-transfer RNA synthetases class-II family
FT                   profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50862"
SQ   SEQUENCE   555 AA;  62882 MW;  3BF60D0360FBF9FA CRC64;
     MGGMTFVDLR DRYGITQLVF NEEVDAILCE QANHLGREFV IQATGVVNER FSKNVNIPTG
     DVEIIVSELV VLNTAMTPPF TIEDNTDGGD DIRMKYRYLD LRRNAVRKNL ELRHKMTIEV
     RKYLDSKGFI EVETPILIGS TPEGARDFVV PSRMNPGQFY ALPQSPQTLK QLLMVSGFDR
     YFQIAKCFRD EDLRADRQPE FTQIDCEMSF VQQDDVIELF EGMAKYLFKE LRGVELTESF
     MRMSWADAMK YYGSDKPDLR FGMKFVELMD ILKGYGFSVF DNAAYIGGIC AEGAAHYTRK
     QLDALTEFVK RPQIGAKGMI YARIEANGNV KSSVDKFYSQ EVLQQMKEAF GAKPGDLILI
     LSGDDAMKTR RQLCALRLEM GNQLGLRDKN KFALLWVVDF PMFEWSEEEG RLMAMHHPFT
     HPKDEDIPLL DTDPAAVRAD AYDMVCNGIE VGGGSIRIHD AKLQAKMFEI LGFTPEKAEE
     QFGFLMNAFK YGAPPHGGLA YGLDRWVSIF AGLDSIRDCI AFPKNNSGRD VMLDAPSVID
     QKQLDELNLV VNVKE
//