ID J9IFM7_9SPIT Unreviewed; 800 AA.
AC J9IFM7;
DT 31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2012, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE RecName: Full=Protein SDA1 {ECO:0000256|RuleBase:RU365057};
GN ORFNames=OXYTRI_23079 {ECO:0000313|EMBL:EJY79642.1};
OS Oxytricha trifallax.
OC Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata; Spirotrichea;
OC Stichotrichia; Sporadotrichida; Oxytrichidae; Oxytrichinae; Oxytricha.
OX NCBI_TaxID=1172189 {ECO:0000313|EMBL:EJY79642.1};
RN [1] {ECO:0000313|EMBL:EJY79642.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JRB310 {ECO:0000313|EMBL:EJY79642.1};
RX PubMed=23382650; DOI=10.1371/journal.pbio.1001473;
RA Swart E.C., Bracht J.R., Magrini V., Minx P., Chen X., Zhou Y.,
RA Khurana J.S., Goldman A.D., Nowacki M., Schotanus K., Jung S., Fulton R.S.,
RA Ly A., McGrath S., Haub K., Wiggins J.L., Storton D., Matese J.C.,
RA Parsons L., Chang W.J., Bowen M.S., Stover N.A., Jones T.A., Eddy S.R.,
RA Herrick G.A., Doak T.G., Wilson R.K., Mardis E.R., Landweber L.F.;
RT "The Oxytricha trifallax Macronuclear Genome: A Complex Eukaryotic Genome
RT with 16,000 Tiny Chromosomes.";
RL PLoS Biol. 11:E1001473-E1001473(2013).
CC -!- FUNCTION: Required for 60S pre-ribosomal subunits export to the
CC cytoplasm. {ECO:0000256|RuleBase:RU365057}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|RuleBase:RU365057}.
CC -!- SIMILARITY: Belongs to the SDA1 family.
CC {ECO:0000256|RuleBase:RU365057}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJY79642.1}.
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DR EMBL; AMCR01008468; EJY79642.1; -; Genomic_DNA.
DR AlphaFoldDB; J9IFM7; -.
DR EnsemblProtists; EJY79642; EJY79642; OXYTRI_23079.
DR OrthoDB; 5482564at2759; -.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0042273; P:ribosomal large subunit biogenesis; IEA:UniProtKB-UniRule.
DR GO; GO:0000055; P:ribosomal large subunit export from nucleus; IEA:UniProtKB-UniRule.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR027312; Sda1.
DR InterPro; IPR012977; SDA1_N.
DR PANTHER; PTHR12730; HSDA/SDA1-RELATED; 1.
DR PANTHER; PTHR12730:SF0; PROTEIN SDA1 HOMOLOG; 1.
DR Pfam; PF08158; SDA1_HEAT; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|RuleBase:RU365057};
KW Protein transport {ECO:0000256|RuleBase:RU365057};
KW Ribosome biogenesis {ECO:0000256|RuleBase:RU365057};
KW Transport {ECO:0000256|RuleBase:RU365057}.
FT DOMAIN 91..455
FT /note="SDA1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08158"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 556..689
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 703..748
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 760..800
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 564..627
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 628..657
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 658..682
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 703..725
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 773..793
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 800 AA; 93563 MW; 1E438D0E539A4FC5 CRC64;
MTKPSKKRSK SQQIAKSKPL QMTLSEEQKA QKAREDALKQ TLTLLQDRIK RQPELYKKEF
SLHFETFKKN LEDFKVNPGK RNEDVINYCL FFSHISAVFK EAIVEFLSSE LLNLLQQYYT
ILHPDNRMTM VTCLKILRGK DVVSPTLILP VFFKLFKCKD KELRNYLNAQ IIGDLKQLNK
THRNHGVNRK LQNFVFEMMQ DPNETATKRA LNVMIELYKR KIWNDDKTVN VIAQGCLHDN
PKVVASACKF FLVLDYVYES ESEDSSDDED KKLIMGRYKG TKKMTKNRMG KVDKAIKQHK
RKEKRRNKVK TFTDFLPIDL INDSQSFVEK MFNKLRKTND RYEVKLLMMR LISRMIGRHQ
LLLLQFYPHI IRYLQSHDKD KIGEIFAMII ESCHDLVPPE EIKPIVEKII SNYITEYCQN
QHITIGLNAI REILMRMPLA LDEAQIEYLC LFRTFKNSSV VASAKSLINY FRDVCPNLLP
KKYRGRFTKI DEDNSKENLV YGKVRTNFGI DGLDLLQKHQ GIEEGVNLAS TKILDDDDLR
KIRVLKLRQA VKKVDRKGFA SSDDEDEEGS ESGEEDSYDE EDESNQSQGD EEDVEDGSIE
EGSSIEYDSE EEGEEEEEED GEEQEEDEEI KSKSKSNLGK SEKLLGKRKK PMLDQSDLED
SDDMSEVEDN SLDIQSSELE EDSDDQANVH GFVYSHTLNT FRKTKRDKLD EQEKEKEATR
IEHKKKYLKN HDKKKGGETN KKKLKHKPFA MVKQKKLKAQ NDKLENTKTK LKKLKVQLGK
YKKNQKQKFE NKRKKQNRQT
//
