ID   J9J9C2_9SPIT            Unreviewed;       483 AA.
AC   J9J9C2;
DT   31-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   31-OCT-2012, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   RecName: Full=Histidine acid phosphatase family protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=OXYTRI_17914 {ECO:0000313|EMBL:EJY84345.1};
OS   Oxytricha trifallax.
OC   Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata; Spirotrichea;
OC   Stichotrichia; Sporadotrichida; Oxytrichidae; Oxytrichinae; Oxytricha.
OX   NCBI_TaxID=1172189 {ECO:0000313|EMBL:EJY84345.1};
RN   [1] {ECO:0000313|EMBL:EJY84345.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JRB310 {ECO:0000313|EMBL:EJY84345.1};
RX   PubMed=23382650; DOI=10.1371/journal.pbio.1001473;
RA   Swart E.C., Bracht J.R., Magrini V., Minx P., Chen X., Zhou Y.,
RA   Khurana J.S., Goldman A.D., Nowacki M., Schotanus K., Jung S., Fulton R.S.,
RA   Ly A., McGrath S., Haub K., Wiggins J.L., Storton D., Matese J.C.,
RA   Parsons L., Chang W.J., Bowen M.S., Stover N.A., Jones T.A., Eddy S.R.,
RA   Herrick G.A., Doak T.G., Wilson R.K., Mardis E.R., Landweber L.F.;
RT   "The Oxytricha trifallax Macronuclear Genome: A Complex Eukaryotic Genome
RT   with 16,000 Tiny Chromosomes.";
RL   PLoS Biol. 11:E1001473-E1001473(2013).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a phosphate monoester + H2O = an alcohol + phosphate;
CC         Xref=Rhea:RHEA:15017, ChEBI:CHEBI:15377, ChEBI:CHEBI:30879,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:67140; EC=3.1.3.2;
CC         Evidence={ECO:0000256|ARBA:ARBA00000032};
CC   -!- SIMILARITY: Belongs to the histidine acid phosphatase family.
CC       {ECO:0000256|ARBA:ARBA00005375}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EJY84345.1}.
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DR   EMBL; AMCR01004117; EJY84345.1; -; Genomic_DNA.
DR   AlphaFoldDB; J9J9C2; -.
DR   EnsemblProtists; EJY84345; EJY84345; OXYTRI_17914.
DR   OrthoDB; 5477542at2759; -.
DR   CDD; cd07061; HP_HAP_like; 1.
DR   Gene3D; 3.40.50.1240; Phosphoglycerate mutase-like; 1.
DR   InterPro; IPR033379; Acid_Pase_AS.
DR   InterPro; IPR000560; His_Pase_clade-2.
DR   InterPro; IPR029033; His_PPase_superfam.
DR   PANTHER; PTHR11567:SF110; ACID PHOSPHATASE 1, ISOFORM B; 1.
DR   PANTHER; PTHR11567; ACID PHOSPHATASE-RELATED; 1.
DR   Pfam; PF00328; His_Phos_2; 1.
DR   SUPFAM; SSF53254; Phosphoglycerate mutase-like; 1.
DR   PROSITE; PS00616; HIS_ACID_PHOSPHAT_1; 1.
PE   3: Inferred from homology;
SQ   SEQUENCE   483 AA;  55318 MW;  57168D782502F29C CRC64;
     MNNKSLNSMI RTRPAKSKMS NFTRQARAFT VLGLVLAATS TAKGIENKSF LQKTPDQDEL
     LMVVEVSRHG AREPSKILNF TADPNQNFNG TGNIMPLGKK QHFDLGQHMR QRYINDLKFL
     SANYTDNEVY VQTTYKQRTY LSSLYQLMGL YPDNQPPLSD YINYDIGRED YLSPIQKSGS
     IKPKVTTFNV VQIDAQADLL LHVDKDNCPR YAMTAQMTAQ SDEYAKVQKY FIDNFLDEFE
     RATNTSLSFK QMVEVCGYMQ WAELANLTLN FTPTASIDQY CLAMGDTKLY SVSYGLDELW
     KLGAFEFLNK LNYISNALKD GVQLKIKGRL PKLIHYAAHA ETLAAFFDGL GIHRVKRSFP
     GSALFFEIYK NSQDTIYVKL NYFHGDNRTL DVVKFPNQQE DTLSLSDFMN NLQKRLSQTN
     FTDVKNQCQN TNINTHPSDF YSGDKVLQEL EEAYQTQKMI QSETINIPDD ISTQPQKLFL
     KEE
//