ID J9S216_9ACTN Unreviewed; 613 AA.
AC J9S216;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Penicillin-binding protein transpeptidase {ECO:0000313|EMBL:AFR48686.1};
GN ORFNames=KTR9_2049 {ECO:0000313|EMBL:AFR48686.1};
OS Gordonia sp. KTR9.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Gordoniaceae;
OC Gordonia.
OX NCBI_TaxID=337191 {ECO:0000313|EMBL:AFR48686.1, ECO:0000313|Proteomes:UP000003281};
RN [1] {ECO:0000313|EMBL:AFR48686.1, ECO:0000313|Proteomes:UP000003281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KTR9 {ECO:0000313|EMBL:AFR48686.1,
RC ECO:0000313|Proteomes:UP000003281};
RX PubMed=22923396; DOI=10.1128/AEM.02120-12;
RA Chen H.P., Zhu S.H., Casabon I., Hallam S.J., Crocker F.H., Mohn W.W.,
RA Indest K.J., Eltis L.D.;
RT "Genomic and transcriptomic studies of an RDX (hexahydro-1,3,5-
RT trinitro-1,3,5-triazine)-degrading actinobacterium.";
RL Appl. Environ. Microbiol. 78:7798-7800(2012).
CC -!- SIMILARITY: Belongs to the transpeptidase family.
CC {ECO:0000256|ARBA:ARBA00007171}.
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DR EMBL; CP002907; AFR48686.1; -; Genomic_DNA.
DR RefSeq; WP_014926484.1; NC_018581.1.
DR AlphaFoldDB; J9S216; -.
DR STRING; 337191.KTR9_2049; -.
DR KEGG; gor:KTR9_2049; -.
DR PATRIC; fig|337191.3.peg.2342; -.
DR eggNOG; COG0768; Bacteria.
DR HOGENOM; CLU_025328_0_0_11; -.
DR Proteomes; UP000003281; Chromosome.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0046677; P:response to antibiotic; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR007887; MecA_N.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF24; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE PBPA; 1.
DR Pfam; PF05223; MecA_N; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..29
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 30..613
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5039372141"
FT DOMAIN 35..142
FT /note="NTF2-like N-terminal transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF05223"
FT DOMAIN 331..587
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 613 AA; 64192 MW; 70F3D942CC3A70A4 CRC64;
MWRMRTRWTP AVIVALCAAV TVATVGCSAS EDDGPRRAAE RFLQAYADRE VASAAALTDA
PGVAESAMES AWAGLGAEAL ESQAGRVRVT GDTAEVDVDY QWALPRGRDW TYDATLRMGR
SDDGWAVRWA STNIHPKLGA DQRLSLQIVE APRATVNEAD GSEVMVNGSV VGVNFDPVDA
AEQGASIAES VTAAVAVLRR FSPSLDEQTI TEQVTANRQQ YPLARLSHEQ FDRLRDQLAI
PGVVTNEQAE LVPEDPRFAP ALLTEVKKVV DSEVSGRAGW RVVTVNPNGL DADVLADHDP
DPAPAVSLSL SRTVQNAAQR AVNATNRFQI ALVAVQPSTG RILAVAQNPA ADRQGPIATT
GLYPPGSTFK MVTAAAAISR RMATPDTPVG CPGAIQIGPR LIPNYDGFSL GTVSMLRAFA
QSCNTTFAKL ASQMGPSDLA HAAAAMGIGQ QYEIAGLDAV SGSVPIENEL VARSEDGFGQ
GKVLVSPLGL ALVAATVANG TKAPVPQLIL DKPTKVEGPT PTMAPEVYDQ LRPMMRAVIT
SGTASVIDGQ GAVFGKTGEA EFAGGSHAWF AGYRGDIAFA TLVVGGGDSN NAVAVTRDFF
GGLGPGYAVR PLP
//
