ID J9S9I2_9ACTN Unreviewed; 505 AA.
AC J9S9I2;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Succinate-semialdehyde dehydrogenase {ECO:0000313|EMBL:AFR50616.1};
GN ORFNames=KTR9_4007 {ECO:0000313|EMBL:AFR50616.1};
OS Gordonia sp. KTR9.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Gordoniaceae;
OC Gordonia.
OX NCBI_TaxID=337191 {ECO:0000313|EMBL:AFR50616.1, ECO:0000313|Proteomes:UP000003281};
RN [1] {ECO:0000313|EMBL:AFR50616.1, ECO:0000313|Proteomes:UP000003281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KTR9 {ECO:0000313|EMBL:AFR50616.1,
RC ECO:0000313|Proteomes:UP000003281};
RX PubMed=22923396; DOI=10.1128/AEM.02120-12;
RA Chen H.P., Zhu S.H., Casabon I., Hallam S.J., Crocker F.H., Mohn W.W.,
RA Indest K.J., Eltis L.D.;
RT "Genomic and transcriptomic studies of an RDX (hexahydro-1,3,5-
RT trinitro-1,3,5-triazine)-degrading actinobacterium.";
RL Appl. Environ. Microbiol. 78:7798-7800(2012).
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00009986, ECO:0000256|RuleBase:RU003345}.
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DR EMBL; CP002907; AFR50616.1; -; Genomic_DNA.
DR RefSeq; WP_014928067.1; NC_018581.1.
DR AlphaFoldDB; J9S9I2; -.
DR STRING; 337191.KTR9_4007; -.
DR KEGG; gor:KTR9_4007; -.
DR PATRIC; fig|337191.3.peg.4395; -.
DR eggNOG; COG1012; Bacteria.
DR HOGENOM; CLU_005391_5_1_11; -.
DR Proteomes; UP000003281; Chromosome.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd07103; ALDH_F5_SSADH_GabD; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR PANTHER; PTHR43353; SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43353:SF5; SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003345}.
FT DOMAIN 29..497
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 266
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 505 AA; 52668 MW; 23000DA88AB45D78 CRC64;
MTAPAPVTPH NAPEAVSRVN TDLFIGGTWT PAASGERFDV VNPATGDVLA RVADADAVDA
RHALETAAAH QAGWAATSPR SRSEILYRAH RLIMDRVDGI AAVMTAEMGK PLAEAKGEVA
YGAEFFRWFA EEAVRIGGDS TTTGDGSHRI VVTRQPVGPC ILITPWNFPL AMGTRKIGPA
IAAGCTMVLK PAELTPLTTL LLADILVEAG LPPGVLNVVT TSDPSTVVTE WMESGLARKI
SFTGSTEVGK LLLRQAAGTV MRTSMELGGN APFIVCADAD IPRAVDGLMF AKMRNIGQAC
TAANRVFVHR SVIDEFTAAF AAKMAGLRVG DGAADNVQVG PLVERAAVEK VSTLVSDAVA
KGATVVCGGE NPEGPGFFYP PTVLTGVGLD ADLMRTEIFG PVAAIVPFGN AYEPDDPAAD
DEVIALANDT PWGLVGYLFS QDVDRCARLS AALETGMVGV NTGAVSNPAA PFGGVKESGL
GREGGRVGLE EFLDMKYTAT PIPLR
//
