ID J9VHB5_CRYNH Unreviewed; 901 AA.
AC J9VHB5;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=Pentatricopeptide repeat domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CNAG_00643 {ECO:0000313|EMBL:AFR92771.1};
OS Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 /
OS CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Cryptococcus;
OC Cryptococcus neoformans species complex.
OX NCBI_TaxID=235443 {ECO:0000313|EMBL:AFR92771.1, ECO:0000313|Proteomes:UP000010091};
RN [1] {ECO:0000313|EMBL:AFR92771.1, ECO:0000313|Proteomes:UP000010091}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H99 / ATCC 208821 / CBS 10515 / FGSC 9487
RC {ECO:0000313|Proteomes:UP000010091};
RX PubMed=24743168; DOI=10.1371/journal.pgen.1004261;
RA Janbon G., Ormerod K.L., Paulet D., Byrnes E.J.III., Yadav V.,
RA Chatterjee G., Mullapudi N., Hon C.C., Billmyre R.B., Brunel F., Bahn Y.S.,
RA Chen W., Chen Y., Chow E.W., Coppee J.Y., Floyd-Averette A., Gaillardin C.,
RA Gerik K.J., Goldberg J., Gonzalez-Hilarion S., Gujja S., Hamlin J.L.,
RA Hsueh Y.P., Ianiri G., Jones S., Kodira C.D., Kozubowski L., Lam W.,
RA Marra M., Mesner L.D., Mieczkowski P.A., Moyrand F., Nielsen K., Proux C.,
RA Rossignol T., Schein J.E., Sun S., Wollschlaeger C., Wood I.A., Zeng Q.,
RA Neuveglise C., Newlon C.S., Perfect J.R., Lodge J.K., Idnurm A.,
RA Stajich J.E., Kronstad J.W., Sanyal K., Heitman J., Fraser J.A.,
RA Cuomo C.A., Dietrich F.S.;
RT "Analysis of the genome and transcriptome of Cryptococcus neoformans var.
RT grubii reveals complex RNA expression and microevolution leading to
RT virulence attenuation.";
RL PLoS Genet. 10:E1004261-E1004261(2014).
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DR EMBL; CP003820; AFR92771.1; -; Genomic_DNA.
DR RefSeq; XP_012046855.1; XM_012191465.1.
DR AlphaFoldDB; J9VHB5; -.
DR GeneID; 23884426; -.
DR KEGG; cng:CNAG_00643; -.
DR VEuPathDB; FungiDB:CNAG_00643; -.
DR HOGENOM; CLU_014664_0_0_1; -.
DR OrthoDB; 1406903at2759; -.
DR Proteomes; UP000010091; Chromosome 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR002885; Pentatricopeptide_rpt.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR47942:SF63; ATPASE EXPRESSION PROTEIN 3; 1.
DR PANTHER; PTHR47942; TETRATRICOPEPTIDE REPEAT (TPR)-LIKE SUPERFAMILY PROTEIN-RELATED; 1.
DR Pfam; PF01535; PPR; 1.
PE 4: Predicted;
FT REGION 871..901
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 901 AA; 100590 MW; E462EE5F6DFB19D3 CRC64;
MLRPSIARKV ARIRHARIAC RTLHTLDTHF PSFDSLSDKN ITQNSSESRF PLYRPQQHAQ
EIPLTADTLA ALPSEQALSR QLKRRVTQKA IENLPEFTED ELRDFYATLV KSGSKDNGGI
YQALEAPSET KKIPMPKKER EEILTDMAGR LVGERGLALL KDPARYGKSL ELVVNGSKSS
DAPYAILDIL SQAAILSGPS ETSKGKAVEG QLPLRSLEVP LGLVTSKEWD ALFQEFIRKG
DAAAAESLLD IMDAHGVPVG IERINSVIHA YARKGRSEDV ARLTLDVTAM GETISSDQQD
DYILSILRQT PSNPGPAIAR LRQAELAGTP FPQSSYQVVI SHLTSPSSIV QPNSHTRAVA
WDLFAHMRLT AHPTPTRELY TTMIKSCGEA SQPEPERARD LWIEMTEQEK IEPSTEAYNA
IIRSLGSTKK DYLEAFDLLR QMLVKHNDAV FVPFEEEDGI PRFSEYVPTL KTFASVLEGT
KRAGDVNRAR WVLSEVIKLS RAGQALNVPK WKEGPSGDLM AAVFMTYAAW NPVLRKREVK
MRKASETPYG EASETMVAEK EEHRLPKGEE FLNVDLLQDV VEPPSAGSSS IDYTLEEPPV
NDFFTPLSSA DAIRECTSLF HRVLSDIQSS SSTSDFLPFR HVYITPKLIN SYISVYNAHG
PSLSSVKGVY DTVWEEASSV SGRSVRPNAW TFIPLLEKCA SGSRGGIYPA DRSLALSWGR
ALWSSYLAFF KSASSELASV PSSEHLTIQR RKYLLGLGDR QIERIWKAVI KLEALHGDVD
EAMKLLEEFH ATYKPDAITQ LYAPLPEVGL QLKMFTPAMT PEADVPPLLL FDDIKPLHQR
LVREGRARDI KKVKWIAAGY EKSLKTRKGW RMKGVGQKRE KSRAKDLERL VAQQGEMERL
E
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