ID J9VSM1_CRYNH Unreviewed; 556 AA.
AC J9VSM1;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 13-NOV-2013, sequence version 2.
DT 13-SEP-2023, entry version 36.
DE RecName: Full=WH2 domain-containing protein {ECO:0000259|PROSITE:PS51082};
GN ORFNames=CNAG_02201 {ECO:0000313|EMBL:AFR95619.2};
OS Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 /
OS CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Cryptococcus;
OC Cryptococcus neoformans species complex.
OX NCBI_TaxID=235443 {ECO:0000313|EMBL:AFR95619.2, ECO:0000313|Proteomes:UP000010091};
RN [1] {ECO:0000313|EMBL:AFR95619.2, ECO:0000313|Proteomes:UP000010091}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H99 / ATCC 208821 / CBS 10515 / FGSC 9487
RC {ECO:0000313|Proteomes:UP000010091};
RX PubMed=24743168; DOI=10.1371/journal.pgen.1004261;
RA Janbon G., Ormerod K.L., Paulet D., Byrnes E.J.III., Yadav V.,
RA Chatterjee G., Mullapudi N., Hon C.C., Billmyre R.B., Brunel F., Bahn Y.S.,
RA Chen W., Chen Y., Chow E.W., Coppee J.Y., Floyd-Averette A., Gaillardin C.,
RA Gerik K.J., Goldberg J., Gonzalez-Hilarion S., Gujja S., Hamlin J.L.,
RA Hsueh Y.P., Ianiri G., Jones S., Kodira C.D., Kozubowski L., Lam W.,
RA Marra M., Mesner L.D., Mieczkowski P.A., Moyrand F., Nielsen K., Proux C.,
RA Rossignol T., Schein J.E., Sun S., Wollschlaeger C., Wood I.A., Zeng Q.,
RA Neuveglise C., Newlon C.S., Perfect J.R., Lodge J.K., Idnurm A.,
RA Stajich J.E., Kronstad J.W., Sanyal K., Heitman J., Fraser J.A.,
RA Cuomo C.A., Dietrich F.S.;
RT "Analysis of the genome and transcriptome of Cryptococcus neoformans var.
RT grubii reveals complex RNA expression and microevolution leading to
RT virulence attenuation.";
RL PLoS Genet. 10:E1004261-E1004261(2014).
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DR EMBL; CP003825; AFR95619.2; -; Genomic_DNA.
DR RefSeq; XP_012049812.1; XM_012194422.1.
DR AlphaFoldDB; J9VSM1; -.
DR GeneID; 23885856; -.
DR KEGG; cng:CNAG_02201; -.
DR VEuPathDB; FungiDB:CNAG_02201; -.
DR HOGENOM; CLU_547473_0_0_1; -.
DR OrthoDB; 1452033at2759; -.
DR Proteomes; UP000010091; Chromosome 6.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR InterPro; IPR003882; Pistil_extensin.
DR InterPro; IPR003124; WH2_dom.
DR Pfam; PF02205; WH2; 1.
DR PRINTS; PR01218; PSTLEXTENSIN.
DR PROSITE; PS51082; WH2; 1.
PE 4: Predicted;
FT DOMAIN 1..18
FT /note="WH2"
FT /evidence="ECO:0000259|PROSITE:PS51082"
FT REGION 1..556
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 48..62
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 102..279
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 308..368
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 386..455
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 456..494
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 497..511
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 556 AA; 54969 MW; 80771A377A061CA6 CRC64;
MNAALLQQIQ QGKGLKKTHV NDRSAPQVAG SVAGAAGGAG GAAATGRPPA APRPPASAPP
VPSGNDPASQ LAGLFAGGMP ALRKTGDRAA SGTGHFAKPP PVPSASKAPS KPSAPPPPPP
PPSAPPAPPA PSGPPSRTAP PAPPPPPAPP GPSRTAPSAP PPPPPPPAPP APSRHVPAPP
ARATPPAPPA PPAPSRTAPP APPAPPAPPA PPARVHRKEP PAPPPLPGRS PAPSLPNRPT
SSVPGRAVPP PPPRPSSTAS GRAPPPPPPP RPTGPPTLPS RPASSYATPN RALPPAIPSR
TDSSNLAPPT PPRRPSSVSM SAPPAPPAPP APPTPPAPPA PAARRMIPPP APAPTRPIPP
PAPRVIQPEP EPEQYYGEEE EETAPPPLPA GRPASRLPAP PSAPPPPPPP GPSPASRAAP
PAPARAPPSP APDRTRPHPA GTTFAPPPPP PGISPAATSR SSLAPPILAS RPRPTSQNRT
TPAAQHSYSS DAVDSDGGTD ADADGDDGAE DQVPEPPAVV GSWTFPMKGM FPAPRPWSGG
RKTYVSGNMQ GGGIGF
//
