ID K0HZV2_9BURK Unreviewed; 310 AA.
AC K0HZV2;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Ribosomal RNA large subunit methyltransferase N {ECO:0000313|EMBL:AFU45410.1};
GN ORFNames=C380_08540 {ECO:0000313|EMBL:AFU45410.1};
OS Acidovorax sp. KKS102.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Acidovorax.
OX NCBI_TaxID=358220 {ECO:0000313|EMBL:AFU45410.1, ECO:0000313|Proteomes:UP000006306};
RN [1] {ECO:0000313|EMBL:AFU45410.1, ECO:0000313|Proteomes:UP000006306}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KKS102 {ECO:0000313|EMBL:AFU45410.1,
RC ECO:0000313|Proteomes:UP000006306};
RX PubMed=23209225; DOI=10.1128/JB.01848-12;
RA Ohtsubo Y., Maruyama F., Mitsui H., Nagata Y., Tsuda M.;
RT "Complete Genome Sequence of Acidovorax sp. Strain KKS102, a
RT Polychlorinated-Biphenyl Degrader.";
RL J. Bacteriol. 194:6970-6971(2012).
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SIMILARITY: Belongs to the radical SAM superfamily. RlmN family.
CC {ECO:0000256|ARBA:ARBA00007544}.
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DR EMBL; CP003872; AFU45410.1; -; Genomic_DNA.
DR RefSeq; WP_015013441.1; NC_018708.1.
DR AlphaFoldDB; K0HZV2; -.
DR STRING; 358220.C380_08540; -.
DR KEGG; ack:C380_08540; -.
DR PATRIC; fig|358220.3.peg.1732; -.
DR eggNOG; COG0820; Bacteria.
DR HOGENOM; CLU_899761_0_0_4; -.
DR OrthoDB; 8477961at2; -.
DR Proteomes; UP000006306; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0006364; P:rRNA processing; IEA:InterPro.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR040072; Methyltransferase_A.
DR InterPro; IPR004383; rRNA_lsu_MTrfase_RlmN/Cfr.
DR InterPro; IPR007197; rSAM.
DR PANTHER; PTHR30544; 23S RRNA METHYLTRANSFERASE; 1.
DR PANTHER; PTHR30544:SF5; RADICAL SAM CORE DOMAIN-CONTAINING PROTEIN; 1.
DR PIRSF; PIRSF006004; CHP00048; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:AFU45410.1};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:AFU45410.1}.
FT DOMAIN 35..251
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 310 AA; 34776 MW; 27DE91434426014E CRC64;
MQVKRIDSSD ENVSKYVFDF GNAVAEAVLY KYPTYEDRTV ICCSTQSGCP VGCRFCGAGD
AFVRSLTGDE IVAQVQHLFA DRGIDPEAVQ RCQIMFMSMG EPLLNFGGLS DAIRKLHALY
PRFALLISTS APDVDYERVR DLSVEVPTVG LQFSVHESTD EARNALIPFK AKLTLAQIAK
EGELWFRATG REPFFNYCAH DRNTSHEDAE RIYQIFNPMF WQATISVVCE RDESVAAANI
RQRQLATDFM EKLNAYGYPT RCFDPAGQDD IGGGCGQLWF VQEWMRNNPE LARPSIGRSI
PIVHAPRCTA
//
