ID K0JVL9_SACES Unreviewed; 874 AA.
AC K0JVL9;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN OrderedLocusNames=BN6_09180 {ECO:0000313|EMBL:CCH28248.1};
OS Saccharothrix espanaensis (strain ATCC 51144 / DSM 44229 / JCM 9112 / NBRC
OS 15066 / NRRL 15764).
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharothrix.
OX NCBI_TaxID=1179773 {ECO:0000313|EMBL:CCH28248.1, ECO:0000313|Proteomes:UP000006281};
RN [1] {ECO:0000313|EMBL:CCH28248.1, ECO:0000313|Proteomes:UP000006281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51144 / DSM 44229 / JCM 9112 / NBRC 15066 / NRRL 15764
RC {ECO:0000313|Proteomes:UP000006281};
RX PubMed=22958348; DOI=10.1186/1471-2164-13-465;
RA Strobel T., Al-Dilaimi A., Blom J., Gessner A., Kalinowski J.,
RA Luzhetska M., Puhler A., Szczepanowski R., Bechthold A., Ruckert C.;
RT "Complete genome sequence of Saccharothrix espanaensis DSM 44229T and
RT comparison to the other completely sequenced Pseudonocardiaceae.";
RL BMC Genomics 13:465-465(2012).
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DR EMBL; HE804045; CCH28248.1; -; Genomic_DNA.
DR AlphaFoldDB; K0JVL9; -.
DR STRING; 1179773.BN6_09180; -.
DR KEGG; sesp:BN6_09180; -.
DR PATRIC; fig|1179773.3.peg.923; -.
DR eggNOG; COG0513; Bacteria.
DR eggNOG; COG3064; Bacteria.
DR HOGENOM; CLU_003041_27_0_11; -.
DR Proteomes; UP000006281; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR CDD; cd00268; DEADc; 1.
DR CDD; cd18787; SF2_C_DEAD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000629; RNA-helicase_DEAD-box_CS.
DR InterPro; IPR014014; RNA_helicase_DEAD_Q_motif.
DR PANTHER; PTHR47963:SF8; ATP-DEPENDENT RNA HELICASE DEAD; 1.
DR PANTHER; PTHR47963; DEAD-BOX ATP-DEPENDENT RNA HELICASE 47, MITOCHONDRIAL; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00039; DEAD_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS51195; Q_MOTIF; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:CCH28248.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000006281}.
FT DOMAIN 98..126
FT /note="DEAD-box RNA helicase Q"
FT /evidence="ECO:0000259|PROSITE:PS51195"
FT DOMAIN 129..300
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 328..474
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..37
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 496..874
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 98..126
FT /note="Q motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00552"
FT COMPBIAS 572..586
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 708..722
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 750..764
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 808..863
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 874 AA; 92314 MW; C1CA41ECF56899EF CRC64;
MPRADYGGTV PPGEGARIPR RPSRATRPAA SRGREAVGAV EWPVQAVRAG TREAIILTAT
NEQTQLDPVA LEHSELGVPD VDTSHPLVAN APVRTDSPTF AELGVHAEIV RALAEAGIER
AFAIQELTLP LALAGDDVIG QARTGTGKTL GFGIPLLQRI TVPGDGTPQA LVVVPTRELC
LQVTHDLTDA AKHLGVRVMA IYGGRPYEPQ INALRKGVDL VVGTPGRLLD LAEQRHLVLG
KVRGLVLDEA DEMLDLGFLP DIERILRMVP DERQTMLFSA TMPGPIITLA RTFLNQPTHV
RAEENDAGAI HERTEQFVYR AHALDKTELL ARALQARDRG LCMIFTRTKR TAQKVADEMV
ERGFAAAAVH GDLGQGAREQ ALRAFRSGKI DVLVATDVAA RGIDVEGVTH VINYQCPEDE
KTYVHRIGRT GRAGRTGVAV TLVDWDEMPR WKSISDALNL GKPEPVETYS TSDHLFAELH
IPAGSTGRLP LGLRTRAGLD AEPEENLKGE RKPRKRGRKR GAPGSPGSPT TSGEPAATED
GTENGGGRTR RRRRSRGGVP AEGVTAEGGS PNGQAEGGSP NGEAGSTEHT RSRRRRRRGS
SAGEAAAVAD GSAPEAVAVN GTAVEHAPVE AATPAEAVAI PDAPKAEAPA DAAPTRSRRR
SRAGASTDAP ADAAPQAPAA DAVAAPVAEP VAAPVAEAPA EAPAEAVTPR RTRTRKKAEP
APAEAVTEPA AEPVAEPVAE PVAEPVAEAA PKRTRTRKKA VEAPAEATPA DAEPAVETAV
EPAAPKRART RKAAAPAEVA ETSDQPAEAA PKRTRTRKTA EATAEAQPEE ADTRSRTRRK
AEPADAEETE RPRTRRRATR TETEGSADAP PSAD
//
