ID K0K4C8_SACES Unreviewed; 468 AA.
AC K0K4C8;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Putative histidine kinase {ECO:0000313|EMBL:CCH31714.1};
GN OrderedLocusNames=BN6_44330 {ECO:0000313|EMBL:CCH31714.1};
OS Saccharothrix espanaensis (strain ATCC 51144 / DSM 44229 / JCM 9112 / NBRC
OS 15066 / NRRL 15764).
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharothrix.
OX NCBI_TaxID=1179773 {ECO:0000313|EMBL:CCH31714.1, ECO:0000313|Proteomes:UP000006281};
RN [1] {ECO:0000313|EMBL:CCH31714.1, ECO:0000313|Proteomes:UP000006281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51144 / DSM 44229 / JCM 9112 / NBRC 15066 / NRRL 15764
RC {ECO:0000313|Proteomes:UP000006281};
RX PubMed=22958348; DOI=10.1186/1471-2164-13-465;
RA Strobel T., Al-Dilaimi A., Blom J., Gessner A., Kalinowski J.,
RA Luzhetska M., Puhler A., Szczepanowski R., Bechthold A., Ruckert C.;
RT "Complete genome sequence of Saccharothrix espanaensis DSM 44229T and
RT comparison to the other completely sequenced Pseudonocardiaceae.";
RL BMC Genomics 13:465-465(2012).
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DR EMBL; HE804045; CCH31714.1; -; Genomic_DNA.
DR AlphaFoldDB; K0K4C8; -.
DR STRING; 1179773.BN6_44330; -.
DR KEGG; sesp:BN6_44330; -.
DR PATRIC; fig|1179773.3.peg.4441; -.
DR eggNOG; COG4585; Bacteria.
DR HOGENOM; CLU_000445_20_2_11; -.
DR BioCyc; SESP1179773:BN6_RS21465-MONOMER; -.
DR Proteomes; UP000006281; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR Gene3D; 1.20.5.1930; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR025828; Put_sensor_dom.
DR InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR PANTHER; PTHR24421:SF10; SENSORY TRANSDUCTION HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF07730; HisKA_3; 1.
DR Pfam; PF13796; Sensor; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:CCH31714.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006281};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 68..88
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 94..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 162..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 215..236
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 378..468
FT /note="Histidine kinase/HSP90-like ATPase"
FT /evidence="ECO:0000259|SMART:SM00387"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 468 AA; 49720 MW; 77915890BCFF9420 CRC64;
MEPRHGWRTP AGPQGSDRPL VRRTPSAGLP WVTWSFEETG EHGVSGENAR VGRWAGLRHR
LRDAIRSCGY LVVGFGTSLV SLLALTVLPA LTVVLGLLLV GVFGIPRLAG ALRVLIGFDR
RRVARYLGVE VPVPYRPLEG PASVRLATTL SDPATRRDLV WLLFHAVVGI PLGIIGLTLS
LGTVFGLTIP LWWYLLPADK PVSMIHQITS WPTALSSFGQ GVAYVVIALL IAPPLARLHA
RVGRRLLSPG RGGRVRLAEQ VARLSVSRAA ALDAHGMELR RIEGALHDDT QNRIVAVSMH
LGMVESALRR DPETALPLVL RAQDAATDAL AGLREVVRGI YPPILADRGL DGALTSLASH
SGVPCELDVV DVPRAPTAVE AAAYYVVSEA LTNVSKHSGA RSVRVRVAGA KGNLRITVTD
DGLGGAAEGQ GRGLTGMRRR VEAFSGAMSL TSPPGGPTVL EVVLPCAS
//
