ID   K0NS39_DESTT            Unreviewed;      1345 AA.
AC   K0NS39;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   27-MAR-2024, entry version 55.
DE   SubName: Full=HrpA: ATP-dependent RNA helicase {ECO:0000313|EMBL:CCK81797.1};
DE            EC=3.6.1.- {ECO:0000313|EMBL:CCK81797.1};
GN   Name=hrpA {ECO:0000313|EMBL:CCK81797.1};
GN   OrderedLocusNames=TOL2_C36400 {ECO:0000313|EMBL:CCK81797.1};
OS   Desulfobacula toluolica (strain DSM 7467 / Tol2).
OC   Bacteria; Thermodesulfobacteriota; Desulfobacteria; Desulfobacterales;
OC   Desulfobacteraceae; Desulfobacula.
OX   NCBI_TaxID=651182 {ECO:0000313|EMBL:CCK81797.1, ECO:0000313|Proteomes:UP000007347};
RN   [1] {ECO:0000313|EMBL:CCK81797.1, ECO:0000313|Proteomes:UP000007347}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 7467 / Tol2 {ECO:0000313|Proteomes:UP000007347};
RX   PubMed=23088741; DOI=10.1111/j.1462-2920.2012.02885.x;
RA   Wohlbrand L., Jacob J.H., Kube M., Mussmann M., Jarling R., Beck A.,
RA   Amann R., Wilkes H., Reinhardt R., Rabus R.;
RT   "Complete genome, catabolic sub-proteomes and key-metabolites of
RT   Desulfobacula toluolica Tol2, a marine, aromatic compound-degrading,
RT   sulfate-reducing bacterium.";
RL   Environ. Microbiol. 15:1334-55(2013).
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DR   EMBL; FO203503; CCK81797.1; -; Genomic_DNA.
DR   RefSeq; WP_014958985.1; NC_018645.1.
DR   STRING; 651182.TOL2_C36400; -.
DR   KEGG; dto:TOL2_C36400; -.
DR   PATRIC; fig|651182.5.peg.4276; -.
DR   HOGENOM; CLU_001832_3_3_7; -.
DR   OrthoDB; 9805617at2; -.
DR   Proteomes; UP000007347; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR   CDD; cd18791; SF2_C_RHA; 1.
DR   Gene3D; 1.20.120.1080; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR007502; Helicase-assoc_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR024590; HrpA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010222; RNA_helicase_HrpA.
DR   NCBIfam; TIGR01967; DEAH_box_HrpA; 1.
DR   PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR   PANTHER; PTHR18934:SF83; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF11898; DUF3418; 1.
DR   Pfam; PF21010; HA2_C; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF07717; OB_NTP_bind; 1.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00847; HA2; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000313|EMBL:CCK81797.1};
KW   Hydrolase {ECO:0000313|EMBL:CCK81797.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007347}.
FT   DOMAIN          88..251
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          285..450
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
SQ   SEQUENCE   1345 AA;  152699 MW;  3605397145E4A395 CRC64;
     MKKLKKIESL CSNVMLKDKH AVLKELRAIK KLKPNSPCSL EIHAKKTKLL FEKTQRSAQQ
     TRSRLSNKPS HIVFNPDLPI THKKDDIICA IKNNSVVIIS GETGSGKTTQ IPKFCLEAGR
     GIKGLIGCTQ PRRIAAVNVA RRIAEELNEN IGKSVGYKIR FDDKTNANAY IKMMTDGILL
     AETQADRFLS AYDTIIVDEA HERSLNIDFT LGILRRLVRQ RKDLKLIITS ATIDTQKFSK
     AFDNAPIIEV SGRMYPVETL YRPFLDEDSE KHSFEDQGYV EAAADAVHLL LSQSRSGDIL
     VFMPTEQDIG ETMELIRGKQ HPGVTVLPLF ARLSAQEQSK IFSRQVGRKV IVSTNVAETS
     LTIPGIKYVV DTGLARIPSY SPRTRTTSLP VSPISQSSAN QRLGRCGRVE NGICIRLFDE
     DDFGARPFFT SPEILRSNLA EVILRMIALN LGDVSTFPFI DAPAPKSVKD GFDTLIELGA
     IKEKTTKHKT AKKKEYTLTK IGLIMAKLPI DPKLSRILIE ADTKGCLAEA VIITTALAIS
     DPRQRPAEKT QAADQQHAMF KDPGSDFITI LNIWNAVKAA EKKLNSRSKL KKFCQDHFLS
     FKRLREWTDI HGQIVRILKE HGIRGEKKID FQTGTQGMKS KEFNLGGPLY IALHQSLLSG
     YLANIAHKKE KNIFSAAKGQ QAMIFPGSGL FNTAGNWIVA AEFVKTSQLF ARSVATIDPE
     WLEPIAKDLC AHTYCDPHWE KKRGQVIAKE QVSLFGLIIV DGRNIAYGKI NPEESGEIFI
     RHALVQGEIH QQFEFMTHNR QLIDQLETLE HKTRRKDILA SEDDMYLFYQ SRLPKHFYNI
     RTFSKFIKDQ KNQDFLKMTL EDLQQSFVDE TELCLFPDAL TMEQGKFKLE YEFNPGSQKD
     GVTLKVPAAS AAMVSKNSVD RLIPGLFENK IAALIKALPK KYRVKLVPVS EKAAIIAKEM
     PEQDKPLYSQ LSSFIQKRFD LVIPATLWSD KELPDHLKMR ISIRDKKGKE IKAIRDKSVL
     NEFYSNLAPQ KGNSFHAAQK KYELSPVKEW NFKDLEDVII IDQNPDFMQK AYPGLQIETK
     TGTKNDTIVL SLRLFKSEQA AQTAHCKGIN ALFQLCFPDD FKALKKDINI SSQIKQMAPF
     FNGQTKFQQS LFNLITTTVF AKNIRTKKEF ETHAQKQLKL LYHTGRQFIK IISTLGKEYQ
     ACFELIQKLS FQHQKKKKTF DILTALFKDL KNIVPENFLD LYTMERIEDL HRYVACIRIR
     AQKSVDNPLK EEKKALQTAG YTKHLNQLLS SLSQDSSTEK SQQVEDFFWL IEEYKISLFA
     QELKTKVKIS AKKLDQFLIR LSTMI
//