ID K0T6D1_THAOC Unreviewed; 1194 AA.
AC K0T6D1;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 24-JAN-2024, entry version 45.
DE RecName: Full=Structural maintenance of chromosomes protein {ECO:0000256|PIRNR:PIRNR005719};
GN ORFNames=THAOC_13093 {ECO:0000313|EMBL:EJK66002.1};
OS Thalassiosira oceanica (Marine diatom).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Bacillariophyta;
OC Coscinodiscophyceae; Thalassiosirophycidae; Thalassiosirales;
OC Thalassiosiraceae; Thalassiosira.
OX NCBI_TaxID=159749 {ECO:0000313|EMBL:EJK66002.1, ECO:0000313|Proteomes:UP000266841};
RN [1] {ECO:0000313|EMBL:EJK66002.1, ECO:0000313|Proteomes:UP000266841}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP1005 {ECO:0000313|EMBL:EJK66002.1,
RC ECO:0000313|Proteomes:UP000266841};
RX PubMed=22835381; DOI=10.1186/gb-2012-13-7-r66;
RA Lommer M., Specht M., Roy A.S., Kraemer L., Andreson R., Gutowska M.A.,
RA Wolf J., Bergner S.V., Schilhabel M.B., Klostermeier U.C., Beiko R.G.,
RA Rosenstiel P., Hippler M., Laroche J.;
RT "Genome and low-iron response of an oceanic diatom adapted to chronic iron
RT limitation.";
RL Genome Biol. 13:R66-R66(2012).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PIRNR:PIRNR005719}.
CC -!- SIMILARITY: Belongs to the SMC family. SMC2 subfamily.
CC {ECO:0000256|ARBA:ARBA00005231}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJK66002.1}.
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DR EMBL; AGNL01015327; EJK66002.1; -; Genomic_DNA.
DR AlphaFoldDB; K0T6D1; -.
DR EnsemblProtists; EJK66002; EJK66002; THAOC_13093.
DR eggNOG; KOG0933; Eukaryota.
DR OMA; HNKIAME; -.
DR Proteomes; UP000266841; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
DR CDD; cd03273; ABC_SMC2_euk; 1.
DR Gene3D; 1.20.1060.20; -; 1.
DR Gene3D; 1.20.5.340; -; 1.
DR Gene3D; 3.30.70.1620; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003395; RecF/RecN/SMC_N.
DR InterPro; IPR024704; SMC.
DR InterPro; IPR027120; Smc2_ABC.
DR InterPro; IPR010935; SMC_hinge.
DR InterPro; IPR036277; SMC_hinge_sf.
DR PANTHER; PTHR43977:SF2; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN; 1.
DR PANTHER; PTHR43977; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3; 1.
DR Pfam; PF06470; SMC_hinge; 1.
DR Pfam; PF02463; SMC_N; 1.
DR PIRSF; PIRSF005719; SMC; 1.
DR SMART; SM00968; SMC_hinge; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF75553; Smc hinge domain; 1.
DR SUPFAM; SSF57997; Tropomyosin; 2.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW DNA condensation {ECO:0000256|ARBA:ARBA00023067};
KW Nucleus {ECO:0000256|PIRNR:PIRNR005719};
KW Reference proteome {ECO:0000313|Proteomes:UP000266841}.
FT DOMAIN 521..643
FT /note="SMC hinge"
FT /evidence="ECO:0000259|SMART:SM00968"
FT REGION 1152..1194
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 246..294
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 352..502
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 763..888
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1152..1174
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1194 AA; 132037 MW; AA054CCC26EEFE56 CRC64;
MHIKEIVVDG FKSYAHRTVI AGFDPHFNAI TGLNGSGKSN ILDSICFVLG ITNLSQVRAG
NLSELVYKQG QAGVNKASVT IVFDNEDESS SPVGYEQCKE VNVTRQVLIG GKSKYLINGR
NSPAGQVANL FHSVQLNVNN PHFLIMQGRI TKVLNMKPKE ILGMVEEAAG TRMYENKKNT
AVKTIEKKQM KVDEINSILS EEITPTLERL RGEKQQYLKW SKNNADIERI ERFVVASEYV
AAMDTLSKNS EDVAQMEAEV AKHEEILRTA RDGVQAKEEE MDKLSKEMNC DLETSHNEAK
ADEETKSKNL VKATSAWENK KLAVASAAKE VKEAEVAVAE SKGAVASMKK SAANKMSAIR
QAKDEAVEAE ENLARLQTEY QNMCAGISSE EGDEGRTLPD QISKAYSDAN TAEAKAKQAQ
MKIDHLSKTL KSVEKDMKKE KSSAAKLSKK RDTTVEKVDA LRSKLSKIDF SEKDFNSLEN
EKFELENVVS TLQEKVDTLS AQLEGRLAFN YSDPVRGFDR SKVKGLVARL INVKVPKHST
ALEIVAGGKL YQVVVDEATT GKALLDKGKL QRRVTIIPLD KIVPRRVSSS TVDRASSMAK
DMDTTSQPAI ELVGFDEEVR NAIEHVFGST LVVDGMNAAN SICDATKTRT VTLDGDVYEP
SGLISGGSKD NLGSTLSKIS QLTMASNELK EKTSRGELDI ATSELAAVEK HISQTSYGML
KDKFDSMKKE VSEATDEVSQ MLKTKDEKWA LHKELKEKET QLTEDREKRL KEIEARVEEA
KQTVVDKENA AREAENKSQA LDMEMQSSEE DVKAAEEAVT VAMEALDAAK EDEAKYEMKA
GELKAIWEEA RASLDDMDKR LKACSEELGA LSKEKSKLIK KAESAEIEGK KISVKISKFH
TEHSKAERFV KSMMNKYAWI ETEKDAFGIA GGDYDFEETN PEAMSKHLKG LQAEQTSLAK
KINKKVMGMI EKAEGEYTEL LRKRKVVEND KKKIETVIEN LDIKKKVELE RTWTKVNKDF
GSIFSTLLPG TMAKLEPPEG LEAWEGLEVK VAFGDIWKES LSELSGGQRS LIALSLILAL
LLYKPAPMYI LDEVDAALDL SHTQNIGNML RTHFSQSQFI VVSLKEGMFN NANVIFRTKF
VDGVSTVSRT LGSRGGSSRR AALANGNSSS GIQGAAKKRR GEHNAGKENS TQVM
//
