ID K0UN08_MYCVA Unreviewed; 303 AA.
AC K0UN08;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 24-JAN-2024, entry version 41.
DE RecName: Full=TIGR01777 family protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=MVAC_15023 {ECO:0000313|EMBL:EJZ08552.1};
OS Mycolicibacterium vaccae ATCC 25954.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=1194972 {ECO:0000313|EMBL:EJZ08552.1, ECO:0000313|Proteomes:UP000006072};
RN [1] {ECO:0000313|EMBL:EJZ08552.1, ECO:0000313|Proteomes:UP000006072}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25954 {ECO:0000313|EMBL:EJZ08552.1,
RC ECO:0000313|Proteomes:UP000006072};
RX PubMed=23105074; DOI=10.1128/JB.01462-12;
RA Ho Y.S., Adroub S.A., Abadi M., Al Alwan B., Alkhateeb R., Gao G.,
RA Ragab A., Ali S., van Soolingen D., Bitter W., Pain A., Abdallah A.M.;
RT "Complete Genome Sequence of Mycobacterium vaccae Type Strain ATCC 25954.";
RL J. Bacteriol. 194:6339-6340(2012).
CC -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC family. SDR39U1 subfamily. {ECO:0000256|ARBA:ARBA00009353}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJZ08552.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ALQA01000030; EJZ08552.1; -; Genomic_DNA.
DR RefSeq; WP_003933098.1; NZ_JH814698.1.
DR AlphaFoldDB; K0UN08; -.
DR eggNOG; COG1090; Bacteria.
DR HOGENOM; CLU_047373_0_2_11; -.
DR Proteomes; UP000006072; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013549; DUF1731.
DR InterPro; IPR001509; Epimerase_deHydtase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR010099; SDR39U1.
DR NCBIfam; TIGR01777; yfcH; 1.
DR PANTHER; PTHR11092:SF0; EPIMERASE FAMILY PROTEIN SDR39U1; 1.
DR PANTHER; PTHR11092; SUGAR NUCLEOTIDE EPIMERASE RELATED; 1.
DR Pfam; PF08338; DUF1731; 1.
DR Pfam; PF01370; Epimerase; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 7..216
FT /note="NAD-dependent epimerase/dehydratase"
FT /evidence="ECO:0000259|Pfam:PF01370"
FT DOMAIN 250..295
FT /note="DUF1731"
FT /evidence="ECO:0000259|Pfam:PF08338"
SQ SEQUENCE 303 AA; 31731 MW; E78510C1FD91BA98 CRC64;
MPSGSVVAVA GSSGLIGTAL VYALRATDRR VLRIVRRAPT NADEVFWNPD TGEFDPNTLR
GVDAVVNLCG VNVGQKRWSG AFKQSLRDSR IAPTEVLAGA AVEAGVPVLV NASAVGYYGD
TGSTPVDETA GPGDNFLARL SVDWEAATTV AARAGVRVVL ARTGLVMAPS GGMLSRLKPL
FSLGLGARLG NGRQYLSWVS LEDQVRALMF TLTHDELSGP VNVTGPAPVT NAEFTAALGR
SLNRPTPLVV PKFAVRVALG EFADEGVLGG QRAIPAALER AGFQFRHHTI GEALTFATSP
ERG
//
