ID K0VCP6_MYCVA Unreviewed; 422 AA.
AC K0VCP6;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 24-JAN-2024, entry version 43.
DE SubName: Full=Xaa-Pro aminopeptidase {ECO:0000313|EMBL:EJZ12643.1};
GN ORFNames=MVAC_01135 {ECO:0000313|EMBL:EJZ12643.1};
OS Mycolicibacterium vaccae ATCC 25954.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=1194972 {ECO:0000313|EMBL:EJZ12643.1, ECO:0000313|Proteomes:UP000006072};
RN [1] {ECO:0000313|EMBL:EJZ12643.1, ECO:0000313|Proteomes:UP000006072}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25954 {ECO:0000313|EMBL:EJZ12643.1,
RC ECO:0000313|Proteomes:UP000006072};
RX PubMed=23105074; DOI=10.1128/JB.01462-12;
RA Ho Y.S., Adroub S.A., Abadi M., Al Alwan B., Alkhateeb R., Gao G.,
RA Ragab A., Ali S., van Soolingen D., Bitter W., Pain A., Abdallah A.M.;
RT "Complete Genome Sequence of Mycobacterium vaccae Type Strain ATCC 25954.";
RL J. Bacteriol. 194:6339-6340(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EJZ12643.1}.
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DR EMBL; ALQA01000002; EJZ12643.1; -; Genomic_DNA.
DR RefSeq; WP_003928180.1; NZ_JH814683.1.
DR AlphaFoldDB; K0VCP6; -.
DR PATRIC; fig|1194972.3.peg.233; -.
DR eggNOG; COG0006; Bacteria.
DR HOGENOM; CLU_663608_0_0_11; -.
DR Proteomes; UP000006072; Unassembled WGS sequence.
DR GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR CDD; cd01066; APP_MetAP; 1.
DR Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 1.
DR InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR InterPro; IPR000587; Creatinase_N.
DR InterPro; IPR000994; Pept_M24.
DR PANTHER; PTHR46112; AMINOPEPTIDASE; 1.
DR PANTHER; PTHR46112:SF2; XAA-PRO AMINOPEPTIDASE P-RELATED; 1.
DR Pfam; PF01321; Creatinase_N; 1.
DR Pfam; PF00557; Peptidase_M24; 1.
DR SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR SUPFAM; SSF53092; Creatinase/prolidase N-terminal domain; 1.
PE 4: Predicted;
KW Aminopeptidase {ECO:0000313|EMBL:EJZ12643.1};
KW Hydrolase {ECO:0000313|EMBL:EJZ12643.1};
KW Protease {ECO:0000313|EMBL:EJZ12643.1}.
FT DOMAIN 38..145
FT /note="Creatinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01321"
FT DOMAIN 183..402
FT /note="Peptidase M24"
FT /evidence="ECO:0000259|Pfam:PF00557"
SQ SEQUENCE 422 AA; 45310 MW; 4CC1B50497F66044 CRC64;
MTASTDTGVT RIARTGYTWL DIPAEPDFAR MRREVGARLH AAMTEQGVDA LVLLGNGNVM
YATGISWPLA DAGLSHVERP VAVVLAGDEH PHLFLPFREG AAMESDLPDD HLHGPVYLEF
DEGVAEFARI LASLVPAGAK LATDELTGAM RRAGSALFPS PPVDAAPVVG AAKLVKTIDQ
IACVRRACQI TEQAVAEIQR SLVPGARQID LSAEFVRRAF ELGATTNMFD SIWQVMPASK
AEGAWTTTGD LALPLLTTER ELAQGDVLWT DVSIAYHGYC SDHGRTWIVG QDPTAAQQTQ
FDKWAQIVDA VLSVTKAGAT CGDLGRAATA AAGGEKPWLP HFYLGHGIGT SAAEMPMIGT
DLGQKWDDEF VFPDGMLLVF EPIVWADGTG GYRGEEIVVV TEGGWMPLTS YPYDPYEVSN
GR
//
