ID   K1A822_9STRE            Unreviewed;       231 AA.
AC   K1A822;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=Integral membrane protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=GMD6S_00920 {ECO:0000313|EMBL:EKA07273.1};
OS   Streptococcus sp. GMD6S.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=1169675 {ECO:0000313|EMBL:EKA07273.1, ECO:0000313|Proteomes:UP000004468};
RN   [1] {ECO:0000313|EMBL:EKA07273.1, ECO:0000313|Proteomes:UP000004468}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GMD6S {ECO:0000313|EMBL:EKA07273.1,
RC   ECO:0000313|Proteomes:UP000004468};
RX   PubMed=23493677; DOI=10.1101/gr.142208.112;
RA   Fitzsimons M.S., Novotny M., Lo C.C., Dichosa A.E., Yee-Greenbaum J.L.,
RA   Snook J.P., Gu W., Chertkov O., Davenport K.W., McMurry K., Reitenga K.G.,
RA   Daughton A.R., He J., Johnson S.L., Gleasner C.D., Wills P.L.,
RA   Parson-Quintana B., Chain P.S., Detter J.C., Lasken R.S., Han C.S.;
RT   "Nearly finished genomes produced using gel microdroplet culturing reveal
RT   substantial intraspecies genomic diversity within the human microbiome.";
RL   Genome Res. 23:878-888(2013).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EKA07273.1}.
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DR   EMBL; AJRH01000004; EKA07273.1; -; Genomic_DNA.
DR   RefSeq; WP_000138119.1; NZ_AJRH01000004.1.
DR   AlphaFoldDB; K1A822; -.
DR   PATRIC; fig|1169675.3.peg.183; -.
DR   Proteomes; UP000004468; Unassembled WGS sequence.
DR   GO; GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005384; F:manganese ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0030026; P:intracellular manganese ion homeostasis; IEA:InterPro.
DR   CDD; cd02432; Nodulin-21_like_1; 1.
DR   InterPro; IPR008217; Ccc1_fam.
DR   PANTHER; PTHR31851; FE(2+)/MN(2+) TRANSPORTER PCL1; 1.
DR   PANTHER; PTHR31851:SF52; PROTEIN CCC1; 1.
DR   Pfam; PF01988; VIT1; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        21..41
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        47..67
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        150..172
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        178..197
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        209..229
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   231 AA;  24689 MW;  FB55AC7993874B6F CRC64;
     MTEMKHEIDA NFAGRLNILR AGVLGANDGI ISIAGVVIGV ASATSNIWII FLSGLAAILA
     GAFSMAGGEY VSVSTQKDTE EAAVAREQLL LDKDIESAKQ SLYAAYLQNG ECETSAQLLT
     NKAFLKNPLK ALVEEKYGIE YEEFTNPWHA AISSFIAFVL GSLPPMLSIT VFPSDYRIPA
     TVFIVALSLL VTGYTSAKLG KAPTKTAMIR NLCIGLLTMG VTFLLGQLFS I
//