ID   K1LMC1_9LACT            Unreviewed;      1003 AA.
AC   K1LMC1;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   RecName: Full=Acyl-CoA synthetase FdrA {ECO:0008006|Google:ProtNLM};
GN   ORFNames=HMPREF9707_00953 {ECO:0000313|EMBL:EKB55766.1};
OS   Falseniella ignava CCUG 37419.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Aerococcaceae; Falseniella.
OX   NCBI_TaxID=883112 {ECO:0000313|EMBL:EKB55766.1, ECO:0000313|Proteomes:UP000005147};
RN   [1] {ECO:0000313|EMBL:EKB55766.1, ECO:0000313|Proteomes:UP000005147}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CCUG 37419 {ECO:0000313|EMBL:EKB55766.1,
RC   ECO:0000313|Proteomes:UP000005147};
RG   The Broad Institute Genome Sequencing Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Huys G., Walker B., Young S.K.,
RA   Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Goldberg J., Griggs A., Gujja S.,
RA   Hansen M., Howarth C., Imamovic A., Larimer J., McCowen C., Montmayeur A.,
RA   Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA   Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Facklamia ignava CCUG 37419.";
RL   Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EKB55766.1}.
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DR   EMBL; AGZE01000026; EKB55766.1; -; Genomic_DNA.
DR   AlphaFoldDB; K1LMC1; -.
DR   STRING; 883112.HMPREF9707_00953; -.
DR   PATRIC; fig|883112.3.peg.950; -.
DR   eggNOG; COG0074; Bacteria.
DR   HOGENOM; CLU_010999_0_1_9; -.
DR   Proteomes; UP000005147; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   Gene3D; 1.10.10.660; conserved protein of unknown function from Enterococcus faecalis V583; 1.
DR   Gene3D; 3.90.1710.10; Enterococcus faecalis V583 domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   Gene3D; 3.40.50.261; Succinyl-CoA synthetase domains; 2.
DR   Gene3D; 3.90.1700.10; v583 domain like; 1.
DR   InterPro; IPR003781; CoA-bd.
DR   InterPro; IPR009499; DUF1116.
DR   InterPro; IPR005811; SUCC_ACL_C.
DR   InterPro; IPR016102; Succinyl-CoA_synth-like.
DR   InterPro; IPR024033; Uncharacterised_dom_sf_YlbE.
DR   PANTHER; PTHR11117:SF2; SUCCINATE--COA LIGASE [ADP_GDP-FORMING] SUBUNIT ALPHA, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR11117; SUCCINYL-COA LIGASE SUBUNIT ALPHA; 1.
DR   Pfam; PF02629; CoA_binding; 1.
DR   Pfam; PF06545; DUF1116; 1.
DR   Pfam; PF00549; Ligase_CoA; 1.
DR   SUPFAM; SSF52210; Succinyl-CoA synthetase domains; 2.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005147}.
FT   DOMAIN          190..285
FT                   /note="CoA-binding"
FT                   /evidence="ECO:0000259|Pfam:PF02629"
FT   DOMAIN          341..494
FT                   /note="ATP-citrate synthase/succinyl-CoA ligase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00549"
FT   COILED          570..597
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   1003 AA;  107840 MW;  DB227B7B4B64661A CRC64;
     MLFTNIQKGN YQDSINLMLL SAELNNMPGV KQAQVMMATD ANKDIFAGAG LSTDELMAAG
     ANDMAIVVES DDESVMEVVL ERVESFLNDL SSKKSQTTQQ NVSHWQEALE ALPEANLALI
     SIPGQYAARE IEHALNQGLH VFSFSDNVAL EDEVRLKNKA HEAGLLLMGP DCGTGIISGI
     PLAFTNVVRP GNIGIVGASG TGIQEVTTII DRLGGGVVNE IGTGGRDLNE EVGARTMIDA
     ILALEAHPTT DVICVISKPP AKTIRDNVVE ILQSITKPVV AIFLGEKPME HAGNVAFAYT
     LEEAARMSVD LANGETLKVN YNEALDNHVE KALDGKTVKG LYSGGTLANE AAMLIADALD
     LGDIQNEQGY ILNANGFEVM DLGDDFYTQG KPHPMIDPSV RINKLKEVLQ DETTGIVLFD
     VVLGYGSHPD MVNALIPQIT EALDHAKANN RELHLIATVV GTDSDPQSYS QAIQDLKAAG
     VLVETTNARA VRLALELMGI DYKLPDRSFV DYQGEKVSLP TPSEQVMDLI TTQPRVINIG
     LEGFSESIQE FGGKVVQYDW RPRAGGNVKL IKVLDALDAH AEAIDEANEE IVQRMREAQP
     NLVDVKYAKE VIPELSHGKK IILHAGPPIK FENMTGPMQG SCIGAMLFEG WATDQADALR
     QLESGEVEFM PCHHVNAVGP MGGITTQNFP VFVVQNALDD TEGYCIMNEG IGNVLRFGAN
     NEEVITRLEW MRDVLGPVLG QALRAIDGGL NTSIMIARAI GMGDEFHQRN IAASLVFLKE
     VAPIITQLDI DEKDKQDTLQ FLADTDQFFL NIAMATGKVV VDYARKVQKG TVVTTMARNG
     ENFGIRIAAL GDQWFTAPVN TPNGLFFTGY SEEDANADIG DSAITETIGL GGSAMIAAPG
     VTRFIGAGGF EDAVRISNEQ AKIVVGQNPN WSIPTWDFRG ANLGIDIRKV IETGIEPIIN
     TGIAHKKAGV GQVGAGTVTA PVAAFEKALI AYAEHLGIDV DAL
//