ID   K1MY73_9LACO            Unreviewed;       405 AA.
AC   K1MY73;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   24-JAN-2024, entry version 36.
DE   SubName: Full=Exonuclease SbcCD, D subunit {ECO:0000313|EMBL:EKB74255.1};
GN   ORFNames=HMPREF9249_00544 {ECO:0000313|EMBL:EKB74255.1};
OS   Lactobacillus crispatus FB077-07.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Lactobacillus.
OX   NCBI_TaxID=883092 {ECO:0000313|EMBL:EKB74255.1, ECO:0000313|Proteomes:UP000004722};
RN   [1] {ECO:0000313|EMBL:EKB74255.1, ECO:0000313|Proteomes:UP000004722}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FB077-07 {ECO:0000313|EMBL:EKB74255.1,
RC   ECO:0000313|Proteomes:UP000004722};
RG   The Broad Institute Genome Sequencing Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Saerens B., Vaneechoutte M.,
RA   Walker B., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA   Abouelleil A., Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B.,
RA   Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A.,
RA   Larimer J., McCowen C., Montmayeur A., Murphy C., Neiman D., Pearson M.,
RA   Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J.,
RA   Nusbaum C., Birren B.;
RT   "The Genome Sequence of Lactobacillus crispatus FB077-07.";
RL   Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EKB74255.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AGZG01000026; EKB74255.1; -; Genomic_DNA.
DR   RefSeq; WP_005728278.1; NZ_JH932272.1.
DR   AlphaFoldDB; K1MY73; -.
DR   PATRIC; fig|883092.3.peg.545; -.
DR   HOGENOM; CLU_026621_4_1_9; -.
DR   OrthoDB; 9773856at2; -.
DR   Proteomes; UP000004722; Unassembled WGS sequence.
DR   GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR   CDD; cd00840; MPP_Mre11_N; 1.
DR   Gene3D; 3.60.21.10; -; 1.
DR   InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR   InterPro; IPR029052; Metallo-depent_PP-like.
DR   InterPro; IPR041796; Mre11_N.
DR   InterPro; IPR014576; Pesterase_YhaO.
DR   PANTHER; PTHR30337; COMPONENT OF ATP-DEPENDENT DSDNA EXONUCLEASE; 1.
DR   PANTHER; PTHR30337:SF7; PHOSPHOESTERASE; 1.
DR   Pfam; PF00149; Metallophos; 1.
DR   PIRSF; PIRSF033091; Pesterase_YhaO; 1.
DR   SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
PE   4: Predicted;
KW   Exonuclease {ECO:0000313|EMBL:EKB74255.1};
KW   Hydrolase {ECO:0000313|EMBL:EKB74255.1};
KW   Nuclease {ECO:0000313|EMBL:EKB74255.1}.
FT   DOMAIN          1..200
FT                   /note="Calcineurin-like phosphoesterase"
FT                   /evidence="ECO:0000259|Pfam:PF00149"
SQ   SEQUENCE   405 AA;  45407 MW;  52AAEE5888D7DA24 CRC64;
     MKFIHFADAH LDSPFRGLSF LPSEEFNHIY QAADQSLTKI VDLALQENVD LVLIAGDTFD
     SNTPSPRAQL FFAKQIKRLT DQKIQVVMIF GNHDHMKQED LLVSPSPYFK LLGNNETVEQ
     ATFTTDAGFN YDVIGFSYLN NHITEDKIPE FPAKGKNYTF GLMHAQEKSA TASQNVYAPF
     TVDELQNLNY DYFALGHIHA RNNLSSTPWI VYPGNIQGRH INEMGAKGCY LGEIDENSGK
     TTIDFKETGP ILWQGTKINL EGAISKADLQ AKIIAKLESG QKTYFSLTIA GAQYLSAEER
     DLVQDLDFWQ TISQSLPFAS QLVDVRFVVN TSLKLNDNDQ QAFQAAKEEL FAPAEFKQIV
     SDWQKKDPEA AKLAADPDFI AAVKNLTEVK LMSKLKGIKD ETETN
//