ID K1PU78_CRAGI Unreviewed; 774 AA.
AC K1PU78;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 24-JAN-2024, entry version 44.
DE SubName: Full=Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 {ECO:0000313|EMBL:EKC27857.1};
GN ORFNames=CGI_10022641 {ECO:0000313|EMBL:EKC27857.1};
OS Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC27857.1};
RN [1] {ECO:0000313|EMBL:EKC27857.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC27857.1};
RX PubMed=22992520; DOI=10.1038/nature11413;
RA Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT "The oyster genome reveals stress adaptation and complexity of shell
RT formation.";
RL Nature 490:49-54(2012).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; JH816091; EKC27857.1; -; Genomic_DNA.
DR AlphaFoldDB; K1PU78; -.
DR HOGENOM; CLU_361404_0_0_1; -.
DR InParanoid; K1PU78; -.
DR OMA; EHICHTH; -.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00053; EGF; 1.
DR CDD; cd00054; EGF_CA; 2.
DR Gene3D; 2.10.25.10; Laminin; 4.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR013032; EGF-like_CS.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR035234; IgGFc-bd_N.
DR PANTHER; PTHR46534; IGGFC_BINDING DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46534:SF1; IGGFC_BINDING DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00008; EGF; 2.
DR Pfam; PF12661; hEGF; 1.
DR Pfam; PF17517; IgGFc_binding; 1.
DR SMART; SM00181; EGF; 4.
DR SMART; SM00179; EGF_CA; 4.
DR SUPFAM; SSF57196; EGF/Laminin; 4.
DR PROSITE; PS00010; ASX_HYDROXYL; 2.
DR PROSITE; PS00022; EGF_1; 3.
DR PROSITE; PS01186; EGF_2; 4.
DR PROSITE; PS50026; EGF_3; 4.
DR PROSITE; PS01187; EGF_CA; 2.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076}.
FT DOMAIN 493..530
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 532..568
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 570..605
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 607..642
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 558..567
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 574..584
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 595..604
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 611..621
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 632..641
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 774 AA; 84219 MW; 8829274E563CA554 CRC64;
MDGATALTLG IFLLSVIPSY VHGLMDNRGT KFVLGFMENF QATLFSELFI TTSKSLPVSV
NITSPRWHTS GMHLSLTVVS GTVEQVNISS SLRMTGSSLS SKGLLIEASD EIVVYGFNKE
PFSNDAFLGI PCDVIGSEYY VTAYFPSFFS SEILVVGVSN ATSLQIKLSE TLQSLVYFQG
GNFSKGQWIN FTVDAYDTLQ LQSAGDVTGT FIKSDKPVSV FSGNVLTAVG NGTADHLAEQ
HISVDKWGKS YATVPIPERI VGDYFRLIAS EHHTKVVVQG LDGSFQHTET LTLSKPGDWV
QRHFSSSLYA FITSDKPIYV VQYSLSQVNR NMADPSMIII PPMELYAAHY VFTTPKSATG
SYDSYFMFVV KKVDLDGLRI NGLPLNATEI REFPGGEYVG GHVPLSEGTY DIRHISPICV
FGGVLYGRGW FETYGFATGM RLTSINEPCI QNSQSPGDGL DNDCDRKIDE EIENNQDDDG
DGLIDEDCAK PYQDRPCFAT PCYNGGTCVE SGANYTCTCI HGYDPASDCR STIDFCLRNP
CPHTKVCLPH LGGFTCVCTA GFTGTDCTSD IDECASSPCI HGNCTDNVNG YRCLCDAGYA
GLHCESNVDE CASSPCIHGN CTDDVNSFHC SCDVGFSGIT CTSTVSSSEC SSSNCNVVRC
SIFNLQLGTA CYYAWVSCLL SALVLATLSF CVIFIYGIKK RQRLSKEQRS PFPFEDTTLG
ESKKRFDFNL RDMTTFCVVT LICDSGSFAI APWVASSSTK NVDAHSKTKA PVVD
//
