ID   K1Q630_CRAGI            Unreviewed;      1177 AA.
AC   K1Q630;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   27-MAR-2024, entry version 58.
DE   RecName: Full=Structural maintenance of chromosomes protein {ECO:0000256|PIRNR:PIRNR005719};
GN   ORFNames=CGI_10012094 {ECO:0000313|EMBL:EKC29388.1};
OS   Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC   Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX   NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC29388.1};
RN   [1] {ECO:0000313|EMBL:EKC29388.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC29388.1};
RX   PubMed=22992520; DOI=10.1038/nature11413;
RA   Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA   Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA   Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA   Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA   Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA   Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA   Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA   Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA   Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA   Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA   Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT   "The oyster genome reveals stress adaptation and complexity of shell
RT   formation.";
RL   Nature 490:49-54(2012).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|PIRNR:PIRNR005719}.
CC   -!- SIMILARITY: Belongs to the SMC family. SMC1 subfamily.
CC       {ECO:0000256|ARBA:ARBA00005597}.
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DR   EMBL; JH817564; EKC29388.1; -; Genomic_DNA.
DR   AlphaFoldDB; K1Q630; -.
DR   HOGENOM; CLU_001042_0_2_1; -.
DR   InParanoid; K1Q630; -.
DR   OMA; SYIRDHT; -.
DR   GO; GO:0008278; C:cohesin complex; IEA:InterPro.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0007062; P:sister chromatid cohesion; IEA:InterPro.
DR   CDD; cd03275; ABC_SMC1_euk; 2.
DR   Gene3D; 3.30.70.1620; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR003395; RecF/RecN/SMC_N.
DR   InterPro; IPR024704; SMC.
DR   InterPro; IPR028468; Smc1_ABC.
DR   InterPro; IPR010935; SMC_hinge.
DR   InterPro; IPR036277; SMC_hinge_sf.
DR   PANTHER; PTHR18937:SF12; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN; 1.
DR   PANTHER; PTHR18937; STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER; 1.
DR   Pfam; PF06470; SMC_hinge; 1.
DR   Pfam; PF02463; SMC_N; 1.
DR   PIRSF; PIRSF005719; SMC; 2.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF75553; Smc hinge domain; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR005719}.
FT   DOMAIN          4..1147
FT                   /note="RecF/RecN/SMC N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02463"
FT   DOMAIN          519..560
FT                   /note="SMC hinge"
FT                   /evidence="ECO:0000259|Pfam:PF06470"
SQ   SEQUENCE   1177 AA;  136750 MW;  BFD38DBDC3F9AE02 CRC64;
     MPGYLRYIEV DNFKSYVGQQ RIGPFDRFTA IIGPNGSGKS NLMDAISFVL GEKTSNLRVK
     RMSDLIHGAP VGKPAANKAS VNAVYVNSVN GEETHFTRVI HGSSSDHKVN GKIVSAQDYA
     NELEKIGVLV KSKNFLVFQG TVESIAMKNA KERMVMFEEI SRSGELKEEY DKAKAEMNKA
     EEDTQFNYHK KKGIAAERKE AKMEKDEAER YQKLKEQIAE KQLELQLFKL YHNEAEIDEL
     ADELQKKTNM LEKENRRRER IEEEIKEKKK EQGKVARELT KVEQSIKESE VELNKKRPLY
     IKAKEKTSHM IKKLDAAKKS LKQAKKSHEN HETEIQEMEK ELEEVEKKQQ EFENQIEEES
     QSQGRDLDLE ENQLQEYHRL KEEAGKNAAR YMQEMDSITR EQKSDQDRFD NENRKKNELI
     AKIKQKENEM EENRKRVEKL DDYVRTSETA VADLKRSEME LSEQVETANV RVNEINDELA
     SIMEQLGEAK VDKHESSRAI KKKELLENLR RLFPGVIREP KNVKLVVDVI RYDPPSIKKA
     LLFACGNALV CDTVEDARHV AFGTHDRHKS VALDGTLFQK SGVISGGASD LRAKARRWDE
     KQLGQLKNKK EKLSEELKES VKQRRKESEL STMRSQIKGY ETRLKYSITD RDNLLNKQLT
     QNEKDLSMYN QMLEQYDPRM QEIEKRMMER GQQMKILKEK MNRVEDEVFR DFCLMLGVSN
     IRQFEERELR SQQERAKKRL EFENQKFRLQ NQIEFERSRD TIANVRKWEA AFKNDEKELE
     KVKNDEARHM KIIEEAMDQQ EKAKRQRITL KSQVDDFETE ISEIKKRLNN QQKEMANAQK
     QITMVETKLE QKRADRHSLL KACKMDDIRL PMRMGTMDDI SREDEPSSQP DSQSTADTPL
     DSMSSQGQKA IYAKEAQIQI DYSSLDEDVK ELDTPEDVKK QTEIMTKALS DMNSNLNRIN
     APNMKAMEKL DGVRERFQET SEEFENARKR AKRAKQVYEK VRKERYDRFM HCFEHVSTRI
     DEIYKALARN QSAQAFLGPE NPEEPYLDGV NYNCVAPGKR FRPMDNLSGG EKTVAALALL
     FAIHSYQPAP FFVLDEIDAA LDNTNIGKVA SYICEQSRAS FQCIVISLKE EFYNKSDALI
     GIYPEQGDCV ISNVLTLDLK QYPDSHQEDD GFQGIPR
//