ID K1Q9X2_CRAGI Unreviewed; 1538 AA.
AC K1Q9X2;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Multiple epidermal growth factor-like domains 6 {ECO:0000313|EMBL:EKC18251.1};
GN ORFNames=CGI_10014124 {ECO:0000313|EMBL:EKC18251.1};
OS Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC18251.1};
RN [1] {ECO:0000313|EMBL:EKC18251.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC18251.1};
RX PubMed=22992520; DOI=10.1038/nature11413;
RA Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT "The oyster genome reveals stress adaptation and complexity of shell
RT formation.";
RL Nature 490:49-54(2012).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; JH818655; EKC18251.1; -; Genomic_DNA.
DR HOGENOM; CLU_004998_0_0_1; -.
DR InParanoid; K1Q9X2; -.
DR OMA; HLCEHCP; -.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR Gene3D; 2.10.25.10; Laminin; 10.
DR Gene3D; 2.170.300.10; Tie2 ligand-binding domain superfamily; 8.
DR InterPro; IPR026823; cEGF.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR002049; LE_dom.
DR InterPro; IPR042635; MEGF10/SREC1/2-like.
DR PANTHER; PTHR24043:SF8; EGF-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24043; SCAVENGER RECEPTOR CLASS F; 1.
DR Pfam; PF12662; cEGF; 2.
DR Pfam; PF07645; EGF_CA; 1.
DR Pfam; PF14670; FXa_inhibition; 5.
DR Pfam; PF00053; Laminin_EGF; 7.
DR PRINTS; PR00011; EGFLAMININ.
DR PRINTS; PR00907; THRMBOMODULN.
DR SMART; SM00181; EGF; 33.
DR SMART; SM00179; EGF_CA; 9.
DR SMART; SM00180; EGF_Lam; 23.
DR SUPFAM; SSF57184; Growth factor receptor domain; 3.
DR PROSITE; PS00010; ASX_HYDROXYL; 3.
DR PROSITE; PS00022; EGF_1; 18.
DR PROSITE; PS01186; EGF_2; 7.
DR PROSITE; PS50026; EGF_3; 9.
DR PROSITE; PS01187; EGF_CA; 2.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076}.
FT DOMAIN 65..100
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 102..142
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 143..183
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 531..566
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 965..1000
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1094..1129
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1228..1258
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1266..1301
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 1400..1430
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 90..99
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 556..565
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 990..999
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1119..1128
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1248..1257
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1291..1300
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 1420..1429
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 1538 AA; 166963 MW; 5AD7D1EFC319F411 CRC64;
MDLHFCELFL LVFVIGITPS KGTYNLRAGM TQYFTTYKQD YRRFVVTKYQ CCHGWQQLHS
QAGCMYRQCS QTACLNGGRC VDGNTQRCVC PSGFQGSRCQ YDVNECTKGI SGCDQDCLNT
MGSFQCKCRQ GFRLGRDGRT CEDINECDNG KGGCQHECHN THGGYQCLCP VGYRLRADGR
SCEVESACRV NNGDCEQVCL EGSVRGHYRC GCREGYQLKS DSRTCELTDP CRNRNGDCEH
TCINNNGNRV CECYRGYKLS ADQRHCEDIN ECLNNNGGCS QECANTQGSF ECRCHPGFQL
GINRKSCYRV ELEPVDSCAI NNGGCAHSCR HEDGGAVCSC RKGYILQIDR KSCLDADECG
LEQACCAHHC SNNPGGYTCS CRSGFALNRN DGCSCDDVNE CLTDNGGCEQ ECVNKEGSFT
CVCKPGYRLA PNNRGCILID TGPHRGDIPS PLQYKASIRP LPLVESLKLQ DELIDADIKY
ECVRGSFGPD CEWTCDSCQN GASCNHDNPG CLCAPGWQGF LCNQTCPLGF YGSGCSKNCT
CQNGGTCDHV TGRCTCPPGV RGESCEDGCP AGFFGKNCDK ICSTPCHSGH CNREFGYCQC
PPGFVGPYCN ARCPSFNWGS NCVNTCRCNR TTTDYCNPEN GKCSCKKGFH GDQCEFRCSQ
GHYGKNCEEK CHCNNNQSCD PENGRCYLRC AQGRMGDSCD QICPRGSFGF NCEQKCNCHN
SECSPETGRC ICRAGMRGRH CNKPCRNGTW GVNCMYECTC KKGECDKVTG ECICPDGWYG
LECQNACPPN RYGFQCLLQC KCENNAMCNP TDGSCKCKEG FRGTFCDQVC PPGTYGPDCI
YRCACKNGAE CDHITGECIC GPGWKGVGCD EMCEPGTYGA GCKEKCRCAN GASCDHIGGG
CTCDEGWQGK HCDKPCPQGF FGMDCRGVCN CGNNGAECNH VTGECKCSAG WTGMDCSKTC
PLGTFGEGCQ HQCHCGNGGT CDPVSGACVC AAGWRGNHCE EECPRGFYGI NCLYHCFCRN
DAPCNSITGE CNCTSGFTGT ACEKSCYEGF YGPNCVHQCK CLHGESCDKE TGKCKCLPGY
HGEFCDKECP QGFYGEDCDE SCGCQNGASC HHVTGTCTCT AGWRGRQCHR PCMRGFYGKD
CMEVCRCEDD KPCDHVSGIC ECPPGFTGSS CQENCPEGRF GEGCNKTCDC DQNSVCDPVT
GRCSCRPGYS GKNCSRGCEE GMFGVSCENK CNCENGATCD PTTGTCMCPL GYIGPTCSEP
CPRGYTGQGC RHVCKCRNEA TCDPENGRCL CPPGYHGDRC QFKCDENSFG KDCSGNCNCS
ENGRCDPVTG QCHCDLGWMG DRCDQLCPSG KFGPACVHSC VCQNNGSCDP VSGCCSCLPG
FYGQSCEFSC PEGTHGLYCR ETCSCKNGAK CNPINGQCRC KPGYHGDNCQ HMCSRGFYGS
KCREECQCGS SHCDHVTGEC FCPVGLKGAN CTNMCKQGKY GPNCEFFCDC DNQGFCDPES
GACVCRGGFT GSRCQYISAS SSTRRGDIPW NVHYFGRR
//
