ID K1QBH4_CRAGI Unreviewed; 788 AA.
AC K1QBH4;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=ATP-dependent RNA helicase DDX42 {ECO:0000313|EMBL:EKC34097.1};
GN ORFNames=CGI_10018969 {ECO:0000313|EMBL:EKC34097.1};
OS Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC34097.1};
RN [1] {ECO:0000313|EMBL:EKC34097.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC34097.1};
RX PubMed=22992520; DOI=10.1038/nature11413;
RA Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT "The oyster genome reveals stress adaptation and complexity of shell
RT formation.";
RL Nature 490:49-54(2012).
CC -!- SIMILARITY: Belongs to the DEAD box helicase family.
CC {ECO:0000256|RuleBase:RU000492}.
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DR EMBL; JH818639; EKC34097.1; -; Genomic_DNA.
DR AlphaFoldDB; K1QBH4; -.
DR HOGENOM; CLU_003041_9_0_1; -.
DR InParanoid; K1QBH4; -.
DR OMA; DHTWEQT; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR CDD; cd17952; DEADc_DDX42; 1.
DR CDD; cd18787; SF2_C_DEAD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000629; RNA-helicase_DEAD-box_CS.
DR InterPro; IPR014014; RNA_helicase_DEAD_Q_motif.
DR PANTHER; PTHR47959:SF13; ATP-DEPENDENT RNA HELICASE RHLE; 1.
DR PANTHER; PTHR47959; ATP-DEPENDENT RNA HELICASE RHLE-RELATED; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00039; DEAD_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS51195; Q_MOTIF; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU000492};
KW Helicase {ECO:0000256|RuleBase:RU000492, ECO:0000313|EMBL:EKC34097.1};
KW Hydrolase {ECO:0000256|RuleBase:RU000492};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU000492}.
FT DOMAIN 297..325
FT /note="DEAD-box RNA helicase Q"
FT /evidence="ECO:0000259|PROSITE:PS51195"
FT DOMAIN 328..503
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 532..676
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 788 AA; 87514 MW; DEC4908CBCFB916D CRC64;
MLEFLCFRHV DSVRARESLD SLQVVVQGVS GIAFSWEILG ICQQIAGNIQ AALNYFTMSS
RGSENKTKGF GFSGFTISKK EDSTASQSGL GGMPSGGSKF MPGRSFGYHT NIGKKRARNE
DEYFEEEDEE DNMAYQPAPG SPGEEKNEES EEEDPLDAFM ADIETEVKCQ QPKESTIKEK
PKEKKKDKGV RDDIDQEDDQ ESFFRYMEEN PLAGVVFDDD ETVIEYDAEG NPIIPEKNKI
IDPLPPVDHS DIDYGPFVKN FYVEHEDIAK LQPNEVDELR KKLGIRVSGF NPPKPVSSFA
HFGFDENLMS AIRKSEFSQP TPIQAQGIPL ALNGRDIIGI AKTGSGKTAA FLWPLLVHIM
DQRELEEGEG PVGLILAPTR ELSQQIYHEA KKFGKVYNIN VVCAYGGGSM WEQTKACQEG
AEIIVATPGR LIDLVKKRAT NLERVTYLVF DEADRMFDMG FEPQVRSIAN HVRPDRQTML
FSATFRKKVE KLARDILLDP VRVVQGEAGE ANEDITQVVE VLPLGPAKWT WLIKRLVEFT
TIGSVLIFVT RKANAEELAT NLRARDFKIG LLHGDMSQME RNDVITTFKK KEIPILVATD
VAARGLDIPS IKTVVNYDVA RDIDTHTHRI GRTGRAGEKG FAYTLVTEKD KDFAGHLVRN
LETAGQHVPH ALLELAEKNP WFKKIRGKQG GKGKKLNLGG KGLGFKERPG LGAESSTKVQ
DSSSLSSYRG IGTSAGPQSD RLSAMKAAFT AQFKSNFVAA ESTSMPKVEP GVYNPINSSS
RKKKSRWN
//
