ID K1QXB6_CRAGI Unreviewed; 792 AA.
AC K1QXB6;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Otopetrin-2 {ECO:0000313|EMBL:EKC33560.1};
GN ORFNames=CGI_10014450 {ECO:0000313|EMBL:EKC33560.1};
OS Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC33560.1};
RN [1] {ECO:0000313|EMBL:EKC33560.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC33560.1};
RX PubMed=22992520; DOI=10.1038/nature11413;
RA Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT "The oyster genome reveals stress adaptation and complexity of shell
RT formation.";
RL Nature 490:49-54(2012).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the otopetrin family.
CC {ECO:0000256|ARBA:ARBA00006513}.
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DR EMBL; JH823243; EKC33560.1; -; Genomic_DNA.
DR RefSeq; XP_011423436.1; XM_011425134.2.
DR AlphaFoldDB; K1QXB6; -.
DR GeneID; 105325518; -.
DR KEGG; crg:105325518; -.
DR HOGENOM; CLU_011508_0_1_1; -.
DR InParanoid; K1QXB6; -.
DR OMA; WTWFRFV; -.
DR OrthoDB; 2955117at2759; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015252; F:proton channel activity; IEA:InterPro.
DR InterPro; IPR004878; Otopetrin.
DR PANTHER; PTHR21522:SF32; OTOPETRIN-LIKE A, ISOFORM C; 1.
DR PANTHER; PTHR21522; PROTON CHANNEL OTOP; 1.
DR Pfam; PF03189; Otopetrin; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
SQ SEQUENCE 792 AA; 89627 MW; 93566B0439ABE0AB CRC64;
MSMLDTQETE PRIQPKHVEN SSENGVSGSD PNSSDAESDP KTQTSQNALQ SGIKPIPKAR
SSSEIQPSDT CRKQEFGRRH SAFGNEKQIP SELSRQGEEK ITNISHDSEN LLSKQTDKKY
ATTSKMRRKS GSDKQENISE SGDTENGFRI SSDRRHFYTV NDSSEEILAL VDLGANRVHR
DSTGRYHDYI TNVSERTYDE NEDDIMLCEE ETEAERKAIA EKLRDNVSVV ASMMYGILMS
VLAAVVPITE TFASQSPSQM FEIFYIFMYL VSFIFVMYTN LIILKRKSRL MKFLLAIIGR
VRGLLMNKSD KGVVNGRAGE EPSAISRRSF NTDTTHLMYS GSFPLRIGAV VFGVASMVHS
GLNFAYFFQV RDGNAQCHHP VQAIKPFMHL TFTFTQLYFI FLHSKLVFTH QKCIARLGLM
HLCCTNLAVW FRCIILETLD VLSGYHHRGS GKTGPENVTE IPLIKSSAAS RKLLGIPESH
LILISLPMNN SNVFPELSCF WSDIFGKFVQ TAGPYLYPCK IQYSLICAAI VYAMWRNVGR
KPSSRDQNDS VNNSRRLDCS SSFRGLFAGI LVAVGTVITM VAFYVLVTLH PMSSTAIILI
HVSETTMFLL MTASIILVAD RMKNMKFKHV SWKFSVELHL LFLSFAGVFA FAVFGVIAAA
FETHKPKGVL NILTNLFMIL QSTMQVLFIV AGTKLISANE LQEQRKRGRE YVMFLILCNF
ALWLMNTFET QQPEHNPVQM DFYGPLAWSV LTHITVPLSI YFRFHSSVCL INIWRFAWRY
RSPRETERES SC
//
