ID K1QYH9_CRAGI Unreviewed; 636 AA.
AC K1QYH9;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=RING-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012483};
DE EC=2.3.2.27 {ECO:0000256|ARBA:ARBA00012483};
GN ORFNames=CGI_10028226 {ECO:0000313|EMBL:EKC42037.1};
OS Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC42037.1};
RN [1] {ECO:0000313|EMBL:EKC42037.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC42037.1};
RX PubMed=22992520; DOI=10.1038/nature11413;
RA Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT "The oyster genome reveals stress adaptation and complexity of shell
RT formation.";
RL Nature 490:49-54(2012).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC EC=2.3.2.27; Evidence={ECO:0000256|ARBA:ARBA00000900};
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DR EMBL; JH818444; EKC42037.1; -; Genomic_DNA.
DR AlphaFoldDB; K1QYH9; -.
DR HOGENOM; CLU_430388_0_0_1; -.
DR InParanoid; K1QYH9; -.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:InterPro.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR045194; MGRN1/RNF157-like.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR22996; MAHOGUNIN; 1.
DR PANTHER; PTHR22996:SF0; RING-TYPE E3 UBIQUITIN TRANSFERASE; 1.
DR Pfam; PF13920; zf-C3HC4_3; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022771};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
SQ SEQUENCE 636 AA; 70745 MW; D94041529F26E241 CRC64;
MGGITSRDAG EEEIDTASTN AYRYPPKIGN YFGSYFYMGG ERFEMSQPEA YLFGENSDLN
FLGSKPMPFP YQGSTSGSEP TKPLKSLVNI RKDSLKFVKV EDSEQKPEGD ESDESDPSST
KYNIEFTFDS DSKCAITIYY FATEDVNNGQ ITFQTKEACL NSETFHYKRG ANQLFSQSTH
VLDPSKFSDE EWQYDPVKET IPVVISCVVE DDDHPCHSHM TYAVVEKSSV DGGYMIKALK
QKQFVDGLLY LLQEIYGIEN KQTDRSKLED PDDEVEDSGA ECVICMSDMR DTLILPCRHL
CLCSNCAESL RYQASSCPIC RSPFRALLQI RAMRKKQPLS VQTGETQGEE NPVSQEGVPT
GYEAVSLIEA VNGPCNQFFS VDGGLQLPVR NIALDVDSSY REKKQKLSKR HMISVKTEDP
VVSPNVKPDD KKVLDEEEEE RKNEEPLEVP NVKVPFFRYA VGKEVSDKLN ASKIVSVGED
YNTDSLDSKG MRTATLRVYE SEADSDYDLK PMGSNQGHTS TENLADDERE DSSEAEPEPE
PDYDDDLISE AVKSESALNV SEKQGSADYK DKGQTYVKGL SRSMNDVNRD NSGYHPLCLQ
SNASLPETST SGNEASSFGS TDSSGKLLID TAESTD
//
