ID   K1R0F5_CRAGI            Unreviewed;       837 AA.
AC   K1R0F5;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   27-MAR-2024, entry version 42.
DE   SubName: Full=Prominin-1-A {ECO:0000313|EMBL:EKC36929.1};
GN   ORFNames=CGI_10023076 {ECO:0000313|EMBL:EKC36929.1};
OS   Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC   Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX   NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC36929.1};
RN   [1] {ECO:0000313|EMBL:EKC36929.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC36929.1};
RX   PubMed=22992520; DOI=10.1038/nature11413;
RA   Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA   Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA   Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA   Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA   Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA   Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA   Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA   Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA   Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA   Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA   Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT   "The oyster genome reveals stress adaptation and complexity of shell
RT   formation.";
RL   Nature 490:49-54(2012).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the prominin family.
CC       {ECO:0000256|ARBA:ARBA00006058}.
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DR   EMBL; JH816585; EKC36929.1; -; Genomic_DNA.
DR   AlphaFoldDB; K1R0F5; -.
DR   HOGENOM; CLU_008293_0_0_1; -.
DR   InParanoid; K1R0F5; -.
DR   OMA; DWANFTI; -.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR008795; Prominin.
DR   PANTHER; PTHR22730; PROMININ PROM PROTEIN; 1.
DR   PANTHER; PTHR22730:SF1; PROMININ-LIKE PROTEIN; 1.
DR   Pfam; PF05478; Prominin; 3.
PE   3: Inferred from homology;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
SQ   SEQUENCE   837 AA;  91276 MW;  41DFC42C347918D3 CRC64;
     MGRVVRHWTG IVILLAWINL GYCDDPVLTP ATLTDSGGNT ANANSSIKWA PLPSFDSYKA
     GDIEYDSSGL APLNNFAKSF INGAVFPLGV PWDLMEKAID GTLMTDITAN YMNFGGYGAC
     IVIGFLFIFI FPLIGLCFCC CRCCCSNCGG KMMQHNEDVK ADCKRRTFAI ILFVLIAFTG
     AGMICVYLSN DQMSTALNNF DDVVVSNMDD LTTYASNVVK ETKYIVNTNF NFTTSVITRD
     LDRVTQIAAA LTTLNTTLGD VKVKAEILSS NLTTLKTDID TAITSAGCPG APNCPDTSGV
     VMGFDTNDFP DISGPLSSIS SVENQNLSAI IIQASSEIEN IPERVTNETR TTVSDLKTMV
     SNFSGEIDPL IEQVENIQDS ISTNGTIADI KKQVKDMVDV GSTYDKYRWY GGVGLTSIVL
     LVVLLQILGL GFGTCSQNSN TRPTERGCVG TSAGKMLMAL WTRYTSSSMV LRTAPYLVKC
     SLTTLALTLG SANFCSSHEA NDTLVSGSLH RDCQGGAAAF KALKLNNLFD VSTLTNFTKS
     EVDKINIDLS TVKIMTPSLL DQLNEMKNAI NVNFTKFREE LGKSTTGQNM SALADQLDTL
     AGSCSPGCNA ATQTSLRDLA TRTRSIESNE LANLTTALTQ LGPDLNTLES TVNGTDTDVD
     NCINNFNISE IFVQNNGSDV VKNEAKKFAD RIIGIVTSFA DDALYALDNE IGKCTPIWNL
     YNTLFVISLC QYTVDSLNGF WFSLGWCIFF FIPSIIFSTK LAKHYRRMSQ LDNDYEDDKD
     ELQLPEVSSD KYHILHNKVH PEDKEWNGSK SPFGSNKVGH YDPSSAQSNP PPYNTDW
//