ID   K1R6P8_CRAGI            Unreviewed;       239 AA.
AC   K1R6P8;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   13-SEP-2023, entry version 40.
DE   SubName: Full=Toll-like receptor 2 type-2 {ECO:0000313|EMBL:EKC29626.1};
GN   ORFNames=CGI_10027415 {ECO:0000313|EMBL:EKC29626.1};
OS   Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC   Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX   NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC29626.1};
RN   [1] {ECO:0000313|EMBL:EKC29626.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC29626.1};
RX   PubMed=22992520; DOI=10.1038/nature11413;
RA   Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA   Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA   Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA   Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA   Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA   Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA   Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA   Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA   Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA   Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA   Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT   "The oyster genome reveals stress adaptation and complexity of shell
RT   formation.";
RL   Nature 490:49-54(2012).
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DR   EMBL; JH819194; EKC29626.1; -; Genomic_DNA.
DR   AlphaFoldDB; K1R6P8; -.
DR   HOGENOM; CLU_1162121_0_0_1; -.
DR   InParanoid; K1R6P8; -.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; IEA:InterPro.
DR   Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR   InterPro; IPR000157; TIR_dom.
DR   InterPro; IPR017241; Toll-like_receptor.
DR   InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR   PANTHER; PTHR24365:SF541; MSTPROX-RELATED; 1.
DR   PANTHER; PTHR24365; TOLL-LIKE RECEPTOR; 1.
DR   Pfam; PF13676; TIR_2; 1.
DR   SMART; SM00255; TIR; 1.
DR   SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 2.
DR   PROSITE; PS50104; TIR; 1.
PE   4: Predicted;
KW   Receptor {ECO:0000313|EMBL:EKC29626.1}.
SQ   SEQUENCE   239 AA;  28399 MW;  5434A27A22EAA9E4 CRC64;
     MVVYKKRWAL IYRWYLFRLR QKGYTPIGGC DEGYHFDAFL SFADEDRPFV ERVVTELEEN
     SELHFKTICL LFILSVIALV VYKKRWTLIY RWYMFRLKRK RYTPIGGCAG GYQFDAFLSF
     ADEDRPFVDR VIDELEGNPE VKLNVCVHFR DFIPGKSISG NIVTSIHSCK KTIVFMSRAY
     LKSDWCKYEL RMAITEESHM NREVVIMTVL EDIPHKELSL DVLQYYKKNS YINKPNTED
//