ID K1R852_CRAGI Unreviewed; 219 AA.
AC K1R852;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=Ras-related protein Rab-3 {ECO:0000256|RuleBase:RU367096};
GN ORFNames=CGI_10021960 {ECO:0000313|EMBL:EKC30136.1};
OS Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC30136.1};
RN [1] {ECO:0000313|EMBL:EKC30136.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC30136.1};
RX PubMed=22992520; DOI=10.1038/nature11413;
RA Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT "The oyster genome reveals stress adaptation and complexity of shell
RT formation.";
RL Nature 490:49-54(2012).
CC -!- FUNCTION: Protein transport. Probably involved in vesicular traffic.
CC {ECO:0000256|RuleBase:RU367096}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU367096};
CC Lipid-anchor {ECO:0000256|RuleBase:RU367096}; Cytoplasmic side
CC {ECO:0000256|RuleBase:RU367096}.
CC -!- SIMILARITY: Belongs to the small GTPase superfamily. Rab family.
CC {ECO:0000256|ARBA:ARBA00006270, ECO:0000256|RuleBase:RU367096}.
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DR EMBL; JH818702; EKC30136.1; -; Genomic_DNA.
DR RefSeq; XP_011413953.1; XM_011415651.2.
DR RefSeq; XP_011413955.1; XM_011415653.2.
DR AlphaFoldDB; K1R852; -.
DR GeneID; 105318488; -.
DR HOGENOM; CLU_041217_10_1_1; -.
DR InParanoid; K1R852; -.
DR OMA; AQQQCNC; -.
DR OrthoDB; 8685at2759; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003924; F:GTPase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006886; P:intracellular protein transport; IEA:UniProtKB-UniRule.
DR CDD; cd01865; Rab3; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR037872; Rab3.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR001806; Small_GTPase.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR47980; LD44762P; 1.
DR PANTHER; PTHR47980:SF19; RAS-RELATED PROTEIN RAB-3; 1.
DR Pfam; PF00071; Ras; 1.
DR PRINTS; PR00449; RASTRNSFRMNG.
DR SMART; SM00175; RAB; 1.
DR SMART; SM00176; RAN; 1.
DR SMART; SM00173; RAS; 1.
DR SMART; SM00174; RHO; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51419; RAB; 1.
DR PROSITE; PS51421; RAS; 1.
DR PROSITE; PS51420; RHO; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|RuleBase:RU367096};
KW GTP-binding {ECO:0000256|RuleBase:RU367096};
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288, ECO:0000256|RuleBase:RU367096};
KW Membrane {ECO:0000256|RuleBase:RU367096};
KW Methylation {ECO:0000256|ARBA:ARBA00022481, ECO:0000256|RuleBase:RU367096};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU367096};
KW Prenylation {ECO:0000256|ARBA:ARBA00023289, ECO:0000256|RuleBase:RU367096};
KW Protein transport {ECO:0000256|RuleBase:RU367096};
KW Transport {ECO:0000256|RuleBase:RU367096}.
SQ SEQUENCE 219 AA; 24809 MW; ED8B209379C1DF2A CRC64;
MASANDSKWQ KDAADQNFDY MFKLLIIGNS SVGKTSFLFR YADDSFTSAF VSTVGIDFKV
KTVFRQDKRV KLQIWDTAGQ ERYRTITTAY YRGAMGFILM YDVTNEESFN AVMDWCTQIK
TYSWDNAQVV LVGNKCDLED ERVVSTERGK QLADQIGLEF FETSAKENIN VKAVFERLVD
IICDKMSESL DQDPSLVNSQ TKGTRLTENT APEGGSCQC
//
