ID K1RPV4_CRAGI Unreviewed; 597 AA.
AC K1RPV4;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Potassium voltage-gated channel subfamily KQT member 1 {ECO:0000313|EMBL:EKC36421.1};
GN ORFNames=CGI_10010578 {ECO:0000313|EMBL:EKC36421.1};
OS Crassostrea gigas (Pacific oyster) (Crassostrea angulata).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Bivalvia;
OC Autobranchia; Pteriomorphia; Ostreida; Ostreoidea; Ostreidae; Crassostrea.
OX NCBI_TaxID=29159 {ECO:0000313|EMBL:EKC36421.1};
RN [1] {ECO:0000313|EMBL:EKC36421.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05x7-T-G4-1.051#20 {ECO:0000313|EMBL:EKC36421.1};
RX PubMed=22992520; DOI=10.1038/nature11413;
RA Zhang G., Fang X., Guo X., Li L., Luo R., Xu F., Yang P., Zhang L.,
RA Wang X., Qi H., Xiong Z., Que H., Xie Y., Holland P.W., Paps J., Zhu Y.,
RA Wu F., Chen Y., Wang J., Peng C., Meng J., Yang L., Liu J., Wen B.,
RA Zhang N., Huang Z., Zhu Q., Feng Y., Mount A., Hedgecock D., Xu Z., Liu Y.,
RA Domazet-Loso T., Du Y., Sun X., Zhang S., Liu B., Cheng P., Jiang X.,
RA Li J., Fan D., Wang W., Fu W., Wang T., Wang B., Zhang J., Peng Z., Li Y.,
RA Li N., Wang J., Chen M., He Y., Tan F., Song X., Zheng Q., Huang R.,
RA Yang H., Du X., Chen L., Yang M., Gaffney P.M., Wang S., Luo L., She Z.,
RA Ming Y., Huang W., Zhang S., Huang B., Zhang Y., Qu T., Ni P., Miao G.,
RA Wang J., Wang Q., Steinberg C.E., Wang H., Li N., Qian L., Zhang G., Li Y.,
RA Yang H., Liu X., Wang J., Yin Y., Wang J.;
RT "The oyster genome reveals stress adaptation and complexity of shell
RT formation.";
RL Nature 490:49-54(2012).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; JH816987; EKC36421.1; -; Genomic_DNA.
DR RefSeq; XP_011436471.1; XM_011438169.2.
DR RefSeq; XP_019925450.1; XM_020069891.1.
DR AlphaFoldDB; K1RPV4; -.
DR GeneID; 105334644; -.
DR KEGG; crg:105334644; -.
DR HOGENOM; CLU_011722_8_3_1; -.
DR InParanoid; K1RPV4; -.
DR OMA; ETKETHH; -.
DR OrthoDB; 2911641at2759; -.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 6.10.140.1910; -; 2.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 1.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR003937; K_chnl_volt-dep_KCNQ.
DR InterPro; IPR013821; K_chnl_volt-dep_KCNQ_C.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR47735:SF10; POTASSIUM VOLTAGE-GATED CHANNEL KQT-LIKE SUBFAMILY MEMBER 1; 1.
DR PANTHER; PTHR47735; POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 4; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR Pfam; PF03520; KCNQ_channel; 1.
DR PRINTS; PR00169; KCHANNEL.
DR PRINTS; PR01459; KCNQCHANNEL.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Calmodulin-binding {ECO:0000256|ARBA:ARBA00022860};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 104..334
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT DOMAIN 447..587
FT /note="Potassium channel voltage dependent KCNQ C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03520"
SQ SEQUENCE 597 AA; 68741 MW; C55D9D96B33BAD8F CRC64;
MEAGDETQRA LLNHSTTAPS RLNEEPPTNN NHLSRSPSKR YDAPPGNRTE GSGSAWMEFK
PVINQMDKIL ENKYRVRNKT QMTLTVQGKV YNFLERPTGW KCFIYHFTVF MMVLICLIFS
VLSTIDQYTE FANETLFYME IVLVVFFGLE YVVRLWAAGC RSKYMGLAGR VRFARKPISV
IDFLVVTASI VVLSVGSNGQ VFATSAIRGV RFLQILRMLH VDRQGGTWRL LGSVVYIHRQ
ELITTLYIGF LGLIFSSYFV YLAEKENGST DFTSYADALW WGVITVTTIG YGDTVPQTWM
GRIVASCFSV FAISFFALPA GILGSGFALK VQQKQRQKHF NRQIPTAASL IQCLWRCHAA
EPPFKSSATW KVHIEEKRHF DKHHPGFSKL MNHSMNKLNS KQNSNSMSRI TQKSSLLKKR
RGFSRSASIS DRQGSCQSIP ECPEKTSPDQ ISDENNSQSM EMAEFSIDCQ EEESVSKPQE
LTEQHKIMIR VIRRIKFFVA RRRFQLARKP YDVRDVIEQY SQGHLNMMVR IKELQRRLDT
TLGKPLHVLT RDKERTTVFS KLASMENQMR DLDRKMDQIL VLLHTQHQET RNQYQRP
//
