ID K1VEP4_TRIAC Unreviewed; 702 AA.
AC K1VEP4;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=glycerol kinase {ECO:0000256|ARBA:ARBA00012099};
DE EC=2.7.1.30 {ECO:0000256|ARBA:ARBA00012099};
DE AltName: Full=ATP:glycerol 3-phosphotransferase {ECO:0000256|ARBA:ARBA00043149};
GN ORFNames=A1Q2_08185 {ECO:0000313|EMBL:EKC97521.1};
OS Trichosporon asahii var. asahii (strain CBS 8904) (Yeast).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Trichosporonales; Trichosporonaceae; Trichosporon.
OX NCBI_TaxID=1220162 {ECO:0000313|EMBL:EKC97521.1, ECO:0000313|Proteomes:UP000006757};
RN [1] {ECO:0000313|EMBL:EKC97521.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 8904 {ECO:0000313|EMBL:EKC97521.1};
RX PubMed=23193141; DOI=10.1128/EC.00264-12;
RA Yang R.Y., Li H.T., Zhu H., Zhou G.P., Wang M., Wang L.;
RT "Genome sequence of the Trichosporon asahii environmental strain CBS
RT 8904.";
RL Eukaryot. Cell 11:1586-1587(2012).
RN [2] {ECO:0000313|EMBL:EKC97521.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CBS 8904 {ECO:0000313|EMBL:EKC97521.1};
RA Yang R.-Y., Li H.-T., Zhu H., Zhou G.-P., Wang M., Wang L.;
RL Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Polyol metabolism; glycerol degradation via glycerol kinase
CC pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.
CC {ECO:0000256|ARBA:ARBA00005190}.
CC -!- SIMILARITY: Belongs to the FGGY kinase family.
CC {ECO:0000256|ARBA:ARBA00009156, ECO:0000256|RuleBase:RU003733}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKC97521.1}.
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DR EMBL; AMBO01000409; EKC97521.1; -; Genomic_DNA.
DR AlphaFoldDB; K1VEP4; -.
DR STRING; 1220162.K1VEP4; -.
DR eggNOG; KOG2517; Eukaryota.
DR HOGENOM; CLU_009281_2_1_1; -.
DR InParanoid; K1VEP4; -.
DR OMA; HKTDATN; -.
DR OrthoDB; 2734344at2759; -.
DR UniPathway; UPA00618; UER00672.
DR Proteomes; UP000006757; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004370; F:glycerol kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0019563; P:glycerol catabolic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0006072; P:glycerol-3-phosphate metabolic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.30.420.40; -; 2.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR018483; Carb_kinase_FGGY_CS.
DR InterPro; IPR018485; FGGY_C.
DR InterPro; IPR018484; FGGY_N.
DR InterPro; IPR005999; Glycerol_kin.
DR NCBIfam; TIGR01311; glycerol_kin; 1.
DR PANTHER; PTHR10196:SF69; GLYCEROL KINASE; 1.
DR PANTHER; PTHR10196; SUGAR KINASE; 1.
DR Pfam; PF02782; FGGY_C; 1.
DR Pfam; PF00370; FGGY_N; 2.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR PROSITE; PS00933; FGGY_KINASES_1; 1.
DR PROSITE; PS00445; FGGY_KINASES_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Glycerol metabolism {ECO:0000256|ARBA:ARBA00022798};
KW Kinase {ECO:0000256|RuleBase:RU003733, ECO:0000313|EMBL:EKC97521.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000006757};
KW Transferase {ECO:0000256|RuleBase:RU003733}.
FT DOMAIN 133..253
FT /note="Carbohydrate kinase FGGY N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00370"
FT DOMAIN 272..406
FT /note="Carbohydrate kinase FGGY N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00370"
FT DOMAIN 416..584
FT /note="Carbohydrate kinase FGGY C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02782"
FT REGION 1..76
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 671..702
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 35..52
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 60..76
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 702 AA; 75669 MW; 2060B979CE27D7B0 CRC64;
MADHYDSAIQ DSPTTSPHPS RRPSMVAPRP SYPASTGGAS LSRRSSQHRS GPIPISRADY
SGPTTPSLLS RAGSPTLPLT NDKILSRKSS FAGDAHGARA ALGGGLGGLG GLSGFSALSQ
LDGQRQLRKG EFIGSLDCGT TSTRFIVFDE NAKIITEHQT EFEQVLPYAG WHEQRPEDLV
DAMRECINRA CYKLEWAGWS ADSIRGIGIT NQRETTVCWS KSTGKPLCDA IVWDDTRTVA
VVREFEEKLE KEGIELEEAN GDGKPKRVTG RQGLVDITGI PLSTYFSAIK LRWMLDHYKE
VAEANLAGDL AFGTVDSWLV YNLTGALDGG LHIIDVTNAS RTLLMSLKTL KWSKPLLKFF
GIDESVLPEI VPSAAVYGKI HESMETPLTG VPIAGIVGDQ QAALVGNKCL QRGEAKNTYG
TGAFVLFNTG DEIVHSKNGL ITTVAYQTGK DAQPVYALEG SIAVAGSAIK WLRDQMTLIE
ESAEMDMLAG SVKDTGGVYF VTAFAGLLAP YWDRSATGTI IGMTSYTTSA HIARATLEAV
CFQSRAVLDV IEKEANIKLE GLKVDGGVTN SDLAMQIQAN STALGSALLA GHALGLFGWD
LNKPETLSEV NTADTFVFKP EISDKQRAKM IRGWDRAVAR ARNWHEGEDE LELEERELQI
EKKEGIVDLT MDLGKATLQS SPPSPKILSD PGPVPKPTAA QA
//
