ID   K1W653_MARBU            Unreviewed;       458 AA.
AC   K1W653;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   27-MAR-2024, entry version 38.
DE   SubName: Full=Negative regulator of DNA transposition protein {ECO:0000313|EMBL:EKD12435.1};
GN   ORFNames=MBM_09469 {ECO:0000313|EMBL:EKD12435.1};
OS   Marssonina brunnea f. sp. multigermtubi (strain MB_m1) (Marssonina leaf
OS   spot fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Helotiales; Drepanopezizaceae; Drepanopeziza.
OX   NCBI_TaxID=1072389 {ECO:0000313|EMBL:EKD12435.1, ECO:0000313|Proteomes:UP000006753};
RN   [1] {ECO:0000313|EMBL:EKD12435.1, ECO:0000313|Proteomes:UP000006753}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MB_m1 {ECO:0000313|EMBL:EKD12435.1,
RC   ECO:0000313|Proteomes:UP000006753};
RX   PubMed=22876864; DOI=10.1186/1471-2164-13-382;
RA   Zhu S., Cao Y.-Z., Jiang C., Tan B.-Y., Wang Z., Feng S., Zhang L.,
RA   Su X.-H., Brejova B., Vinar T., Xu M., Wang M.-X., Zhang S.-G.,
RA   Huang M.-R., Wu R., Zhou Y.;
RT   "Sequencing the genome of Marssonina brunnea reveals fungus-poplar co-
RT   evolution.";
RL   BMC Genomics 13:382-382(2012).
CC   -!- FUNCTION: Histones H3 and H4 chaperone involved in the nucleosome
CC       formation and heterochromatin silencing. Required for the deposition of
CC       H3K56ac-carrying H3-H4 complex onto newly-replicated DNA. Plays a role
CC       in the transcriptional regulation of the cell-cycle dependent histone
CC       genes by creating a repressive structure at the core histone gene
CC       promoter. {ECO:0000256|ARBA:ARBA00037550}.
CC   -!- SUBUNIT: Interacts with histones H3 and H4.
CC       {ECO:0000256|ARBA:ARBA00038654}.
CC   -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC   -!- SIMILARITY: Belongs to the RTT106 family.
CC       {ECO:0000256|ARBA:ARBA00006159}.
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DR   EMBL; JH921458; EKD12435.1; -; Genomic_DNA.
DR   RefSeq; XP_007297358.1; XM_007297296.1.
DR   AlphaFoldDB; K1W653; -.
DR   STRING; 1072389.K1W653; -.
DR   GeneID; 18765404; -.
DR   KEGG; mbe:MBM_09469; -.
DR   eggNOG; ENOG502R9PE; Eukaryota.
DR   HOGENOM; CLU_033828_0_0_1; -.
DR   InParanoid; K1W653; -.
DR   OMA; AMPEAHR; -.
DR   OrthoDB; 1359279at2759; -.
DR   Proteomes; UP000006753; Unassembled WGS sequence.
DR   GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.30.29.120; -; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR013719; RTT106/SPT16-like_middle_dom.
DR   PANTHER; PTHR45849; FACT COMPLEX SUBUNIT SSRP1; 1.
DR   PANTHER; PTHR45849:SF3; HISTONE CHAPERONE RTT106; 1.
DR   Pfam; PF08512; Rttp106-like_middle; 1.
DR   SMART; SM01287; Rtt106; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000006753}.
FT   DOMAIN          263..360
FT                   /note="Histone chaperone RTT106/FACT complex subunit SPT16-
FT                   like middle"
FT                   /evidence="ECO:0000259|SMART:SM01287"
FT   REGION          377..458
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        377..399
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        400..436
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   458 AA;  49465 MW;  88199F514AFCAD83 CRC64;
     MGSSSLDEKS LAKAFEGRVD IQGAIRNASA AGPHYIELFN QISQYVCTVI PGNSPEPANK
     KRRIEDQGLV ARPASSGANG HAAIDGATKA AADASSDEPV LLEVKEISVA VPQRKKYTLC
     FTSKHLYARL PDSTEPVPGM SFAWSNIEYA FCLPVPEKTV KQHNYILFPR NSAITPSRPI
     AGASPNIEPL VFTIPDTAPK AGSISGLEAG AAAAVSDDYK TLFDWALSAR FKAAGKSNFK
     ITQADPKSFA SELKQSHRPH EKAVFVKGFR GSKDGYLFFL PNGILWAFKK PLLFLPNERI
     SAVSYTSVLQ RTFNLAVEVD TSVPGEAENK AEYEFAMLDQ EDFVGIGNFV KRHGLQDKSM
     AEQRKAKRLN INAVKDEDGN IIDSEESNEL EKAATEAEQA AMDEEDEDEE DYDPGSEGES
     EGSGSSSEED DSDDEGGTAA GEHSEGDGDG DGHDESEL
//