ID   K1X914_MARBU            Unreviewed;       699 AA.
AC   K1X914;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   27-MAR-2024, entry version 53.
DE   SubName: Full=RhoGAP domain containing protein {ECO:0000313|EMBL:EKD21522.1};
GN   ORFNames=MBM_00635 {ECO:0000313|EMBL:EKD21522.1};
OS   Marssonina brunnea f. sp. multigermtubi (strain MB_m1) (Marssonina leaf
OS   spot fungus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Helotiales; Drepanopezizaceae; Drepanopeziza.
OX   NCBI_TaxID=1072389 {ECO:0000313|EMBL:EKD21522.1, ECO:0000313|Proteomes:UP000006753};
RN   [1] {ECO:0000313|EMBL:EKD21522.1, ECO:0000313|Proteomes:UP000006753}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MB_m1 {ECO:0000313|EMBL:EKD21522.1,
RC   ECO:0000313|Proteomes:UP000006753};
RX   PubMed=22876864; DOI=10.1186/1471-2164-13-382;
RA   Zhu S., Cao Y.-Z., Jiang C., Tan B.-Y., Wang Z., Feng S., Zhang L.,
RA   Su X.-H., Brejova B., Vinar T., Xu M., Wang M.-X., Zhang S.-G.,
RA   Huang M.-R., Wu R., Zhou Y.;
RT   "Sequencing the genome of Marssonina brunnea reveals fungus-poplar co-
RT   evolution.";
RL   BMC Genomics 13:382-382(2012).
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DR   EMBL; JH921428; EKD21522.1; -; Genomic_DNA.
DR   RefSeq; XP_007288524.1; XM_007288462.1.
DR   AlphaFoldDB; K1X914; -.
DR   STRING; 1072389.K1X914; -.
DR   GeneID; 18756570; -.
DR   KEGG; mbe:MBM_00635; -.
DR   eggNOG; KOG1450; Eukaryota.
DR   HOGENOM; CLU_010730_3_0_1; -.
DR   InParanoid; K1X914; -.
DR   OMA; DSGWQAR; -.
DR   OrthoDB; 5482027at2759; -.
DR   Proteomes; UP000006753; Unassembled WGS sequence.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd07652; F-BAR_Rgd1; 1.
DR   CDD; cd04398; RhoGAP_fRGD1; 1.
DR   Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR   Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR031160; F_BAR.
DR   InterPro; IPR001060; FCH_dom.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   PANTHER; PTHR23176:SF138; RHO GTPASE ACTIVATOR; 1.
DR   PANTHER; PTHR23176; RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN; 1.
DR   Pfam; PF00611; FCH; 1.
DR   Pfam; PF00620; RhoGAP; 1.
DR   SMART; SM00055; FCH; 1.
DR   SMART; SM00324; RhoGAP; 1.
DR   SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   PROSITE; PS51741; F_BAR; 1.
DR   PROSITE; PS50238; RHOGAP; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01077};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006753}.
FT   DOMAIN          70..342
FT                   /note="F-BAR"
FT                   /evidence="ECO:0000259|PROSITE:PS51741"
FT   DOMAIN          506..696
FT                   /note="Rho-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50238"
FT   REGION          1..67
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          367..485
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        11..26
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        38..62
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        372..432
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        445..485
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   699 AA;  76163 MW;  B1A7B949A1FE47A6 CRC64;
     MADENPDRIL SEPPDSSNTQ RDGTGSTGTP PPPPNVTATT TASTGDDVSP VNGDSSTDSA
     PPPAVDPNAK AVHEVVNSEI GISTLLNRLK QSIASAKEFA TFLKKRAALE DEHSNGMKKL
     CRVTAESIRR PDHRHGSFLQ SYEEVMTIHE RMSDNGAQFA ISLHQMHDDL GEIATNMERG
     RKQWKTTGLT AEQRAADAEA AMKKSKAKYD SLAEDYDRAK TGDRQQTKKF GLKGPKSSAQ
     VEEDLYRKLK AADEDYASKV QTAQNLRSEL LAKTRPETVK ALEDLINECD SALTLQMQKF
     ASFNEKLLLS NGLNISPLKG NESISKPRSL REVVHAIDNE KDLSKYISGF ASQVPPRTSE
     IKYEKNPVLN NPAPAQRHSD TTASSRSQQQ GLPPQSMGVT QSSQQTHMSH PFNQHPPTPA
     QGPNSSMQQY GTAPPGGPIR GTSYGSGPMG SSGPPQLSSL PFQNSPPPSQ HQSYHPSAVA
     TQAPYSGPPP TLSIVNLPPL KPVFGLSLEQ LFDRDGSAVP MVVYQCIQAV DLFGLEVEGI
     YRLSGTSSHV SKIKALFDND ASKVDFRDPA NFFHDVNSVA GLLKQFFRDL PDPLLTAEHY
     AGFIEAAKNE DDIVRRDSLH AIINSLPDPN YATLRALTLH LNRVQQNSPV NRMNASNLAI
     VFGPTLMGAS TGPNIQDAGW QVRVIDTILQ NTYQIFDDD
//