ID K1XTX9_9BACT Unreviewed; 251 AA.
AC K1XTX9;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 13-SEP-2023, entry version 32.
DE SubName: Full=DNA-directed RNA polymerase subunit alpha {ECO:0000313|EMBL:EKD23883.1};
DE EC=2.7.7.6 {ECO:0000313|EMBL:EKD23883.1};
GN Name=rpoA {ECO:0000313|EMBL:EKD23883.1};
GN ORFNames=ACD_81C00159G0005 {ECO:0000313|EMBL:EKD23883.1};
OS uncultured bacterium.
OC Bacteria; environmental samples.
OX NCBI_TaxID=77133 {ECO:0000313|EMBL:EKD23883.1};
RN [1] {ECO:0000313|EMBL:EKD23883.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23019650; DOI=10.1126/science.1224041;
RA Wrighton K.C., Thomas B.C., Sharon I., Miller C.S., Castelle C.J.,
RA VerBerkmoes N.C., Wilkins M.J., Hettich R.L., Lipton M.S., Williams K.H.,
RA Long P.E., Banfield J.F.;
RT "Fermentation, hydrogen, and sulfur metabolism in multiple uncultivated
RT bacterial phyla.";
RL Science 337:1661-1665(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKD23883.1}.
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DR EMBL; AMFJ01036398; EKD23883.1; -; Genomic_DNA.
DR AlphaFoldDB; K1XTX9; -.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR CDD; cd06928; RNAP_alpha_NTD; 1.
DR Gene3D; 2.170.120.12; DNA-directed RNA polymerase, insert domain; 1.
DR Gene3D; 3.30.1360.10; RNA polymerase, RBP11-like subunit; 1.
DR InterPro; IPR011262; DNA-dir_RNA_pol_insert.
DR InterPro; IPR011263; DNA-dir_RNA_pol_RpoA/D/Rpb3.
DR InterPro; IPR011773; DNA-dir_RpoA.
DR InterPro; IPR036603; RBP11-like.
DR InterPro; IPR036643; RNApol_insert_sf.
DR NCBIfam; TIGR02027; rpoA; 1.
DR Pfam; PF01000; RNA_pol_A_bac; 1.
DR Pfam; PF01193; RNA_pol_L; 1.
DR SMART; SM00662; RPOLD; 1.
DR SUPFAM; SSF56553; Insert subdomain of RNA polymerase alpha subunit; 1.
DR SUPFAM; SSF55257; RBP11-like subunits of RNA polymerase; 1.
PE 4: Predicted;
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478,
KW ECO:0000313|EMBL:EKD23883.1};
KW Nucleotidyltransferase {ECO:0000313|EMBL:EKD23883.1};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transferase {ECO:0000313|EMBL:EKD23883.1}.
FT DOMAIN 21..229
FT /note="DNA-directed RNA polymerase RpoA/D/Rpb3-type"
FT /evidence="ECO:0000259|SMART:SM00662"
SQ SEQUENCE 251 AA; 27575 MW; 38FFDB322AEB2B9A CRC64;
MEYTRLSESV KINTISETDT EGVFEIEGLY SGYGLTVGNS LRRVLLSSLP GACVTQIKIK
NVKHEFTTID GVMEDIVELA LNMKNVRFAL HTDEPQLLTL DVKGEKEVTA GDIKTNAQVD
VINPEAHIAT ITDKKTELSI EITVEKGLGY VPVEARKVEK LPVGVIAIDA IFTPVTNVNF
VVENMRIGER TDFNRVKLTV ETDGSIKPSV AVHKAANILK DHFAKVAEME VAVEEESSEE
EAPAPKKKAK K
//
