ID   K1YRR0_9BACT            Unreviewed;       117 AA.
AC   K1YRR0;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=NAD(P)H steroid dehydrogenase {ECO:0000313|EMBL:EKD35213.1};
DE   Flags: Fragment;
GN   ORFNames=ACD_75C02000G0003 {ECO:0000313|EMBL:EKD35213.1};
OS   uncultured bacterium.
OC   Bacteria; environmental samples.
OX   NCBI_TaxID=77133 {ECO:0000313|EMBL:EKD35213.1};
RN   [1] {ECO:0000313|EMBL:EKD35213.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23019650; DOI=10.1126/science.1224041;
RA   Wrighton K.C., Thomas B.C., Sharon I., Miller C.S., Castelle C.J.,
RA   VerBerkmoes N.C., Wilkins M.J., Hettich R.L., Lipton M.S., Williams K.H.,
RA   Long P.E., Banfield J.F.;
RT   "Fermentation, hydrogen, and sulfur metabolism in multiple uncultivated
RT   bacterial phyla.";
RL   Science 337:1661-1665(2012).
CC   -!- SIMILARITY: Belongs to the 3-beta-HSD family.
CC       {ECO:0000256|ARBA:ARBA00009219}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EKD35213.1}.
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DR   EMBL; AMFJ01032669; EKD35213.1; -; Genomic_DNA.
DR   AlphaFoldDB; K1YRR0; -.
DR   GO; GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR002225; 3Beta_OHSteriod_DH/Estase.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43245; BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA; 1.
DR   PANTHER; PTHR43245:SF51; SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY 42E, MEMBER 2; 1.
DR   Pfam; PF01073; 3Beta_HSD; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
FT   DOMAIN          15..117
FT                   /note="3-beta hydroxysteroid dehydrogenase/isomerase"
FT                   /evidence="ECO:0000259|Pfam:PF01073"
FT   NON_TER         117
FT                   /evidence="ECO:0000313|EMBL:EKD35213.1"
SQ   SEQUENCE   117 AA;  12546 MW;  A1713C8E49F595FC CRC64;
     MGNEKNLALT IKSALVTGGG GFVGRAVVKN LADLGVETRV IGRHSYPEVA AMGARCLIGS
     IADEKIMDRA TDGVDIVFHI AALAGIWGPW KTYHETNVLG TEQVIRSCRK NRVPMLV
//