ID K1Z509_9BACT Unreviewed; 314 AA.
AC K1Z509;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Radical SAM {ECO:0000313|EMBL:EKD44371.1};
GN ORFNames=ACD_71C00160G0002 {ECO:0000313|EMBL:EKD44371.1};
OS uncultured bacterium (gcode 4).
OC Bacteria; environmental samples.
OX NCBI_TaxID=1234023 {ECO:0000313|EMBL:EKD44371.1};
RN [1] {ECO:0000313|EMBL:EKD44371.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23019650; DOI=10.1126/science.1224041;
RA Wrighton K.C., Thomas B.C., Sharon I., Miller C.S., Castelle C.J.,
RA VerBerkmoes N.C., Wilkins M.J., Hettich R.L., Lipton M.S., Williams K.H.,
RA Long P.E., Banfield J.F.;
RT "Fermentation, hydrogen, and sulfur metabolism in multiple uncultivated
RT bacterial phyla.";
RL Science 337:1661-1665(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKD44371.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AMFJ01028891; EKD44371.1; -; Genomic_DNA.
DR AlphaFoldDB; K1Z509; -.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR007197; rSAM.
DR PANTHER; PTHR11228:SF7; PQQA PEPTIDE CYCLASE; 1.
DR PANTHER; PTHR11228; RADICAL SAM DOMAIN PROTEIN; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SFLD; SFLDG01067; SPASM/twitch_domain_containing; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 11..174
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|Pfam:PF04055"
SQ SEQUENCE 314 AA; 35594 MW; 4E1CD6E9CE5FBF4D CRC64;
MEKVKSVNLM ITNRCNSRCN MCNIWKNQVY EDIDLLSLLK LFSREEFSDV QDLSISGGEP
LLKKDINIFA TSLVRLNHNL KLFFVNSNGL LPKKTFELAK ELVSTARIVN PELKVVFSIS
VEGPKEIHER IRGRSYDVAI ETICLLQTLS SDKFEVLVSM TIQKENANHI IDVRSLAKSL
GGGFTFRFAD FSDNYYQNCQ SVNIALTNKE CINVLNDVKK YFIGDAFFKI LFNYVCSGVN
SVMFDSQNKF VCRAGKIFVF IKSNGNIHPC IYSNQIIGNI ENGISPFTLQ KLKSCPCCTE
CNVYPMLLYG NNKT
//
