ID K1Z8L1_9BACT Unreviewed; 473 AA.
AC K1Z8L1;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=Fis family transcriptional regulator {ECO:0008006|Google:ProtNLM};
GN ORFNames=ACD_62C00215G0004 {ECO:0000313|EMBL:EKD51620.1};
OS uncultured bacterium.
OC Bacteria; environmental samples.
OX NCBI_TaxID=77133 {ECO:0000313|EMBL:EKD51620.1};
RN [1] {ECO:0000313|EMBL:EKD51620.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23019650; DOI=10.1126/science.1224041;
RA Wrighton K.C., Thomas B.C., Sharon I., Miller C.S., Castelle C.J.,
RA VerBerkmoes N.C., Wilkins M.J., Hettich R.L., Lipton M.S., Williams K.H.,
RA Long P.E., Banfield J.F.;
RT "Fermentation, hydrogen, and sulfur metabolism in multiple uncultivated
RT bacterial phyla.";
RL Science 337:1661-1665(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKD51620.1}.
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DR EMBL; AMFJ01026018; EKD51620.1; -; Genomic_DNA.
DR AlphaFoldDB; K1Z8L1; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR CDD; cd00060; FHA; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 2.60.200.20; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR002197; HTH_Fis.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR002078; Sigma_54_int.
DR InterPro; IPR025662; Sigma_54_int_dom_ATP-bd_1.
DR InterPro; IPR025943; Sigma_54_int_dom_ATP-bd_2.
DR InterPro; IPR025944; Sigma_54_int_dom_CS.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR PANTHER; PTHR32071:SF57; SIGMA L-DEPENDENT TRANSCRIPTIONAL REGULATOR YQIR-RELATED; 1.
DR PANTHER; PTHR32071; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF00498; FHA; 1.
DR Pfam; PF02954; HTH_8; 1.
DR Pfam; PF00158; Sigma54_activat; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00240; FHA; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR PROSITE; PS50006; FHA_DOMAIN; 1.
DR PROSITE; PS00675; SIGMA54_INTERACT_1; 1.
DR PROSITE; PS00676; SIGMA54_INTERACT_2; 1.
DR PROSITE; PS00688; SIGMA54_INTERACT_3; 1.
DR PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 52..102
FT /note="FHA"
FT /evidence="ECO:0000259|PROSITE:PS50006"
FT DOMAIN 142..375
FT /note="Sigma-54 factor interaction"
FT /evidence="ECO:0000259|PROSITE:PS50045"
SQ SEQUENCE 473 AA; 53785 MW; A8C39732680D13CC CRC64;
MSEETNKDPE FTTAIIAPDE TRDLISLRKY QLIVISKDGN RRKFELGKKK IIRLGKKADN
DIVVNDKTVS RYHSEIHFTD DNSYLVKDIN STNGTTINGM KVKEAYLSQG DLIEIGETKI
EFQTYDESVQ IEPSTTNIFG DMVGKSRKMR QIFGILERIS QSQATVIIEG ETGTGKELVA
RAIHQNSPRK DKPFIVFDCS SVAPNLIESE LFGHTKGSFT GALRDRMGAF EAANGGTIVL
DEIGELNLDL QPKLLRTLEQ REIKRVGSTN SISLDVRLVS ATNRNLKEEV KKGNFREDLY
YRLSVVKIQV PSLRERLEDI PLLVEKILSV ARFNKKQDGS FYVKRVEDDA LKMLQRYQWP
GNVRELTNIL ERAVSFSEDG MIKGAHLQYV FSEVESGEEA TVRLQGIAMD MPFKEAKQAV
VEEFEKEYLQ DLLQRNNGNV SKAAREAKID RKHLRNLLIK YQIIRSDADI LED
//
