ID K2BHN0_9BACT Unreviewed; 444 AA.
AC K2BHN0;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE RecName: Full=Metalloprotease PmbA {ECO:0008006|Google:ProtNLM};
GN ORFNames=ACD_45C00295G0001 {ECO:0000313|EMBL:EKD73512.1};
OS uncultured bacterium.
OC Bacteria; environmental samples.
OX NCBI_TaxID=77133 {ECO:0000313|EMBL:EKD73512.1};
RN [1] {ECO:0000313|EMBL:EKD73512.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23019650; DOI=10.1126/science.1224041;
RA Wrighton K.C., Thomas B.C., Sharon I., Miller C.S., Castelle C.J.,
RA VerBerkmoes N.C., Wilkins M.J., Hettich R.L., Lipton M.S., Williams K.H.,
RA Long P.E., Banfield J.F.;
RT "Fermentation, hydrogen, and sulfur metabolism in multiple uncultivated
RT bacterial phyla.";
RL Science 337:1661-1665(2012).
CC -!- SIMILARITY: Belongs to the peptidase U62 family.
CC {ECO:0000256|ARBA:ARBA00005836}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKD73512.1}.
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DR EMBL; AMFJ01018963; EKD73512.1; -; Genomic_DNA.
DR AlphaFoldDB; K2BHN0; -.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.30.2290.10; PmbA/TldD superfamily; 1.
DR InterPro; IPR045569; Metalloprtase-TldD/E_C.
DR InterPro; IPR045570; Metalloprtase-TldD/E_cen_dom.
DR InterPro; IPR002510; Metalloprtase-TldD/E_N.
DR InterPro; IPR047657; PmbA.
DR InterPro; IPR035068; TldD/PmbA_N.
DR InterPro; IPR036059; TldD/PmbA_sf.
DR PANTHER; PTHR43421; METALLOPROTEASE PMBA; 1.
DR PANTHER; PTHR43421:SF1; METALLOPROTEASE PMBA; 1.
DR Pfam; PF01523; PmbA_TldD_1st; 1.
DR Pfam; PF19290; PmbA_TldD_2nd; 1.
DR Pfam; PF19289; PmbA_TldD_3rd; 1.
DR SUPFAM; SSF111283; Putative modulator of DNA gyrase, PmbA/TldD; 1.
PE 3: Inferred from homology;
FT DOMAIN 30..94
FT /note="Metalloprotease TldD/E N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01523"
FT DOMAIN 122..228
FT /note="Metalloprotease TldD/E central"
FT /evidence="ECO:0000259|Pfam:PF19290"
FT DOMAIN 236..443
FT /note="Metalloprotease TldD/E C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19289"
SQ SEQUENCE 444 AA; 48284 MW; CCF6EA71BCDD8402 CRC64;
MLDVWNNPEH LKSIAVDILR EASKQGASAA EVDIGVNKGF SVTARMGDVE SVEYNQDKVV
DIAVYFGQRT GASSLSDLRP EAIKSAVEAA CHIARFTDKD SCAGLADKDL LAFHYPDLDL
YSPWGITVEE AIDMALTCEG MALAKDKRIT NSEGVQVSTT EGWHIYGNSH DFIGSYGATR
HDISCALIAK QGEDMQRDYN YTVSCDSRLL ESLEFIAHTT VEKTISRLAA KQLTTRSVPV
IFAAEQARSL LGHFVSAISG GNLYRKASFL LDQLGQRIFP EHIQIDEQPH LLKSLGSAPF
DENGVVTRPN VFIDRGILHS YSLGVYSARK LGMQTTGNAG GVHNLLVSTG KKDLSALLKT
MDTGLLITDL MGQGINLVTG DYSRGATGFW VEQGKIQYPV EEITIAGNLR DMYAHLVEVG
CDVDKRGNIQ TGSILLESMT VAGN
//
