ID K2BVQ6_9BACT Unreviewed; 131 AA.
AC K2BVQ6;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=tRNA-specific 2-thiouridylase MnmA {ECO:0000313|EMBL:EKD72933.1};
DE EC=2.1.1.61 {ECO:0000313|EMBL:EKD72933.1};
DE EC=2.8.1.- {ECO:0000313|EMBL:EKD72933.1};
GN Name=mnmA {ECO:0000313|EMBL:EKD72933.1};
GN ORFNames=ACD_45C00511G0001 {ECO:0000313|EMBL:EKD72933.1};
OS uncultured bacterium.
OC Bacteria; environmental samples.
OX NCBI_TaxID=77133 {ECO:0000313|EMBL:EKD72933.1};
RN [1] {ECO:0000313|EMBL:EKD72933.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23019650; DOI=10.1126/science.1224041;
RA Wrighton K.C., Thomas B.C., Sharon I., Miller C.S., Castelle C.J.,
RA VerBerkmoes N.C., Wilkins M.J., Hettich R.L., Lipton M.S., Williams K.H.,
RA Long P.E., Banfield J.F.;
RT "Fermentation, hydrogen, and sulfur metabolism in multiple uncultivated
RT bacterial phyla.";
RL Science 337:1661-1665(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKD72933.1}.
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DR EMBL; AMFJ01019179; EKD72933.1; -; Genomic_DNA.
DR AlphaFoldDB; K2BVQ6; -.
DR GO; GO:0016783; F:sulfurtransferase activity; IEA:InterPro.
DR GO; GO:0004808; F:tRNA (5-methylaminomethyl-2-thiouridylate)(34)-methyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 2.30.30.280; Adenine nucleotide alpha hydrolases-like domains; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR InterPro; IPR046885; MnmA-like_C.
DR InterPro; IPR046884; MnmA-like_central.
DR InterPro; IPR023382; MnmA-like_central_sf.
DR PANTHER; PTHR11933:SF5; MITOCHONDRIAL TRNA-SPECIFIC 2-THIOURIDYLASE 1; 1.
DR PANTHER; PTHR11933; TRNA 5-METHYLAMINOMETHYL-2-THIOURIDYLATE -METHYLTRANSFERASE; 1.
DR Pfam; PF20258; tRNA_Me_trans_C; 1.
DR Pfam; PF20259; tRNA_Me_trans_M; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Methyltransferase {ECO:0000313|EMBL:EKD72933.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transferase {ECO:0000313|EMBL:EKD72933.1}.
FT DOMAIN 1..40
FT /note="tRNA-specific 2-thiouridylase MnmA-like central"
FT /evidence="ECO:0000259|Pfam:PF20259"
FT DOMAIN 50..124
FT /note="tRNA-specific 2-thiouridylase MnmA-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF20258"
SQ SEQUENCE 131 AA; 14749 MW; 727AD536ABCE8141 CRC64;
MYYTIGQRKA LMIGGQKGMP EAPWYVAKKD IQRNVLIVAQ GHDHPSLFTK SLITTTVHWI
NTPPALPLKA MAKTRYRQAD QVCLIESTDN ERCQVTFQIP QRAITPGQSV VFYQDDQCLG
GGVIACRDEN R
//
