ID K2KFP8_HELPX Unreviewed; 391 AA.
AC K2KFP8;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=HNH endonuclease family protein {ECO:0000313|EMBL:EKE86828.1};
GN ORFNames=OUG_1093 {ECO:0000313|EMBL:EKE86828.1};
OS Helicobacter pylori R32b.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=1145112 {ECO:0000313|EMBL:EKE86828.1, ECO:0000313|Proteomes:UP000006767};
RN [1] {ECO:0000313|EMBL:EKE86828.1, ECO:0000313|Proteomes:UP000006767}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R32b {ECO:0000313|EMBL:EKE86828.1,
RC ECO:0000313|Proteomes:UP000006767};
RX PubMed=23661595; DOI=10.1111/2049-632X.12045;
RA Blanchard T.G., Czinn S.J., Correa P., Nakazawa T., Keelan M.,
RA Morningstar L., Santana-Cruz I., Maroo A., McCracken C., Shefchek K.,
RA Daugherty S., Song Y., Fraser C.M., Fricke W.F.;
RT "Genome sequences of 65 Helicobacter pylori strains isolated from
RT asymptomatic individuals and patients with gastric cancer, peptic ulcer
RT disease, or gastritis.";
RL Pathog. Dis. 68:39-43(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKE86828.1}.
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DR EMBL; AMOS01000002; EKE86828.1; -; Genomic_DNA.
DR AlphaFoldDB; K2KFP8; -.
DR PATRIC; fig|1145112.3.peg.1077; -.
DR Proteomes; UP000006767; Unassembled WGS sequence.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd00085; HNHc; 1.
DR InterPro; IPR002711; HNH.
DR InterPro; IPR003615; HNH_nuc.
DR Pfam; PF01844; HNH; 1.
PE 4: Predicted;
KW Endonuclease {ECO:0000313|EMBL:EKE86828.1};
KW Hydrolase {ECO:0000313|EMBL:EKE86828.1};
KW Nuclease {ECO:0000313|EMBL:EKE86828.1}.
FT DOMAIN 308..343
FT /note="HNH"
FT /evidence="ECO:0000259|Pfam:PF01844"
SQ SEQUENCE 391 AA; 46225 MW; D885C657F0E094AD CRC64;
MLLSRFQIKN GCIYGVCSYK ASKSVHGYEE SKAQVLNALN TLSVHPIWRF NQESVTKIRG
TFVFILENDL HLDENAFYKK LLNSLIDNDF FNRSNSMNPN QKRFLSGFFE SRGSIDTQRN
FLTSDYFFHS PLEFNKFHYL IDHFNIPSEA LNFNFRELQP EYAQGINQRN AQFRIYLNWY
LYHIGLFNPY KARIAEHVFK TTLVGDGIYY KLSYPPKAEY RGNSFTERAH FYLKNVYQQD
LDKKSIEKLR EQLGWIQKSE EFKRDSKIIN FYRISTPNVC SACCGNYDIK ERSFISLPLY
KITQDPNSYY TEIHHVISLG KDQELDVLAN LAKLCPTCHR ALKKGSSEEE FQKRLIRNIL
NRNKDNLEFA QLRFETDDFP TLIDRIYESL K
//
