ID K2KHF5_9GAMM Unreviewed; 388 AA.
AC K2KHF5;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=3-oxoacyl-(Acyl carrier protein) synthase I {ECO:0000313|EMBL:EKE76665.1};
DE EC=2.3.1.41 {ECO:0000313|EMBL:EKE76665.1};
GN ORFNames=B3C1_03690 {ECO:0000313|EMBL:EKE76665.1};
OS Gallaecimonas xiamenensis 3-C-1.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Gallaecimonas.
OX NCBI_TaxID=745411 {ECO:0000313|EMBL:EKE76665.1, ECO:0000313|Proteomes:UP000006755};
RN [1] {ECO:0000313|EMBL:EKE76665.1, ECO:0000313|Proteomes:UP000006755}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=3-C-1 {ECO:0000313|EMBL:EKE76665.1,
RC ECO:0000313|Proteomes:UP000006755};
RX PubMed=23209203; DOI=10.1128/JB.01854-12;
RA Lai Q., Wang L., Wang W., Shao Z.;
RT "Genome Sequence of Gallaecimonas xiamenensis Type Strain 3-C-1.";
RL J. Bacteriol. 194:6937-6937(2012).
CC -!- PATHWAY: Lipid metabolism; fatty acid biosynthesis.
CC {ECO:0000256|ARBA:ARBA00005194}.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP
CC synthases family. {ECO:0000256|ARBA:ARBA00008467,
CC ECO:0000256|RuleBase:RU003694}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKE76665.1}.
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DR EMBL; AMRI01000004; EKE76665.1; -; Genomic_DNA.
DR RefSeq; WP_008482999.1; NZ_AMRI01000004.1.
DR AlphaFoldDB; K2KHF5; -.
DR STRING; 745411.B3C1_03690; -.
DR PATRIC; fig|745411.4.peg.728; -.
DR eggNOG; COG0304; Bacteria.
DR OrthoDB; 9808669at2; -.
DR UniPathway; UPA00094; -.
DR Proteomes; UP000006755; Unassembled WGS sequence.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd00834; KAS_I_II; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR000794; Beta-ketoacyl_synthase.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11712:SF320; BETA-KETOACYL SYNTHASE; 1.
DR PANTHER; PTHR11712; POLYKETIDE SYNTHASE-RELATED; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00606; KS3_1; 1.
DR PROSITE; PS52004; KS3_2; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000313|EMBL:EKE76665.1};
KW Fatty acid biosynthesis {ECO:0000256|ARBA:ARBA00023160};
KW Fatty acid metabolism {ECO:0000256|ARBA:ARBA00022832};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00023160};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023160};
KW Reference proteome {ECO:0000313|Proteomes:UP000006755};
KW Transferase {ECO:0000256|RuleBase:RU003694, ECO:0000313|EMBL:EKE76665.1}.
FT DOMAIN 1..386
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
SQ SEQUENCE 388 AA; 39921 MW; D984C1703F8BE571 CRC64;
MTDLYLSAPG IVCPLGAALA PVAEALFAGH SGLVSQDGLL AGRSTWVGAI TAALPAVPSR
LERLDCRNNR ILMLALDQIA PAIDAAKARH GAARVGVVLG SSTAGIDKGE LALKSWQQEG
QLPADFHYEV QTLGSVARFA AQYLGLEGPC YSLSTACSSS GKAFASAQRL IAAGLADAVV
VGGVDSLCRL TLNGFAALES IAPGPCAPFT EGRQGISIGE GAAVFLLSKA PGAVRLAGVG
ESSDGYHISA PDPAGGGARR AMDQALAQAG IEAAQIDYVN LHGTGTPKND EMEGHLMAGY
FPHRPWVSTS KAQVGHALGA AGALEAAFCY LALTQDRLPP QLWRGEPDSQ LPALRFTAPN
QQAPVRYAMS NSYAFGGSNV SVILAHEP
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