ID K2KYV0_HELPX Unreviewed; 255 AA.
AC K2KYV0;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE RecName: Full=Flagellar biosynthetic protein FliR {ECO:0000256|ARBA:ARBA00021717, ECO:0000256|RuleBase:RU362071};
GN Name=fliR {ECO:0000313|EMBL:EKE93033.1};
GN ORFNames=OUM_0257 {ECO:0000313|EMBL:EKE93033.1};
OS Helicobacter pylori R038b.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=1145115 {ECO:0000313|EMBL:EKE93033.1, ECO:0000313|Proteomes:UP000006766};
RN [1] {ECO:0000313|EMBL:EKE93033.1, ECO:0000313|Proteomes:UP000006766}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=R038b {ECO:0000313|EMBL:EKE93033.1,
RC ECO:0000313|Proteomes:UP000006766};
RX PubMed=23661595; DOI=10.1111/2049-632X.12045;
RA Blanchard T.G., Czinn S.J., Correa P., Nakazawa T., Keelan M.,
RA Morningstar L., Santana-Cruz I., Maroo A., McCracken C., Shefchek K.,
RA Daugherty S., Song Y., Fraser C.M., Fricke W.F.;
RT "Genome sequences of 65 Helicobacter pylori strains isolated from
RT asymptomatic individuals and patients with gastric cancer, peptic ulcer
RT disease, or gastritis.";
RL Pathog. Dis. 68:39-43(2013).
CC -!- FUNCTION: Role in flagellar biosynthesis.
CC {ECO:0000256|ARBA:ARBA00002578, ECO:0000256|RuleBase:RU362071}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU362071};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU362071}. Bacterial
CC flagellum basal body {ECO:0000256|RuleBase:RU362071}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FliR/MopE/SpaR family.
CC {ECO:0000256|ARBA:ARBA00009772, ECO:0000256|RuleBase:RU362071}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKE93033.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AMOV01000001; EKE93033.1; -; Genomic_DNA.
DR RefSeq; WP_000883873.1; NZ_AMOV01000001.1.
DR AlphaFoldDB; K2KYV0; -.
DR PATRIC; fig|1145115.3.peg.248; -.
DR Proteomes; UP000006766; Unassembled WGS sequence.
DR GO; GO:0009425; C:bacterial-type flagellum basal body; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:UniProtKB-UniRule.
DR GO; GO:0006605; P:protein targeting; IEA:UniProtKB-UniRule.
DR InterPro; IPR006303; FliR.
DR InterPro; IPR002010; T3SS_IM_R.
DR NCBIfam; TIGR01400; fliR; 1.
DR PANTHER; PTHR30065; FLAGELLAR BIOSYNTHETIC PROTEIN FLIR; 1.
DR PANTHER; PTHR30065:SF8; FLAGELLAR BIOSYNTHETIC PROTEIN FLIR; 1.
DR Pfam; PF01311; Bac_export_1; 1.
DR PRINTS; PR00953; TYPE3IMRPROT.
PE 3: Inferred from homology;
KW Bacterial flagellum {ECO:0000256|RuleBase:RU362071};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU362071};
KW Cell projection {ECO:0000313|EMBL:EKE93033.1};
KW Cilium {ECO:0000313|EMBL:EKE93033.1};
KW Flagellum {ECO:0000313|EMBL:EKE93033.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362071};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362071};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362071}.
FT TRANSMEM 40..58
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362071"
FT TRANSMEM 70..98
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362071"
FT TRANSMEM 128..150
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362071"
FT TRANSMEM 175..201
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362071"
FT TRANSMEM 213..236
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362071"
SQ SEQUENCE 255 AA; 28104 MW; CFCDCC01337AB9AC CRC64;
MLDFLQELST PHVRDFFLLF LRVSGVLSFF PFFENHLVPL SVRGALSLYV SAIFYPTLEF
SNAAYTPESF IIACLCELFL GVYASVFLQI VFASLVFATD SISFSMGLTM ASAYDPISGS
QKPIVGQALL LLAILILLDL SFHHQIILFV DHSLKAVPLG QFVFEPALAK NIVKAFSHLF
VIGFSMAFPI LCLVLLSDII FGMIMKTHPQ FNLLAIGFPV KIAIGFVGII LIASAIMGRF
KEEISLAFSA ISKIF
//
