ID   K2MXW8_TRYCR            Unreviewed;       544 AA.
AC   K2MXW8;
DT   28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT   28-NOV-2012, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=SET domain-containing protein {ECO:0000259|PROSITE:PS50280};
GN   ORFNames=MOQ_005563 {ECO:0000313|EMBL:EKF30624.1};
OS   Trypanosoma cruzi marinkellei.
OC   Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC   Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX   NCBI_TaxID=85056 {ECO:0000313|EMBL:EKF30624.1, ECO:0000313|Proteomes:UP000007350};
RN   [1] {ECO:0000313|EMBL:EKF30624.1, ECO:0000313|Proteomes:UP000007350}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=B7 {ECO:0000313|EMBL:EKF30624.1,
RC   ECO:0000313|Proteomes:UP000007350};
RX   PubMed=23035642; DOI=10.1186/1471-2164-13-531;
RA   Franzen O., Talavera-Lopez C., Ochaya S., Butler C.E., Messenger L.A.,
RA   Lewis M.D., Llewellyn M.S., Marinkelle C.J., Tyler K.M., Miles M.A.,
RA   Andersson B.;
RT   "Comparative genomic analysis of human infective Trypanosoma cruzi lineages
RT   with the bat-restricted subspecies T. cruzi marinkellei.";
RL   BMC Genomics 13:531-531(2012).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EKF30624.1}.
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DR   EMBL; AHKC01011913; EKF30624.1; -; Genomic_DNA.
DR   AlphaFoldDB; K2MXW8; -.
DR   EnsemblProtists; EKF30624; EKF30624; MOQ_005563.
DR   OrthoDB; 130527at2759; -.
DR   Proteomes; UP000007350; Unassembled WGS sequence.
DR   CDD; cd10527; SET_LSMT; 1.
DR   Gene3D; 3.90.1410.10; set domain protein methyltransferase, domain 1; 1.
DR   InterPro; IPR001214; SET_dom.
DR   InterPro; IPR046341; SET_dom_sf.
DR   PANTHER; PTHR13271:SF161; SET DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR13271; UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE; 1.
DR   Pfam; PF00856; SET; 1.
DR   SUPFAM; SSF82199; SET domain; 1.
DR   PROSITE; PS50280; SET; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000007350};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           24..544
FT                   /note="SET domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003861638"
FT   DOMAIN          26..383
FT                   /note="SET"
FT                   /evidence="ECO:0000259|PROSITE:PS50280"
FT   REGION          439..458
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   544 AA;  60998 MW;  6878E1B65155F4F7 CRC64;
     MQCTRPALSI AAWSSGLVGF SDAVVQVVQR KKTLGSTEGG GGGGEGNVTP VRCILATRAI
     CRGEKLCIVP ESHILHGENA ARLLQRAAAE RLLSNYATTQ RCLANVTGDT SIISTRDALL
     ILLAVHVLRQ GRMTHPLTPW SACLPPRVPP MGVFLQQSHQ HHAGMASFEP LQRRLRMGEQ
     MIALHPGEED TKKASTELIL QAAEQYGIEC VGKPQTEVTP SQALMTSFYR GTRHPLTRRQ
     HEAYTAQHRH ILSAETRQLL QLEESLHRIV IKPLLPCLLS ESNECRNNDT GDGALLSEDC
     DSEAKMAIIE QLRWSHFMVR SRAVNLQPQR HYQPHIALVP FLDMLNHSVR DANVAYQYRP
     GVGVVVVASR PIKATEELTI NYGDYRQRGC LFSYAQEHKA GGEEIGAAMR RIESRQMREW
     DDSPNDDNAD DLVEAPFGHG MQQQQQKQQH ASDVDSNEEA RTEATWLWRF GFSRTDDEKA
     YIASRLWSKG LRQRIAQLTD VRRKGRPGEF VIGVPEGLQQ LREQRERLER ERFGGAAVFP
     PQNV
//