ID K2MZ21_TRYCR Unreviewed; 557 AA.
AC K2MZ21;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 22-FEB-2023, entry version 35.
DE SubName: Full=GTP-ase activating protein, putative {ECO:0000313|EMBL:EKF32335.1};
GN ORFNames=MOQ_003817 {ECO:0000313|EMBL:EKF32335.1};
OS Trypanosoma cruzi marinkellei.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=85056 {ECO:0000313|EMBL:EKF32335.1, ECO:0000313|Proteomes:UP000007350};
RN [1] {ECO:0000313|EMBL:EKF32335.1, ECO:0000313|Proteomes:UP000007350}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B7 {ECO:0000313|EMBL:EKF32335.1,
RC ECO:0000313|Proteomes:UP000007350};
RX PubMed=23035642; DOI=10.1186/1471-2164-13-531;
RA Franzen O., Talavera-Lopez C., Ochaya S., Butler C.E., Messenger L.A.,
RA Lewis M.D., Llewellyn M.S., Marinkelle C.J., Tyler K.M., Miles M.A.,
RA Andersson B.;
RT "Comparative genomic analysis of human infective Trypanosoma cruzi lineages
RT with the bat-restricted subspecies T. cruzi marinkellei.";
RL BMC Genomics 13:531-531(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKF32335.1}.
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DR EMBL; AHKC01009891; EKF32335.1; -; Genomic_DNA.
DR AlphaFoldDB; K2MZ21; -.
DR EnsemblProtists; EKF32335; EKF32335; MOQ_003817.
DR OrthoDB; 119920at2759; -.
DR Proteomes; UP000007350; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR GO; GO:0005543; F:phospholipid binding; IEA:InterPro.
DR Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR InterPro; IPR044518; ARF_GAP_AGD11/12/13.
DR InterPro; IPR037278; ARFGAP/RecO.
DR InterPro; IPR001164; ArfGAP_dom.
DR InterPro; IPR038508; ArfGAP_dom_sf.
DR PANTHER; PTHR46220; ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN AGD12; 1.
DR PANTHER; PTHR46220:SF1; ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN AGD12; 1.
DR Pfam; PF01412; ArfGap; 1.
DR PRINTS; PR00405; REVINTRACTNG.
DR SMART; SM00105; ArfGap; 1.
DR SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR PROSITE; PS50115; ARFGAP; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00288};
KW Reference proteome {ECO:0000313|Proteomes:UP000007350};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00288};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00288}.
FT DOMAIN 239..363
FT /note="Arf-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50115"
FT REGION 214..237
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 557 AA; 62899 MW; 5FF0E74C42616A35 CRC64;
MMEATLETLL LSGAASCRFI WRKRPKVMRT IEIHTDGVLY CFDEPKDSMA KNLRERLYLF
GSRVVDCGTH RGRLCFGLEL ADASSVEQLR PSGLFTSLRT SAPVSFLKNE ESLSNRFVAF
FFVGNKLLKW RFIHLLRLAS SALPPFSELL QQEQNLALSA SCGSYENDGN RGMYRILERP
SRIIDVTGDG PLEMHEVEQL EDVLRLYEEN KRLKQEEEDN NDEEESLHES VVTSDDNKME
VPERLMQSPL YAPCIAERPS NQVCADCGEK WPTWAVLGPF GCFVCIHCVG VHRQLRPQCC
REVQLDNWDA AEIEFMAKRG NDVVNDELEY AGFFLGNGDA VYKPVGSSSR REVREEYITL
KYEGAFTRER NPHVLHAMVP PPDRDVQGHV DISPHGALNH DGPPQYIGVA YINVREVEGI
RSNGAVLSLT NGFQEVRSRP GVVPSGPAKN NPCHACTCWE ESFQLGVYSF TAPLFMALYT
SGDELLGAAE WRLPDGAALP GCEPQLVRVP LFWCLPAKGS TWPTFNPFGR GRRRRKRDAE
TWRQPLLYIT VSFAHFG
//
