ID K2N3I3_TRYCR Unreviewed; 336 AA.
AC K2N3I3;
DT 28-NOV-2012, integrated into UniProtKB/TrEMBL.
DT 28-NOV-2012, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Trans-sialidase, putative {ECO:0000313|EMBL:EKF29171.1};
DE Flags: Fragment;
GN ORFNames=MOQ_007059 {ECO:0000313|EMBL:EKF29171.1};
OS Trypanosoma cruzi marinkellei.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Schizotrypanum.
OX NCBI_TaxID=85056 {ECO:0000313|EMBL:EKF29171.1, ECO:0000313|Proteomes:UP000007350};
RN [1] {ECO:0000313|EMBL:EKF29171.1, ECO:0000313|Proteomes:UP000007350}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B7 {ECO:0000313|EMBL:EKF29171.1,
RC ECO:0000313|Proteomes:UP000007350};
RX PubMed=23035642; DOI=10.1186/1471-2164-13-531;
RA Franzen O., Talavera-Lopez C., Ochaya S., Butler C.E., Messenger L.A.,
RA Lewis M.D., Llewellyn M.S., Marinkelle C.J., Tyler K.M., Miles M.A.,
RA Andersson B.;
RT "Comparative genomic analysis of human infective Trypanosoma cruzi lineages
RT with the bat-restricted subspecies T. cruzi marinkellei.";
RL BMC Genomics 13:531-531(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKF29171.1}.
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DR EMBL; AHKC01013923; EKF29171.1; -; Genomic_DNA.
DR AlphaFoldDB; K2N3I3; -.
DR EnsemblProtists; EKF29171; EKF29171; MOQ_007059.
DR OrthoDB; 2900690at2759; -.
DR Proteomes; UP000007350; Unassembled WGS sequence.
DR GO; GO:0004308; F:exo-alpha-sialidase activity; IEA:InterPro.
DR CDD; cd15482; Sialidase_non-viral; 1.
DR Gene3D; 2.120.10.10; -; 1.
DR InterPro; IPR011040; Sialidase.
DR InterPro; IPR026856; Sialidase_fam.
DR InterPro; IPR036278; Sialidase_sf.
DR InterPro; IPR008377; Sialidase_trypan.
DR PANTHER; PTHR10628; SIALIDASE; 1.
DR PANTHER; PTHR10628:SF25; SIALIDASE-1; 1.
DR Pfam; PF13859; BNR_3; 1.
DR PRINTS; PR01803; TCSIALIDASE.
DR SUPFAM; SSF50939; Sialidases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007350};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 107..335
FT /note="Sialidase"
FT /evidence="ECO:0000259|Pfam:PF13859"
FT REGION 1..37
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..21
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 22..37
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 336
FT /evidence="ECO:0000313|EMBL:EKF29171.1"
SQ SEQUENCE 336 AA; 36368 MW; 09AA02D6EA436D1B CRC64;
MHSRVAAVRA PRTHNRRRVT GSSGRRREGR ESEPQRPNMS RRVFTFAVLL LLVVMWMCCG
SGAANAVESR SGDAQQPQLA DIFVPGKTQV VAKDGSASGT MLSFSIPSLT SAGGVMAVFA
QGVVLHFSPD EQKKGVSQAD VVAGYINSAW DWSSLVAEVN MNTWRAYAIL SIKREADLVG
IAFNPTTIAK GNKVFLLVGS GERKYDNNTK NWKLSDTDIQ LVVGEATQFK EGEQSGKINW
SGPVSLLKQI TDGSQSDAKA FYPGGGTGVL MEDGTLVLPV QGENDNEPIP MIIYSTDDGN
SWDVSKGTPP AKCLNIRITE WEKGQILMVL QCENGQ
//
